Premature rupture of membranes at term in low risk women: how long should we wait in the “latent phase”?

Pintucci, Armando; Meregalli, Virginio; Colombo, P.C.; Fiorilli, Angelo

doi:10.1515/jpm-2013-0017

Cited by 18 publications

(6 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Five studies in relation to PROM were included, consisting of two Cochrane reviews [81,82], one prospective cohort study [83], and two retrospective cohort studies [84,85]. One Cochrane review and three studies addressed PROM at term (37-42 weeks) [81,[83][84][85], whilst the other Cochrane review addressed preterm PROM (<37 weeks) [82]. In relation to preterm PROM (< 37 weeks), the Cochrane review by Bond et al [82] compared outcomes associated with women undergoing a planned early birth (by IOL or CS) with EM between 24 and 37 weeks.…”

Section: Premature Rupture Of Membranes (Prom)mentioning

confidence: 99%

A systematic scoping review of clinical indications for induction of labour

Coates¹,

Makris²,

Catling³

et al. 2020

PLoS ONE

View full text Add to dashboard Cite

Background The proportion of women undergoing induction of labour (IOL) has risen in recent decades, with significant variation within countries and between hospitals. The aim of this study was to review research supporting indications for IOL and determine which indications are supported by evidence and where knowledge gaps exist. Methods A systematic scoping review of quantitative studies of common indications for IOL. For each indication, we included systematic reviews/meta-analyses, randomised controlled trials (RCTs), cohort studies and case control studies that compared maternal and neonatal outcomes for different modes or timing of birth. Studies were identified via the databases PubMed, Maternity and Infant Care, CINAHL, EMBASE, and ClinicalTrials.gov from between April 2008 and November 2019, and also from reference lists of included studies. We identified 2554 abstracts and reviewed 300 full text articles. The quality of included studies was assessed using the RoB 2.0, the ROBINS-I and the ROBIN tool. Results 68 studies were included which related to post-term pregnancy (15), hypertension/preeclampsia (15), diabetes (9), prelabour rupture of membranes (5), twin pregnancy (5), suspected fetal compromise (4), maternal elevated body mass index (BMI) (4), intrahepatic cholestasis of pregnancy (3), suspected macrosomia (3), fetal gastroschisis (2), maternal age (2), and maternal cardiac disease (1). Available evidence supports IOL for women with post-term pregnancy, although the evidence is weak regarding the timing (41 versus 42

show abstract

Section: Premature Rupture Of Membranes (Prom)mentioning

confidence: 99%

A systematic scoping review of clinical indications for induction of labour

Coates¹,

Makris²,

Catling³

et al. 2020

PLoS ONE

View full text Add to dashboard Cite

show abstract

“…Preterm PROM is a major complication of pregnancy [25–39], and accounts for 30% of spontaneous preterm births [40–42]. Microorganisms in the amniotic fluid are present in approximately 30% of patients, based on the results of culture techniques [43–66], and in 50% of patients using the combination of culture and molecular microbiologic techniques [67–72].…”

Section: Introductionmentioning

confidence: 99%

A new antibiotic regimen treats and prevents intra-amniotic inflammation/infection in patients with preterm PROM

Lee

Romero

Kim

et al. 2015

The Journal of Maternal-Fetal & Neonatal Medicine

View full text Add to dashboard Cite

Objective To determine if a new antibiotic regimen could reduce the frequency of intra-amniotic inflammation/infection in patients with preterm PROM. Study design This retrospective cohort study was conducted to evaluate the effect of antibiotics on the frequency of intra-amniotic inflammation/infection based on the results of follow-up transabdominal amniocenteses from 89 patients diagnosed with preterm PROM who underwent serial amniocenteses. From 1993–2003, ampicillin and/or cephalosporins or a combination was used (“regimen 1”). A new regimen (ceftriaxone, clarithromycin, and metronidazole) was used from 2003–2012 (“regimen 2”). Amniotic fluid was cultured and matrix metalloproteinase-8 (MMP-8) concentrations were measured. Results 1) The rates of intra-amniotic inflammation and intra-amniotic inflammation/infection in patients who received regimen 2 decreased during treatment from 68.8% to 52.1% and from 75% to 54.2%, respectively. In contrast, in patients who received regimen 1, the frequency of intra-amniotic inflammation and infection/inflammation increased during treatment (31.7% to 55% and 34.1% to 58.5%, respectively); and 2) intra-amniotic inflammation/infection was eradicated in 33.3% of patients who received regimen 2, but in none who received regimen 1. Conclusion The administration of ceftriaxone, clarithromycin, and metronidazole was associated with a more successful eradication of intra-amniotic inflammation/infection and prevented secondary intra-amniotic inflammation/infection more frequently than an antibiotic regimen which included ampicillin and/or cephalosporins in patients with preterm PROM.

show abstract

“…And the rates are higher in earlier gestational ages. Pintucci et al reported 2.3% clinical chorioamnionitis rate at term premature rupture of membranes (16). The rates are higher with lower gestational ages.…”

Section: Discussionmentioning

confidence: 96%

Changes in Umbilical and Cerebral Blood Flow in Pregnancies Diagnosed with Clinical Chorioamnionitis. Is Chorioamnionitis Predictable?

Ozkan¹,

Ekmekçi²

2019

Gynecol Obstet Reprod Med

View full text Add to dashboard Cite

Objective: To evaluate the predictability of clinical chorioamnionitis by Doppler changes in fetal middle cerebral and umbilical arteries, at hospitalized patients due to preterm premature rupture of membranes.Study Design: Patients who were admitted and hospitalized due to preterm premature rupture of membranes between 24 weeks and 33 weeks and 6 days pregnancies are included in the study. Demographic data of patients, gestational age at referring to hospitalization, fetal presentation at admission, delivery time, delivery indications and total follow-up time until delivery of each case were recorded.Results: A total of 108 patients were evaluated retrospectively. The rate of clinical chorioamnionitis was 5.55% (6/108). There was no significant difference between pregnancies terminated with the diagnosis of clinical chorioamnionitis and pregnancies terminated with other indications in terms of the maximum systolic velocity at middle cerebral artery and umbilical artery pulsatility indices.Conclusion: Clinical chorioamnionitis is a serious complication and is more common in patients being followed up after preterm premature rupture of membranes. Although it is crucial to be predicted due to neonatal worse prognosis, it cannot be predicted by middle cerebral and umbilical artery Doppler evaluation.

show abstract

Premature rupture of membranes at term in low risk women: how long should we wait in the “latent phase”?

Abstract: Fetal and/or maternal morbidity in tPROM women may not increase if there is a strict analysis of maternal and or fetal risk factors added to a careful clinical management. Moreover, it may be useful to wait for spontaneous labor in order to enhance the patient's chance of vaginal delivery.

Cited by 18 publications

References 4 publications

A systematic scoping review of clinical indications for induction of labour

A systematic scoping review of clinical indications for induction of labour

A new antibiotic regimen treats and prevents intra-amniotic inflammation/infection in patients with preterm PROM

Changes in Umbilical and Cerebral Blood Flow in Pregnancies Diagnosed with Clinical Chorioamnionitis. Is Chorioamnionitis Predictable?

Contact Info

Product

Resources

About