Preoperative and Postoperative Mitral Valve Prolapse and Regurgitation in Adult Patients with Secundum Atrial Septal Defects

Abstract

Preoperative MR severity was associated with TR severity, dilated left heart chambers, and MV prolapse. MR decreased after ASD closure with and even without MV surgery.

Biatrial ablation versus limited right atrial ablation for atrial fibrillation associated with atrial septal defect in adults

“…It is well known that some adults with aSD have Mr or Tr, the mechanism of which is considered to be related to heart volume overload and annular dilatation, caused by the long-standing left-to-right shunt [27,28]. If Mr or Tr was more than mild, we would perform mitral or tricuspid valvuloplasty and would also use a 'c' prosthetic ring when regurgitation was more than moderate.…”

Congenital Ostium Secundum Atrial Septal Defect with Mitral Valve Prolapse and Mitral Regurgitation – A Case Report and Review of Literature

“…This incidence increases with age which can progress after operation done during adulthood. 1 Most of the patients with MVP are asymptomatic. However, systolic clicks or mid to late systolic murmur during auscultation helps to diagnose MVP.…”

“…An ostium secundum Atrial Septal Defect (ASD) is an abnormally large opening in the atrial septum at the site of the foramen ovale and the ostium secundum.Secundum ASD is not widely associated with Mitral regurgitation (MR) although the association is not unusual.Mitral valve (MV) prolapse which is caused by abnormal geometry of the left ventricle (LV) and MV apparatus secondary to right ventricular (RV) volume overload is the major cause of MRwhich is found in less than 10% of adults with large ASD. [1] Researches have shown disease of mitral valve prolapse, congenital valve deformity, rheumatic valve, and specific pathophysiology complex as main causes of mitral regurgitation in patient with ASD. [2] In this study, we report a case of congenital ostium secundum ASD with MVP attributing to MR, review the clinical relevance of this association, and discuss the related literature.…”

Demonstration of Mitral Valve Prolapse with CT for Planning of Mitral Valve Repair

“…Atrial septal defect with right ventricular volume overload may cause MVP by altering the geometric features of the left ventricle and affecting the mitral valve apparatus (Fig 6e) (25). Fewer than 10% of patients with atrial septal defect have mitral regurgitation, and the severity of mitral regurgitation may decrease after closure of the atrial septal defect regardless of whether the mitral valve was repaired (25).…”