Prenatal exposures to mixtures of endocrine disrupting chemicals and sex-specific associations with children’s BMI and overweight at 5.5 years of age in the SELMA study

Svensson, Katherine; Gennings, Chris; Lindh, Christian; Kiviranta, Hannu; Rantakokko, Panu; Wikström, Sverre; Bornehag, Carl-Gustaf

doi:10.1016/j.envint.2023.108176

Cited by 8 publications

(1 citation statement)

References 78 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Research has demonstrated that pesticides can permeate both the placental barrier and the fetal blood–brain barrier, thereby impacting the developing fetus when the mother is exposed ( 233 ). Given the potential long-term health implications in both childhood and adulthood stemming from early exposure to environmental contaminants during pregnancy, it is imperative to conduct longitudinal studies to obtain meaningful and significant results ( 234 ). These findings add to the mounting evidence indicating that exposure to environmental contaminants during early life can hinder proper development ( 235 ).…”

Section: Applicationsmentioning

confidence: 99%

Determination of pesticide residues in urine by chromatography-mass spectrometry: methods and applications

Birolli,

Lanças,

dos Santos Neto

et al. 2024

Front. Public Health

View full text Add to dashboard Cite

IntroductionPollution has emerged as a significant threat to humanity, necessitating a thorough evaluation of its impacts. As a result, various methods for human biomonitoring have been proposed as vital tools for assessing, managing, and mitigating exposure risks. Among these methods, urine stands out as the most commonly analyzed biological sample and the primary matrix for biomonitoring studies.ObjectivesThis review concentrates on exploring the literature concerning residual pesticide determination in urine, utilizing liquid and gas chromatography coupled with mass spectrometry, and its practical applications.MethodThe examination focused on methods developed since 2010. Additionally, applications reported between 2015 and 2022 were thoroughly reviewed, utilizing Web of Science as a primary resource.SynthesisRecent advancements in chromatography-mass spectrometry technology have significantly enhanced the development of multi-residue methods. These determinations are now capable of simultaneously detecting numerous pesticide residues from various chemical and use classes. Furthermore, these methods encompass analytes from a variety of environmental contaminants, offering a comprehensive approach to biomonitoring. These methodologies have been employed across diverse perspectives, including toxicological studies, assessing pesticide exposure in the general population, occupational exposure among farmers, pest control workers, horticulturists, and florists, as well as investigating consequences during pregnancy and childhood, neurodevelopmental impacts, and reproductive disorders.Future directionsSuch strategies were essential in examining the health risks associated with exposure to complex mixtures, including pesticides and other relevant compounds, thereby painting a broader and more accurate picture of human exposure. Moreover, the implementation of integrated strategies, involving international research initiatives and biomonitoring programs, is crucial to optimize resource utilization, enhancing efficiency in health risk assessment.

show abstract

Section: Applicationsmentioning

confidence: 99%