Premenstrual syndrome: rational approaches to non-hormonal therapy

Abstract

The objective: is the development of rational effective methods of non-hormonal therapy of premenstrual syndrome. Materials and methods. Under observation, there were 35 women 23-38 years aged. The diagnosis of premenstrual syndrome was established on the basis of general clinical, laboratory, instrumental research methods and consultancy by psychologist and psychiatrist. Evaluation of the effectiveness of treatment was carried out according to PMS-diaries by comparing the intensity of 18 symptoms expressed in points in the dynamics of treatment. For the purpose of correcting the symptoms of premenstrual syndrome, drug therapy was proposed, which in addition to antiprostaglandins according to the traditional scheme included venentonic Normoven, magnesium preparations (Magnikum), herbal teas. Treatment was carried out during II phase in the course of 3 menstrual cycles. Results. It was found that the average total index of PMS-diaries before the start of treatment was 23.4±6.7 points, after treatment – 10.1±7.2 points. A positive effect of treatment after 1 month was recorded by 28.6% of respondents, after the ending of treatment the share of respondents was 68.6%, the average total PMS-diary index decreased by 40% or more in comparing with the initial data. According to CINM-questionnaires: after 3 months of treatment 20 (57.1%) patients showed significant improvement, 15 (42.9%) women without significant changes.. Conclusion. Studies have shown that the treatment of premenstrual syndrome should be individualized. However, the use of such medications as magnesium lactate (Magnikum), Normoven venotonics allows to increase the effectiveness of the therapy of premenstrual syndrome in 68.8% of patients. Key words: premenstrual syndrome, non-hormonal therapy.