Prenatal Substance Use Disorders and Dental Caries in Children

Auger, Nathalie; Low, Nancy; Lee, Ga Eun; Ayoub, Aimina; Nicolau, Bélinda

doi:10.1177/0022034520906820

Cited by 12 publications

(9 citation statements)

References 34 publications

(53 reference statements)

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“…The use of the maternal substance was associated with 1.96 times the risk of dental caries in childhood compared to the use of no substance. Associations were high for alcohol but were also present for cocaine, cannabis, opioids, and other substances [15].…”

Section: Resultsmentioning

confidence: 96%

The importance of prenatal dental care: a concise systematic review

Lima

Martins

Moura

et al. 2021

MedNEXT

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Introduction: Prenatal dental care is extremely important, as it requires a series of specific care for pregnant patients. There is a need for specific care with the health of the mouth and informing the patient of essential care for her and her baby's health. Also, the microorganisms that cause these diseases can migrate to the uterus and cause premature births. Several studies show that dental care was considered safe for the mother and fetus throughout the entire period of pregnancy. Objective: To carry out a brief systematic review of the literature to elucidate the main considerations for success during the treatment of oral health in pregnant women. Methods: The research was carried out from May 2021 to June 2021 and developed based on Scopus, PubMed, Science Direct, Scielo, and Google Scholar, following the Systematic Review-PRISMA rules. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results: A total of 244 articles were found. A total of 76 articles were evaluated in full and 19 were included and evaluated in the present study. A total of 3 Studies with a High Risk of Bias and 1 Study with Uncertain Risk. Studies have suggested a protective effect of prenatal oral health care against the onset of caries in infancy and up to before 4 years of age. The transport of S. mutans in children was also significantly reduced in the intervention group. Children exposed to the use of maternal substances had a higher incidence of hospitalization for dental caries than unexposed children. Thus, inadequate prenatal education in oral health can negatively impact the quality of oral hygiene in children. It is imperative to develop strategies to improve oral health and develop a health system strengthening by interprofessional collaboration in the prenatal phase of pregnant women. Furthermore, an inverse relationship was observed between 25(OH)D levels and the number of decayed primary teeth. Conclusion: Taking care of oral health is part of the daily rhythm of personal hygiene. The monitoring of a dental surgeon during pregnancy is considered to prevent and treat the pregnant woman's oral diseases and clarify the doubts of future mothers since the baby's oral health begins to establish itself during the gestational period.

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Section: Resultsmentioning

confidence: 96%

The importance of prenatal dental care: a concise systematic review

Lima

Martins

Moura

et al. 2021

MedNEXT

View full text Add to dashboard Cite

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“…A national consensus statement on oral health care during pregnancy recommends that, in addition to obtaining a patient's medical and dental history, oral health professionals should review tobacco, alcohol, and recreational drug use as well as provide patient-centered resources and actions to mitigate these substance-use behaviors [Workgroup, 2012]. This is important, given that, not only is smoking during pregnancy harmful, prenatal substance-use disorders were reported in a recent study to be positively associated with increased offspring caries in 12-year-old children [Auger et al, 2020].…”

Section: Discussionmentioning

confidence: 99%

Does the Trimester of Smoking Matter in the Association between Prenatal Smoking and the Risk of Early Childhood Caries?

Akinkugbe

2021

Caries Res

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Introduction: Development of the primary tooth bud commences at the end of the 5th week of gestation, with mineralization starting at about the 13th week and continuing throughout pregnancy to the end of the first year of life. During this critical period, exposure to maternal lifestyle factors, specifically, prenatal smoking can negatively affect the quality (i.e., tooth calcification and mineralization) and timing of tooth eruption. Methods: This study evaluated the association between the trimester of smoking and offspring caries experience at 3 time points (31, 43, and 61 months) by analyzing data from 1,429 mother-offspring participants in the 1991/92 Avon Longitudinal Study of Parents and Children, conducted in Bristol, England. Prenatal smoking in the first, second, and third trimesters were self-reported during pregnancy while offspring caries experience was determined by clinical oral examinations. Adjusted for confounders, log-binomial regression estimated the risk ratio (RR) and 95% confidence interval (CI) of the association between trimester of smoking and the risk of offspring caries. Results: Twenty percent smoked in the first trimester of their pregnancy, 15% in the second, and 17% in the third. Forty-six percent of children whose mothers smoked during pregnancy had caries experience (i.e., dmft ≥1) with a mean dmft count of 1.58, versus children whose mothers did not smoke during pregnancy (33% of whom had dmft ≥1 with a mean dmft count of 0.33). Smoking in the first, second, and third trimesters were independently associated with a higher adjusted RR (95% CI) of caries experience at 61 months, i.e., 1.16 (0.93–1.43), 1.11 (0.75–1.65), and 1.60 (1.09–2.32), respectively. Conclusions: Within the limitations of covariates adjusted for, with the caveat that residual confounding and bias from unmeasured covariates are likely present, our findings suggest that smoking during pregnancy may be harmful to the oral health of the offspring irrespective of the trimester during which the smoking occurred. Nevertheless, these results should be interpreted cautiously because the findings might not generalize broadly.

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“…The cohort did not include 3296 stillbirths. schizophrenia and delusional disorder, personality disorder and drug-or alcohol-related substance use disorders (see 18 We identified mental disorders that were present during pregnancy using diagnostic codes from the delivery discharge abstract, which contains information on any prenatal mental disorder that required ambulatory treatment. 19 We also had information on mental disorders that required hospitalization before pregnancy.…”

Section: Methodsmentioning

confidence: 99%

“…The primary exposure in this study was any maternal mental disorder diagnosed before or during pregnancy, including depression, bipolar disorder, stress- and anxiety-related disorders, schizophrenia and delusional disorder, personality disorder and drug- or alcohol-related substance use disorders (see Table, Supplemental Digital Content 1, http://links.lww.com/INF/E330 for International Classification of Diseases codes). 18 We identified mental disorders that were present during pregnancy using diagnostic codes from the delivery discharge abstract, which contains information on any prenatal mental disorder that required ambulatory treatment. 19 We also had information on mental disorders that required hospitalization before pregnancy.…”

Section: Methodsmentioning

confidence: 99%

“…Information on the cohort was available from hospital discharge abstracts compiled in the Maintenance and Use of Data for the Study of Hospital Clientele registry. 18 Discharge abstracts contain clinical information on up to 41 diagnoses coded using the International Classification of Diseases and 35 procedures coded using the Canadian Classification of Health Interventions. Infants are linked with their mothers in the registry, enabling us to obtain data on maternal exposures and morbidities.…”

Section: Methodsmentioning

confidence: 99%

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Maternal Mental Disorders and Pediatric Infectious Diseases

Auger

Monnier

Low

et al. 2021

Pediatric Infectious Disease Journal

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Background: Maternal stress and depression are associated with infections in offspring, but there is a paucity of data for other mental disorders. Methods: We conducted a retrospective cohort study of 832,290 children born between 2006 and 2016 in hospitals of Quebec, Canada. We identified maternal mental disorders before and during pregnancy, and admissions for otitis media, pneumonia, infectious enteritis and other infections in children before 13 years of age. We used Cox proportional hazards regression to estimate hazard ratios (HRs) with 95% confidence intervals (CI) for the association between maternal mental disorders and the risk of pediatric infectious diseases, adjusted for maternal age, comorbidity, socioeconomic disadvantage, and other confounders. Results: The incidence of pediatric infection hospitalization was higher for maternal mental disorders compared with no disorder (66.1 vs. 41.1 cases per 1000 person-years). Maternal mental disorders were associated with 1.38 times the risk of otitis media (95% CI: 1.35-1.42), 1.89 times the risk of bronchitis (95% CI: 1.68-2.12), and 1.65 times the risk of infectious enteritis in offspring (95% CI: 1.57-1.74). Stress and anxiety disorders (HR 1.49, 95% CI: 1.46-1.53) and personality disorders (HR 1.55, 95% CI: 1.49-1.61) were more strongly associated with the risk of pediatric infection hospitalization than other maternal mental disorders. Associations were prominent in the first year of life and weakened with age. Conclusions: Maternal mental disorders are risk factors for infectious disease hospitalization in offspring. Women with mental disorders may benefit from psychosocial support to reduce the risk of serious infections in their children.

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Prenatal Substance Use Disorders and Dental Caries in Children

Cited by 12 publications

References 34 publications

The importance of prenatal dental care: a concise systematic review

The importance of prenatal dental care: a concise systematic review

Does the Trimester of Smoking Matter in the Association between Prenatal Smoking and the Risk of Early Childhood Caries?

Maternal Mental Disorders and Pediatric Infectious Diseases

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