Prenatal ultrasound detection of bilateral focal polymicrogyria

Abstract

Polymicrogyria can be considered in the differential diagnosis of hyperechogenic brain lesions on fetal ultrasound. We also confirm the risk of brain damage in monochorionic twins pregnancies and the likely hypoxic-ischemic etiology of polymicrogyria.

Accurate neurosonographic prediction of brain injury in the surviving fetus after the death of a monochorionic cotwin

“…The ultrasound appearance of the brain lesions was variable, and included both hemorrhagic and hypoxic‐ischemic lesions. Similar to another recent case, hyperechogenicity of the cerebral cortex was the harbinger of the subsequent development of a cortical abnormality, polymicrogyria12. There was frequently a latency between the time of fetal death and the development of abnormal sonographic findings in the survivor.…”

Fetal and postnatal brain MRI in premature infants with twin–twin transfusion syndrome

“…Polymicrogyria is thought to occur during or after the neuronal migration period. 25 It has been described before in case reports of infants with TTTS, [26][27][28] and in the infant in our study it may have been due to a vascular insult that occurred after the fetal MRI, performed at about 20 weeks in this patient. Multiple types of brain injury have been described in infants with TTTS.…”

Abnormal Sylvian fissure on prenatal cerebral imaging: significance and correlation with neuropathological and postnatal data

“…Unexpectedly, only one third ( n = 5) of the cases in our series of 15 fetuses with abnormal operculization had underlying cortical dysplasia (Cases 1–5). Three of these fetuses had diffuse polymicrogyria, a cortical malformation rarely reported in the prenatal imaging literature14–17. The other two had a diffuse cortical malformation with a lissencephalic appearance, related to true lissencephaly Type 1 in one case; the other was an exceptional case of cortical hypoplasia with hyperplasia of the germinative zones.…”