Prenatal and postnatal risk factors for developing bronchopulmonary dysplasia

Gantar, Irena Štucin; Babnik, J.; Cerar, Lilijana Kornhauser; Šinkovec, Jasna; Wraber, Branka

doi:10.22514/sv62.102011.6

Cited by 6 publications

(4 citation statements)

References 38 publications

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“…Six studies provided BPD outcomes for infants with histologic and clinical CA separately. 68,75,80,116,127,146 One study required infants to have both histologic and clinical CA to be considered exposed to CA. 84 Nine studies defined CA using a microbiological definition.…”

Section: Resultsmentioning

confidence: 99%

“…Of 3170 potentially relevant studies, 158 (5.0%) met the inclusion criteria. The PRISMA flow diagram of the search process is shown in Figure 1.…”

Section: Resultsmentioning

confidence: 99%

“…Seventy-six studies were designed from the perspective of CA; they examined the outcomes of preterm infants with or without CA, and BPD was one of these outcomes. Sixty-seven studies were designed from the perspective of BPD; they studied risk factors for BPD, and CA was one of these risk factors. Sixteen studies were designed to primarily examine the association between CA and BPD.…”

Section: Resultsmentioning

confidence: 99%

“…Forty-two studies defined CA clinically, and 97 studies defined CA histologically. Six studies provided BPD outcomes for infants with histologic and clinical CA separately . One study required infants to have both histologic and clinical CA to be considered exposed to CA .…”

Section: Resultsmentioning

confidence: 99%

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Association of Chorioamnionitis With Bronchopulmonary Dysplasia Among Preterm Infants

et al. 2019

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Key PointsQuestionIs chorioamnionitis a risk factor for developing bronchopulmonary dysplasia in preterm infants?FindingsThis systematic review, meta-analysis, and metaregression found that chorioamnionitis was associated with an increased risk of bronchopulmonary dysplasia in preterm infants but also found significant differences in baseline characteristics between infants with and infants without chorioamnionitis. A multivariate metaregression model combining the difference in gestational age and the odds of respiratory distress syndrome was associated with 64% of the variance in the association between chorioamnionitis and bronchopulmonary dysplasia.MeaningExposure to chorioamnionitis is associated with a higher risk of developing bronchopulmonary dysplasia in preterm infants, but this association may be modulated by gestational age and risk of respiratory distress syndrome.

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