Prenatal intrarenal neuroblastoma mimicking a mesoblastic nephroma: a case report

Imaging and Differential Diagnosis of Suprarenal Masses in the Fetus

“…The displaced but otherwise normal adrenal glands can usually be distinctly identified as a separate entity from the sequestration. An extralobar pulmonary sequestration is also generally diagnosed earlier in pregnancy, more commonly in the second trimester, than a neuroblastoma, which is usually diagnosed in the third trimester 7 , 8 …”

“…An extralobar pulmonary sequestration is also generally diagnosed earlier in pregnancy, more commonly in the second trimester, than a neuroblastoma, which is usually diagnosed in the third trimester. 7,8 The MRI appearance of an extralobar pulmonary sequestration is characterized by a well-defined homogeneous mass with a high signal on T2-weighted imaging and a low signal on T1-weighted imaging ( Figure 6); the feeding arterial vessel may not be seen well with MRI. The appearance of an extralobar pulmonary sequestration on MRI can be difficult to differentiate from that of certain types of neuroblastomas; however, an extralobar pulmonary sequestration will typically be uniformly higher in signal than a neuroblastoma.…”

Tumors of the Adrenal Gland

“…Rarely, primary neuroblastoma can be found in the central nervous system (supratentorial primitive neuroectodermal tumor, see CNS Chap. 6 for detailed discussion) and within the kidney (mimicking mesoblastic nephroma [ 19 ]). In contrast, posterior mediastinum is the commonest site (41.5 %) for ganglioneuroma, followed by retroperitoneum (37.5 %), adrenal gland (21 %), and neck (8 %).…”

“…Finding an arterial supply from the thoracic aorta and stability of size are helpful in the differentiation from neuroblastoma. Other differential diagnoses of a suprarenal mass on prenatal ultrasound include a duplex collecting system with dysplastic changes, exophytic Wilms' tumor, mesoblastic nephroma [ 19 ], retroperitoneal teratoma, liver tumor, and splenic cyst [ 24 ]. Neuroblastic tumors in the pediatric abdomen and pelvis appear as solid masses of varying echogenicity and heterogeneity ( Fig.…”

Primary Renal Neuroblastoma Metastasizing into Liver and Lungs with Tumor Thrombus Extension into the Right Atrium

“…Garnier et al reported on a case of a prenatally diagnosed tumor within the left kidney. Histopathological analysis of postnatal nephrectomy revealed a neuroblastoma, later staged as 4-S [ 3 ] . In a British case report dating back to 2006, the authors report on a 9-month-old boy, suff ering from abdominal pain and distended abdomen.…”