Prenatal psychosocial stress-induced behavioral and neuroendocrine abnormalities are associated with sex-specific alterations in synaptic transmission and differentially modulated by maternal environment
Abstract:Louis.Muglia@cchmc.org, phone: (513) 803-8040, fax: (513) 803-5009 3 ABSTRACT Prenatal stress (PS) is associated with increased vulnerability to affective disorders.Transplacental glucocorticoid passage and stress-induced maternal environment alterations are recognized as potential routes of transmission that can fundamentally alter neurodevelopment.However, molecular mechanisms underlying aberrant emotional outcomes or the individual contributions intrauterine stress versus maternal environment play in shapin… Show more
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