Prenatal intestinal histology and histochemistry in the goat

Abstract

The mucosa of the small and large intestine of goat fetuses exhibited villi which had disappeared after the 32.5-cm curved crown rump (CVR) stage. At places, the stratified epithelial lining persisted among the normal columnar epithelium with goblet cells. The concentration of goblet cells increased with age, while the thickness of the epithelium decreased. The crypts of Lieberkühn were tortuous at the base. Brunner’s glands appeared at the 14.2-cm CVR stage. Peyer’s patches appeared at the 24.5-cm CVR stage in the ileum. The muscularis mucosae differentiated in the large intestine in group II (16.2- to 24.5-cm CVR length) and progressed caudocranially. The striated border of the intestinal epithelium presented with alkaline phosphatase activity; this border and the goblet cells also stained for mucin. Glycogen was demonstrable in the epithelium with greater concentrations in the duodenum and jejunum in group I (11.5-to 14.6-cm CVR length), and in the ileum and large intestine in group III (30.8-to 39.5-cm CVR length).

Embryonic differentiation of intestine in Indian goats (Capra hircus)

“…Alkaline phosphatase localized in the brush border membrane of intestine might be correlated with role in the absorption of cholesterol, lipid, vitamin D, calcium, amino acids, and glucose (Şensoy & Oznurlu, 2019). No acid phosphatase activity was noticed in any segment of intestine up to end of early prenatal period which was in full agreement with Ramkrishna and Tiwari (1979) in goat. The less occurrence of acid phosphatase enzyme might be correlated with intracellular digestive activity of intestinal epithelium before birth.…”

“…The presence of lipids found in this investigation could be correlated the lipids provide most concentrated energy resource to the cell and they are essential component of cell membrane. The luminal border of epithelial cells and mesothelium took mild to moderate alkaline phosphatase reaction which was in agreement with Ramkrishna and Tiwari (1979) in goat feti and Şensoy and Oznurlu (2019) in Swiss albino mice. Intestinal alkaline phosphatase has an important role in gut mucosal defence (Fawley and Fawley & Gourlay, 2016).…”

“…In buffalo feti the undifferentiated layer of muscle fibres was noticed at 47th day (Singh et al, 2009) and at 53rd day (Malhotra, 2002); this layer got differentiated into inner circular and outer longitudinal smooth muscles layer at 119th day (Singh et al, 2009) and at 117th day of gestation (Malhotra, 2002), respectively. In present study the inner circular smooth muscles layer was thicker than outer longitudinal layer as noticed by Ramkrishna and Tiwari (1979) in goat and Singh et al (2009) in buffalo feti. In small intestine and caecum, the tunica serosa was composed of mesothelium only whereas in colon and rectum, mesothelium supported by loose connective tissue also.…”