Prenylated flavonoids from Maclura pomifera

Lee, Sang-Jun; Wood, Angela R.; Maier, Camelia; Dixon, Richard A.; Mabry, Tom J.

doi:10.1016/s0031-9422(98)00380-x

Cited by 34 publications

(23 citation statements)

References 10 publications

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“…Purity of the two compounds (osajin and pomiferin) were monitored by TLC and H 1 NMR. The data obtained were identical with those reported in the literature (Monache et al, 1994;Lee et al, 1998).…”

Section: Extraction and Isolation Of Plant Materilsupporting

confidence: 89%

“…Different metabolites have been isolated from the fruits and other parts of Maclura pomifera tree (Monache et al, 1994 andLee et al, 1998). Osajin and pomiferin show antimicrobial activity and fruit extracts are also used in animal immunological studies (Ismail et al, 2001 So the objective of this study was to investigate the antioxidant activity of the total acetonic extract of Maclura pomifera and its two major constituents pomiferin and osajin.…”

Section: Introductionmentioning

confidence: 99%

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Effect of <i>Maclura pomifera</i> total acetonic extract, pomiferin and osajin on the autooxidation of purified sunflower triacylglycerols

Hamed¹,

Hussein²

2005

Grasas y Aceites

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RESUMENEfecto sobre la oxidación de triglicéridos purificados del aceite de girasol, del extracto de acetona del fruto de Maclura pomifera, de la pomiferina y de la osajina.Se han aislado la pomiferina y la osajina del extracto de hexano del fruto de M. pomifera. Se han estudiado los efectos sobre la oxidación de triglicéridos purificados del aceite de girasol, del extracto de acetona, de la pomiferina y de la osajina. La pomiferina mostró una actividad antioxidante elevada en cambio, el extracto de acetona mostró una actividad moderada y la osajina baja. PALABRAS-CLAVE: Aceite de girasol -Antioxidante -Autoxidación -Maclura pomifera -Osajina -Pomiferina -Triglicérido. SUMMARYEffect of Maclura pomifera total acetonic extract, pomiferin and osajin on the autooxidation of purified sunflower triacylglycerols.Pomiferin and osajin have been isolated from the acetonic extract of M. pomifera fruits. Effects of total acetonic extract, pomiferin and osajin on the autooxidation of purified sunflower triacylglycerol were studied. Pomiferin showed a high antioxidant activity whereas total acetonic extract showed moderate and osajin revealed a low activity.

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Section: Extraction and Isolation Of Plant Materilsupporting

confidence: 89%

Section: Introductionmentioning

confidence: 99%

Effect of <i>Maclura pomifera</i> total acetonic extract, pomiferin and osajin on the autooxidation of purified sunflower triacylglycerols

Hamed¹,

Hussein²

2005

Grasas y Aceites

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“…Nevertheless, preliminary data from the "osage orange" (Maclura pomifera, Moraceae) indicate that male and female branches of this dioecious species contain very different levels of a compound(s) able to activate human ER in yeast (124). M. pomifera fruit contain up to 6% dry mass of the di-prenylated isoflavone derivatives pomiferin and osajin, with smaller amounts of prenylated isoflavones and flavones with known in vitro ER activation activity in other parts of the plant (111). Whether the ERactivating compound(s) of M. pomifera truly play a role in sex determination in this species has not been determined.…”

Section: Phytoestrogens and Sex Determination In Plantsmentioning

confidence: 99%

Phytoestrogens

Dixon

2004

Annu. Rev. Plant Biol.

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442

319

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▪ Abstract Collectively, plants contain several different families of natural products among which are compounds with weak estrogenic or antiestrogenic activity toward mammals. These compounds, termed phytoestrogens, include certain isoflavonoids, flavonoids, stilbenes, and lignans. The best-studied dietary phytoestrogens are the soy isoflavones and the flaxseed lignans. Their perceived health beneficial properties extend beyond hormone-dependent breast and prostate cancers and osteoporosis to include cognitive function, cardiovascular disease, immunity and inflammation, and reproduction and fertility. In the future, metabolic engineering of plants could generate novel and exquisitely controlled dietary sources with which to better assess the potential health beneficial effects of phytoestrogens.

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“…1) were identified as erythrinin B, 21) abyssinin II, 22) and parvisoflavone B, 23) respectively, by comparing their physical ([a] D ) and spectroscopic (UV, MS, NMR) data with those reported in the literature. All the isolates were assayed for their inhibitory activity against PTP1B in vitro using a described method, [6][7][8][9] and the results are presented in Table 2.…”

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confidence: 99%

Prenylated Flavonoids with PTP1B Inhibitory Activity from the Root Bark of Erythrina mildbraedii

Jang

Thương

et al. 2008

CHEMICAL & PHARMACEUTICAL BULLETIN

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Phytochemical study on an EtOAc-soluble extract of the root bark of Erythrina mildbraedii resulted in the isolation of six prenylated flavonoids 1-6. Based on physicochemical and spectroscopic analyses, their structures were determined to be new natural products licoflavanone-4-O-methyl ether (1), 2,7-dihydroxy-4-methoxy-5-(3-methylbut-2-enyl)isoflavone (2), and (3R)-2,7-dihydroxy-3-(3-methylbut-2-enyl)

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Prenylated flavonoids from Maclura pomifera

Cited by 34 publications

References 10 publications

Effect of <i>Maclura pomifera</i> total acetonic extract, pomiferin and osajin on the autooxidation of purified sunflower triacylglycerols

Effect of <i>Maclura pomifera</i> total acetonic extract, pomiferin and osajin on the autooxidation of purified sunflower triacylglycerols

Phytoestrogens

Prenylated Flavonoids with PTP1B Inhibitory Activity from the Root Bark of Erythrina mildbraedii

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