Preliminary study on the osseointegration effects of contactless automated implant cavity preparation via femtosecond laser ablation

Abstract

Microrobots were used to control the femtosecond laser ablation of bone tissues to prepare implant cavities for dental implant surgery. The method was optimized through depth-of-cut experiments of ex vivo rabbit femurs, and the optimized method was used to prepare implant cavities on the left femurs of eight live rabbits. A power of 10 W and a scanning rate of 4000 mm/s were found to be optimal. After seven days of osteoinduction, the expression of collagen type I was significantly higher in the experimental group than in the control group (manually drilled implant cavities). The bone–implant contacts of the experimental group at 4 and 8 weeks were 9.65% and 23.08%, respectively.

High-speed, long-range and wide-field OCT for in vivo 3D imaging of the oral cavity achieved by a 600 kHz swept source laser

“…Since its inception, optical coherence tomography (OCT) has undergone remarkable progress, evolving from time-domain to spectral-domain configurations and, more recently, embracing the sophisticated swept-source OCT (SS-OCT) [ 1 – 3 ]. These continuous technological innovations have firmly established OCT as an indispensable tool in various biomedical imaging applications, spanning clinical fields such as ophthalmology [ 4 – 7 ], dentistry [ 8 – 12 ], dermatology [ 13 – 17 ], endoscopy [ 18 – 23 ], neuroscience [ 24 – 27 ], and more.…”

Image monitoring of femtosecond laser processing of biological hard tissue with a simple mobile phone camera

“…Due to the physical extrusion and thermal effect, there are risks of mechanical and thermal damages in the traditional osteotomy and dental surgery [1,2]. In comparison with the mechanical processing, laser processing of the hard tissues is proposed as a highly potential alternative due to its unique characteristics of non-contact processing, high precision, low thermal damage and so on [3][4][5][6][7][8].…”

“…In particular, the injury risk might be unacceptable when processing the tissues near the nerve and blood vessel. Subsequently, femtosecond laser processing of hard tissues is proposed to obtain higher precision and lower thermal damage [3][4][5][6][7][8]。 Nevertheless, how to precisely control laser processing to obtain sufficient stability and safety remains to be further studied. One possible solution is the precise positioning and real-time feedback control.…”