Prenatal Exposure to Mercury and Fish Consumption During Pregnancy and Attention-Deficit/Hyperactivity Disorder–Related Behavior in Children

Sagiv, Sharon K.; Thurston, Sally W.; Bellinger, David C.; Amarasiriwardena, Chitra; Korrick, Susan A.

doi:10.1001/archpediatrics.2012.1286

Cited by 155 publications

(114 citation statements)

References 50 publications

Supporting

Mentioning

102

Contrasting

Unclassified

Order By: Relevance

“…14 While prenatal mercury exposure (1 mcg/g or greater) was found to be associated with a greater risk of attention-deficit hyperactivity disorder-related behaviors, prenatal fish consumption of more than two servings per week was protective of those behaviors. 33 RDNs and dietetic technicians, regsitered can help pregnant women balance the benefits of eating fish while avoiding high-mercury content seafood.…”

Section: Environmental and Dietary Issuesmentioning

confidence: 99%

Position of the Academy of Nutrition and Dietetics: Nutrition and Lifestyle for a Healthy Pregnancy Outcome

Procter

Campbell

2014

Journal of the Academy of Nutrition and Dietetics

170

134

View full text Add to dashboard Cite

Section: Environmental and Dietary Issuesmentioning

confidence: 99%

Position of the Academy of Nutrition and Dietetics: Nutrition and Lifestyle for a Healthy Pregnancy Outcome

Procter

Campbell

2014

Journal of the Academy of Nutrition and Dietetics

170

134

View full text Add to dashboard Cite

“…Outcomes can be classified as pertaining to cognitive, behavioral, or general developmental areas. Cognitive outcomes were ascertained by using VRM (Visual Recognition Memory) [22], WISC (Wechsler Intelligence Scale for Children) [10,17,25,27 [19,20]. Behavioral outcomes were measured by the SDQ (Strengths and Difficulties Questionnaire) [10,25], CRS-T (Conner's Rating Scale-Teacher's version) [27•], and the YSR (Youth Self-Report) [19].…”

Section: Study Characteristicsmentioning

confidence: 99%

“…Common covariates were child age [15, 19, 22-24, 27•, 28], sex [1, 10, 15, 16, 19, 22-24, 26, 27•], and breastfeeding [1, 10, 15, 16, 18•, 22-25], as well as maternal age [10, 15, 16, 22, 24, 25, 27•, 28], sociodemographic characteristics [1, 10, 15-17, 18•, 19, 21-26, 27•], smoking [10, 15-17, 18•, 24-26, 27•], and alcohol use [10,15,[24][25][26]27•]. Of special interest, seven articles also reported having adjusted in some way for the possible effects of contaminants such as mercury [15, 18•, 22, 24, 26, 27•] or persistent organic pollutants [1,26,27•] (Table 3).…”

Section: Study Characteristicsmentioning

confidence: 99%

“…Of special interest, seven articles also reported having adjusted in some way for the possible effects of contaminants such as mercury [15, 18•, 22, 24, 26, 27•] or persistent organic pollutants [1,26,27•] (Table 3). In some but not all studies, adjusting for mercury and/or POPs further strengthened the positive association between seafood intake and neurodevelopmental outcomes.…”

Section: Study Characteristicsmentioning

confidence: 99%

See 1 more Smart Citation

Seafood Intake and Neurodevelopment: A Systematic Review

Garcia-Esteban

Júlvez

2014

Curr Envir Health Rpt

View full text Add to dashboard Cite

Exposure to fish intake is of particular interest for neurodevelopment. Seafood contains nutrients that are essential for brain development and function. Seafood is also a potential source of well-established neurotoxic pollutants. We conducted a systematic search of the literature to review human studies on seafood intake and neurodevelopment. We identified 16 studies, most of them prospective cohort studies with prenatal and postnatal seafood intake exposure assessed through food frequency questionnaires. Most studies found positive associations with neurodevelopment outcomes, without particularly stronger associations for specific developmental areas (general, cognitive, and behavioral). Some studies observed an inverted U-shape association in relation with higher seafood-intake frequency. A few reports assessed type of seafood but no clear pattern was disentangled. In conclusion, seafood intake during pregnancy and postnatal periods seems to be beneficial to a wide range of neurodevelopment outcomes, with some potential risk at higher levels. Although studies adjusted for a variety of sociodemographic factors, residual confounding is possible. Larger prospective studies are required to define which seafood species are more important for neurodevelopment while minimizing the potential neurotoxic effect of the related pollutants.

show abstract

“…The median PCB concentrations in Cohorts 1 and 3 were higher than among American adults in the NHANES 2001–2002 data and among women delivering in two eastern Slovakian areas in 2002–2004, whereas, in Cohort 5, the median PCB concentration was higher than in NHANES, but lower than in one of the two Slovakian areas [39,40]. The median hair mercury concentrations among the Faroese women were higher than in a 1993–1998 cohort of new mothers from Massachusetts, US [41] and the median hair mercury concentrations in Cohorts 1 and 3 were also higher than among a group of Japanese mothers examined in 2002–2003, but in Cohort 5 the median hair mercury concentration was lower than among the Japanese mothers [42]. …”

Section: Discussionmentioning

confidence: 99%

Secondary sex ratio in relation to exposures to polychlorinated biphenyls, dichlorodiphenyl dichloroethylene and methylmercury

Timmermann¹,

Choi

Petersen

et al. 2017

International Journal of Circumpolar Health

View full text Add to dashboard Cite

This study was undertaken to assess the potential impact of maternal exposures to polychlorinated biphenyl (PCB), dichlorodiphenyl dichloroethylene (DDE) and methylmercury on the secondary sex ratios (the ratio of male to female live births) over a span of 23 years. The study includes prospective data from three Faroese birth cohorts, with a total of 2,152 healthy mother–child dyads recruited between 1986 and 2009. The Faroe Islands is a subarctic fishing community, where pilot whale meat and blubber are part of the traditional marine diet. Exposures were measured in maternal hair, serum or umbilical cord blood. Confounder adjusted logistic regression models were used to assess the associations between maternal exposures and the secondary sex ratio. A doubling in ΣPCB, p,p’-DDE and mercury concentrations were associated with increased odds by 8% (95% CI = 0–16%), 7% (95% CI = 0–14%) and 9% (95% CI = 2–17%), respectively, of giving birth to a boy. In conclusion, maternal exposure to ΣPCB, DDE and methylmercury was associated with a slightly increased secondary sex ratio. The impact of paternal exposures could not be taken into account and deserves attention.

show abstract

Prenatal Exposure to Mercury and Fish Consumption During Pregnancy and Attention-Deficit/Hyperactivity Disorder–Related Behavior in Children

Cited by 155 publications

References 50 publications

Position of the Academy of Nutrition and Dietetics: Nutrition and Lifestyle for a Healthy Pregnancy Outcome

Position of the Academy of Nutrition and Dietetics: Nutrition and Lifestyle for a Healthy Pregnancy Outcome

Seafood Intake and Neurodevelopment: A Systematic Review

Secondary sex ratio in relation to exposures to polychlorinated biphenyls, dichlorodiphenyl dichloroethylene and methylmercury

Contact Info

Product

Resources

About