Prenatal and Maternal Outcomes in Advanced Maternal Age, a Comparative Study

Yazdani, Maryam; Amirshahi, Elnaz; Shakeri, Aria; Amirshahi, Reza; Malekmakan, Leila

doi:10.17795/whb-23092

Cited by 8 publications

(9 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…After controlling for possible confounders, hypertensive disorder (pre-eclampsia and eclampsia syndrome, gestational, and chronic hypertension) signi cantly associated with advanced maternal age. This was congruent with studies conducted in Iran [29], Israel [21], and South Australia [30]. Similarly, as maternal age increased above 35 years old was signi cantly increased miscarriage.…”

Section: Association Of Maternal Age With Adverse Obstetric Outcomessupporting

confidence: 87%

“…Advanced maternal age was not signi cantly associated with cesarean mode of delivery as shown in this study. This was contradicted by different studies conducted in Iran [29], South Korea [20], Israel [21], Sweden [32], United Kingdom [17], South Australia [30], and a high-income developing country [31]. This may be a difference in the health care delivery system, socio-economic factors, and methodological variations.…”

Section: Association Of Maternal Age With Adverse Obstetric Outcomesmentioning

confidence: 98%

“…This was higher than studies conducted in Israel (2.3% and 14%) [4,10], Malaysia (14.8%) [14], WHO Multicountry Survey (12.8%) [9], Northeastern Brazil (5.9%) [13], Nepal (4.53%) [15], South Africa (17.5%) [16], and United Kingdom (18.18%) [17]. However, it was lower than studies done in Iran (50.2%) [29], and Norway (33.4%) [11]. This discrepancy may be due to differences in socio-demographic, and economic characteristics, technological and health care system, social, and cultural factors that lead to delayed childbearing or having pregnant at an advanced age.…”

Section: Association Of Maternal Age With Adverse Obstetric Outcomesmentioning

confidence: 99%

See 2 more Smart Citations

Adverse Obstetric Outcomes at Advanced Maternal Age in Arba Minch Zuria, and Gacho Baba District, Southern Ethiopia: A Prospective Cohort Study

Mersha¹,

Ayele²,

Worku³

et al. 2020

Preprint

View full text Add to dashboard Cite

Background: Advanced maternal age significantly increased the risk of adverse obstetric outcomes. So, adequate and updated information on the status of advanced maternal age and their effect on obstetric outcomes is vital for effective policy and program formulation in Ethiopia. Pockets of studies conducted, but most are retrospective and record reviews. Thus, studies that show the status of advanced maternal age and their effect on obstetric outcomes is very limited in Ethiopia. As such, this study fills those gaps in our set up.Methods: A community-based prospective cohort study was conducted among 709 study participants from October 15, 2018, to September 30, 2019. A pretested interviewer-administered structured Open Data Kit survey tool was used to collect the data. The downloaded data from the Open Data Kit aggregate was exported to SPSS version 25 for analysis. Log-linear regression was used to compare obstetric outcomes among women aged 20–34 years and ≥ 35 years. The model was adjusted for educational and occupational status, party, wealth index, body mass index, household food insecurity, habits, distance to health care institution, and sex of the neonate, antenatal care, postnatal care, and place of delivery. The model fitness was tested by the log-likelihood ratio.Results: In this study, 209(29.5%) of the women were aged ≥ 35 years, and 500(70.5%) aged 20–34 years. Women aged ≥ 35 years were at increased risk of miscarriage (β = 0.29, 95%CI: 0.02, 0.56), and hypertensive disorder (β = 0.07, 95%CI: 0.004, 0.13).Conclusions: Advanced maternal age was independently associated with miscarriage and hypertensive disorder after controlling for possible cofounders. As such, different intervention programs should be designed to create awareness and to provide counseling services for women with advanced age or delayed childbearing.Plain English summaryWomen who bear a child at the age of ≥35 years old are stated as advanced maternal age. At this age, the risk of different obstetric complications is increased. This study was aimed to assess the effect of advanced maternal age on obstetric outcomes in the study settings.A prospective follow-up study was conducted among pregnant women during the study period. The women were followed from the time pregnancy was confirmed up to the immediate postpartum period. Seven hundred forty-four women were interviewed in the baseline and 24 participants became lost to follow-ups during the follow-up period, and 11 excluded from the analysis because of incomplete information.Of the study participants, 209 of the women were beard children at the age of ≥35 years (advanced maternal age), and 500 were age group from 20-34 years old.This study found that advanced maternal age increased risk of miscarriage (termination of pregnancy before fetal viability) and hypertensive disorder during pregnancy, the intrapartum and immediate postpartum period after controlled for possible confounders.In brief, this study showed that a significant number of women became pregnant during advanced maternal age. Therefore, different strategies should be designed for the women who planned to bear child, and information should be provided for women who are advanced age or delayed childbearing to alert them.

show abstract

Section: Association Of Maternal Age With Adverse Obstetric Outcomessupporting

confidence: 87%

Section: Association Of Maternal Age With Adverse Obstetric Outcomesmentioning

confidence: 98%

Section: Association Of Maternal Age With Adverse Obstetric Outcomesmentioning

confidence: 99%

See 1 more Smart Citation

Adverse Obstetric Outcomes at Advanced Maternal Age in Arba Minch Zuria, and Gacho Baba District, Southern Ethiopia: A Prospective Cohort Study

Mersha¹,

Ayele²,

Worku³

et al. 2020

Preprint

View full text Add to dashboard Cite

show abstract

“…Belated marriage, a higher level of education, career pursuit, increased life expectancy, contraceptive use, labor market participation, economic uncertainty and value changes were the main reasons for delayed childbearing [11][12][13]. On the contrary, some studies indicated that multiparous women continuing childbearing to advanced maternal age because of ignorance, low use of contraceptive methods, and remarriage [14,15].…”

Section: Introductionmentioning

confidence: 99%

Association between maternal age and adverse perinatal outcomes in Arba Minch zuria, and Gacho Baba district, southern Ethiopia: a prospective cohort study

Mersha

Ayele

Worku

et al. 2020

BMC Pregnancy Childbirth

View full text Add to dashboard Cite

Background Globally, delayed childbearing to the advanced age is a growing option. It is an emerging public health issue in developing countries. Currently, adverse perinatal outcomes significantly increased. A few studies showed the effect of advanced maternal age on adverse perinatal outcomes. However, most used secondary data or chart reviews, and this increases the risk of biases. Besides, there are limited studies in-country Ethiopia as advanced maternal age steadily increased. Therefore, this study aimed to assess the status of advanced maternal age and its effect on perinatal outcomes in the study setting. Methods A community-based prospective cohort study was conducted among 709 study participants from October 15, 2018, to September 30, 2019, in Arba Minch zuria, and Gacho Baba district, southern Ethiopia. The data were collected by a pretested interviewer-administered structured Open Data Kit survey tool and analyzed by SPSS version 25. The log-linear regression model was used to compare perinatal outcomes among women aged 20–34 years and ≥ 35 years. The log-likelihood ratio tested for the goodness of fit. In this study, P-value < 0.05 was considered to declare a result as a statistically significant association. Results In this study, 209(29.5%) of the women were age group ≥35 years old, and 500(70.5%) were age group from20–34 years old. Stillbirth (β = 0.29, 95%CI: 0.05, 0.52), and neonatal mortality (β = 0.11, 95%CI: 0.01, 0.21) were significantly associated with the advanced maternal age. Conclusions Perinatal outcomes such as stillbirth and neonatal mortality were independently associated with advanced maternal age after controlling for possible cofounders. Therefore, different strategies should design for the women who planned to bear child, and information should provide for women who are advanced age or delayed childbearing to alert them.

show abstract

“…A study in Iran found that the incidence rate of preeclampsia was also the highest in age group >35 years, as much as 76.4% than other age groups. 7 In pregnant women less than 20 years of age and 35 years of age or older the reproductive organs are not ready for pregnancy so that those ages are more at risk for preeclampsia. According to Rochjati, susceptibility to preeclampsia is due to changes in the uterine tissue and birth canal, 8 in addition to an increase in blood pressure with age.…”

Section: Resultsmentioning

confidence: 99%

Difference of calcium levels in Javanese, Madurese, and Chinese preeclamptic women

Wulandari

Ernawati

Akbar

2018

MOG

View full text Add to dashboard Cite

Objectives: To analyse difference of calcium levels and charac-teristics between Javanese, Madurese, and Chinese pre-eclamptic women that affects preeclampsia incidence.Materials and Methods: This was a cross-sectional study with preeclamptic patients in Dr. Soetomo Hospital, Dr. M. Soewan-dhie Hospital, and Universitas Airlangga Hospital as sample. Sample was taken by measuring total calcium level in blood serum before receiving MgSO4 using in vitro clinical chemical dimension method in the Laboratory of Clinical Pathology in Dr. Soetomo Hospital. Sample was taken using consecutive sampling. Sample size 53 preeclamptic women as participants of this study, divided into three groups of Javanese, Madurese, and Chinese.Results: There were 53 preeclampsia patients, with mean ages: Javanese 31.21±5.76, Madurese 34.20±5.58, and Chinese 28.20 ±2.16. Mean BMI: Javanese 31.19±5.99, Madurese 27.66±4.74, and Chinese 26.24±2.13. We found significant difference in total calcium levels. In Madurese it was 7.7 mg/dL, Javanese was 8.3 mg/dL, and Chinese was 9.0 mg/dL (p=.000).Conclusion: The highest severity of preeclampsia was in the Madurese with low calcium levels. The lowest the calcium level, the worst the severity of the preeclampsia.

show abstract

Prenatal and Maternal Outcomes in Advanced Maternal Age, a Comparative Study

Cited by 8 publications

References 16 publications

Adverse Obstetric Outcomes at Advanced Maternal Age in Arba Minch Zuria, and Gacho Baba District, Southern Ethiopia: A Prospective Cohort Study

Adverse Obstetric Outcomes at Advanced Maternal Age in Arba Minch Zuria, and Gacho Baba District, Southern Ethiopia: A Prospective Cohort Study

Association between maternal age and adverse perinatal outcomes in Arba Minch zuria, and Gacho Baba district, southern Ethiopia: a prospective cohort study

Difference of calcium levels in Javanese, Madurese, and Chinese preeclamptic women

Contact Info

Product

Resources

About