Prenylflavonoids from Flourensia fiebrigii

Uriburu, María L.; Gil, Roberto R.; Sosa, Virginia E.; Fuente, Juana R. de la

doi:10.1016/j.phytochem.2007.01.004

Cited by 15 publications

(16 citation statements)

References 18 publications

(17 reference statements)

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“…Se identifi caron los componentes del aceite esencial de F. oolepis S. F. Blake (Priotti et al 1997;García et al 2007;Díaz Nepal et al 2009) y se comprobó su efecto bactericida (Carrizo Flores et al 2005;Vaca Ruiz et al 2006;Joray et al 2011), insecticida (García et al 2007), antifúngico (Carpinella et al 2010) y protector contra úlceras gástricas (Donadel et al 2005). Además, se estudiaron los compuestos químicos en F. campestris Griseb., F. riparia Griseb., F. fi ebrigii S. F. Blake (Uriburu et al 2004(Uriburu et al , 2005(Uriburu et al , 2007, F. blakeana Dillon (Pacciaroni et al 2009), F. heterolepis S. F. Blake (Bohlmann & Jakupovic 1979) y F. cernua DC. (Rao et al 1970;Estell et al 1996;Tellez et al 1997).…”

Section: Introductionunclassified

Exomorfología y anatomía de órganos vegetativos aéreos en especies de Flourensia DC. (Asteraceae) con importancia fitoquímica

Delbón

Cosa

Bernardello³

2012

Acta Bot. Bras.

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Blake y F. tortuosa Griseb., especies endémicas del centro de Argentina. Se observó que todas son similares en cuanto a la anatomía de hoja y tallo. En cuanto al estudio de la epidermis foliar, se concluye que es posible diferenciar las especies teniendo en cuenta la frecuencia estomática y la presencia de tricomas. Finalmente, las diferencias más notables se encontraron en la exomorfología foliar ya que se observó una gran variación en cuanto a la forma de las hojas y tamaño de las láminas y pecíolos. Con respecto a las estructuras secretoras, se encontraron tricomas y conductos secretores esquizógenos en las hojas y los tallos de todas las especies, las cuales serían responsables de la producción y secreción de las resinas. ABSTRACT(Exomorphology and anatomy of vegetative organs in Flourensia species (Asteraceae) with phytochemical importance). Th e genus Flourensia DC. is American and comprises 32 species. Th ey are resiniferous shrubs used in folk medicine. As they have potential economic value, its chemical compounds have been characterized and some possible uses identifi ed. In this work, the exomorphology and anatomy of vegetative organs of F. hirta S. F. Blake, F. leptopoda S. F. Blake, F. niederleinii S. F. Blake and F. tortuosa Griseb., endemic species from central Argentina, have been studied. All species are similar in leaf and stem anatomy. Regarding the epidermis, it is possible to diff erentiate the species according to the stomatal frequency and the presence of trichomes. Finally, the most remarkable diff erences were found in leaf exomorphology, since there was a large variation in shape and size of blades and petioles. Concerning the secretory structures, trichomes and secretory ducts were found in the leaves and stems of all species, which would be responsible for the production and secretion of the resins.

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Section: Introductionunclassified

Exomorfología y anatomía de órganos vegetativos aéreos en especies de Flourensia DC. (Asteraceae) con importancia fitoquímica

Delbón

Cosa

Bernardello³

2012

Acta Bot. Bras.

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“…The benzofuran tremetone (2,3‐dihydro‐2‐isopropenyl‐5‐benzofuranyl methyl ketone) (), a putative vascular plant marker, was identified in all of the modern ice core samples. It has been identified in extracts from rayless goldenrod [ Zalkow et al , 1979] and an Argentinean plant of the Asteraceae family [ Uriburu et al , 2007], and has also been found in Brazilian propolis, which is a constituent of honeybee hives originating from local vegetation [ Banskota et al , 1998]. This compound was observed in samples from all five sites (Figure 1), but occurred in the greatest abundances in the Sajama samples and was not detected in any blanks ().…”

Section: Resultsmentioning

confidence: 96%

High‐sensitivity measurement of diverse vascular plant‐derived biomarkers in high‐altitude ice cores

Makou

Thompson

Montluçon

et al. 2009

Geophysical Research Letters

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Semi‐volatile organic compounds derived from burned and fresh vascular plant sources and preserved in high‐altitude ice fields were detected and identified through use of recently developed analytical tools. Specifically, stir bar sorptive extraction and thermal desorption coupled with gas chromatography/time‐of‐flight mass spectrometry allowed measurement of multiple biomarkers in small sample volumes (≤30 ml). Among other compounds of interest, several diterpenoids, which suggest inputs from conifers and conifer burning, were identified in post‐industrial era and older Holocene ice from the Sajama site in the Bolivian Andes, but not in a glacial period sample, consistent with aridity changes. Differences in biomarker assemblages between sites support the use of these compounds as regionally constrained recorders of vegetation and climate change. This study represents the first application of these analytical techniques to ice core research and the first indication that records of vegetation fires may be reconstructed from diterpenoids in ice.

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“…A. integer leaves and stem bark were dried and extracted using EtOH. These crude extracts were fractioned and purified using chromatographic techniques to furnish kuwanon R ( 1 ), [17] kuwanon J ( 2 ), [18] deoxyartonin I ( 3 ), [19] artocarmitins A ( 4 ), [20] isogemichalcone B ( 5 ), [21] sanjuanolide ( 6 ), [22] morachalcone A ( 7 ), [23] bavachromanol ( 8 ), [24] 5,7,4 ′ ‐trihydroxy‐6‐[40‐methylbut‐30‐enyl]‐flavone ( 9 ), [25] dinklagin C ( 10 ), [25] apigenin ( 11 ), [26] quercetin ( 12 ), [27] (2 S )‐8‐(3′′‐methylbut‐2′′‐enyl)‐7,3′,4′‐trihydroxyflavanone ( 13 ), [28] (−)‐epiafzelechin ( 14 ), [29] cis‐ 3,4′‐dihydroxy‐5,7‐dimethoxyflavan ( 15 ), [30] 4‐(3′,4′‐dihydroxyphenyl)butan‐2‐one ( 16 ), [31] (+)‐catechin ( 17 ), [32] and indole ( 18 ) [33] . These were identified by comparing their NMR spectra with published data ( Figure 1).…”

Section: Resultsmentioning

confidence: 99%

Identification of Highly Potent α‐Glucosidase Inhibitors from Artocarpus integer and Molecular Docking Studies

Duong

Nguyen

et al. 2021

Chemistry & Biodiversity

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A new natural Diels-Alder adduct (3) was isolated from the leaves and stem bark of Artocarpus integer, along with seventeen known compounds (1, 2, and 4-18). Structural elucidation was conducted using NMR and HR-ESI-MS data, and comparisons were made with previous studies. Deoxyartonin I (3) exhibited the most potent α-glucosidase inhibition (IC 50 7.80 � 0.1 μM), outperforming the acarbose positive control. This was mixed-mode inhibition, as indicated by the intersect in the second quadrant of each respective plot. An in silico molecular docking model and the pharmacokinetic features of 3 suggest that it is a potential inhibitor of enzyme α-glucosidase, and is therefore a lead candidate as a drug against diabetes mellitus.

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Prenylflavonoids from Flourensia fiebrigii

Cited by 15 publications

References 18 publications

Exomorfología y anatomía de órganos vegetativos aéreos en especies de Flourensia DC. (Asteraceae) con importancia fitoquímica

Exomorfología y anatomía de órganos vegetativos aéreos en especies de Flourensia DC. (Asteraceae) con importancia fitoquímica

High‐sensitivity measurement of diverse vascular plant‐derived biomarkers in high‐altitude ice cores

Identification of Highly Potent α‐Glucosidase Inhibitors from Artocarpus integer and Molecular Docking Studies

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