Premature pubarche in Prader‐Willi syndrome: Risk factors and consequences
Emily Griffing,
Kelsee Halpin,
Brian R. Lee
et al.
Abstract:ObjectivesChildren with Prader‐Willi Syndrome (PWS) may develop premature pubarche (PP). We investigated the frequency of PP, and its potential precursors and sequelae, in PWS.Design, Patients and MeasurementsA chart review of children with PWS treated at our institution between 1990 and 2021 was performed. PP was defined as Tanner stage 2 (TS2) pubic hair in girls <8 and boys <9 years old. Demographic, anthropometric, and laboratory data were collected to assess predisposing factors and consequences of … Show more
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