Preliminary study on implantable inductive‐type sensor for continuous monitoring of intraocular pressure

Kim, Young Kook; Kim, Mi Jeung; Park, Ki Ho; Jeoung, Jin Wook; Kim, Seok Hwan; Jang, Cheol In; Lee, Soo Hyun; Kim, Jae‐Hun; Lee, Seok; Kang, Ji Yoon

doi:10.1111/ceo.12573

Cited by 12 publications

(9 citation statements)

References 26 publications

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“…In vitro studies have demonstrated that the Implandata EyeMate is biocompatible with good subjective tolerance in rabbit eyes for up to 25 months. This was confirmed by the lack of intraocular toxicity on histopathology [55, 56]. …”

Section: Permanent Continuous Monitoring Devicesmentioning

confidence: 84%

Systematic Review of Current Devices for 24-h Intraocular Pressure Monitoring

et al. 2016

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Glaucoma is a common optic neuropathy that can lead to irreversible vision loss, and intraocular pressure (IOP) is the only known modifiable risk factor. The primary method of treating glaucoma involves lowering IOP using medications, laser and/or invasive surgery. Currently, we rely on in-office measurements of IOP to assess diurnal variation and to define successful management of disease. These measurements only convey a fraction of a patient’s circadian IOP pattern and may frequently miss peak IOP levels. There is an unmet need for a reliable and accurate device for 24-h IOP monitoring. The 24-h IOP monitoring devices that are currently available and in development fall into three main categories: self-monitoring, temporary continuous monitoring, and permanent continuous monitoring. This article is a systematic review of current and future technologies for measuring IOP over a 24-h period.

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Section: Permanent Continuous Monitoring Devicesmentioning

confidence: 84%

Systematic Review of Current Devices for 24-h Intraocular Pressure Monitoring

et al. 2016

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“…An implantable inductive‐type IOP sensor has wireless pressure‐sensing ability and favourable biocompatibility in the rabbit eye . A telemetric IOP sensor has been implanted in the ciliary sulcus of six patients after cataract surgery and implantation of an intracapsular lens .…”

Section: Potential Limitations For Triggerfish Contact Lens Sensor Momentioning

confidence: 99%

“…A telemetric IOP sensor has been implanted in the ciliary sulcus of six patients after cataract surgery and implantation of an intracapsular lens . Further development of both of these methods may result in the capacity to continuously monitor IOP …”

Section: Potential Limitations For Triggerfish Contact Lens Sensor Momentioning

confidence: 99%

“…These constraints indicate the potential for the loss of what might be useful data about fluctuations of IOP. Given the potential importance of short and long‐term IOP fluctuation in the diagnosis and treatment of glaucoma, a reliable method of continuous monitoring is highly desirable . Any method for continuous IOP monitoring should be safe and biocompatible, provide accurate, reproducible measurements over prolonged periods, function independently of ocular health and/or corneal properties and be directly correlated with currently validated tonometers …”

Section: Potential Importance Of Continuous Iop Monitoringmentioning

confidence: 99%

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The importance of and potential for continuous monitoring of intraocular pressure

McMonnies

2017

Clinical and Experimental Optometry

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Monitoring intraocular pressure (IOP) is a critically important part of glaucoma management; however, clinical tonometry predominantly involves sitting postures and is unable to detect variations in response to posture changes, muscular effort, deep respirations and during a wide range of activities, such as playing high wind-resistance instruments and wearing swimming goggles in addition to eye touching and rubbing. For example, the usefulness of 24-hour tonometric phasing may be increased, if nocturnal assessments included side and prone sleeping postures rather than being limited to supine posture tonometry. Continuous monitoring of IOP, which allows unrestricted involvement in a full range of sleep and non-sleep IOP elevating activities would provide an ideal method of quantifying the frequency, duration and degree of episodes of elevation in addition to physiological and pathological circadian rhythmic variations due to treatment. Apart from the degree of exposure to episodes of elevation of IOP, genetic influences and family history of glaucoma, other factors which are or could be associated with increased susceptibility to develop or progress glaucomatous pathology include age, frailty, race, type and degree of refractive error, systemic hypotension and hypertension, vasospasm, migraine, pigmentary dispersion syndrome, pseudoexfoliation syndrome, obstructive sleep apnoea syndrome, diabetes as well as medication interactions and side effects. Such information, when combined with all details relating to episodes of elevation of IOP, appears likely to be a strong basis for the detection, diagnosis and treatment of glaucoma. This review examines the limitations of methods of longitudinal monitoring of IOP with reference to their validity and the varying degrees of invasiveness involved. Also mentioned is the potential value of knowing the frequency, duration and level of variations of optic nerve subarachnoid space pressure, as the interaction of such changes with IOP and their potential influence on the lamina cribrosa, may help determine pathological significance.

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“…This device can only measure relative changes rather than determine absolute pressure. 31 There are currently many new intraocular sensor devices in development [32][33][34] and if any of these are proven to be accurate and safe, reliable continuous IOP monitoring for many patients may soon become a reality.…”

Section: Q: What Future Developments Can We Look Forward To In 2018?mentioning

confidence: 99%

Recent Developments in Glaucoma

Lim¹

2017

European Ophthalmic Review

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Glaucoma continues to exert a heavy disability and economic burden and is the most frequent cause of irreversible blindness worldwide. In 2015, 57.5 million people globally were affected by open-angle glaucoma and this is predicted to increase to 65.5 million by 2020. The prevalence of glaucoma increases with age in all populations and generally more men and people of Hispanic and Black race are affected. Effective treatments to lower and maintain intraocular pressure (IOP) and convenient means of continuously monitoring it remain substantial unmet medical needs. In this expert interview Kin Sheng Lim from Guy’s and St Thomas’ Hospitals, London, UK, discusses the new developments to improve this situation and are therefore of great interest to ophthalmologists and to the wider population who are at risk from glaucoma.

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Preliminary study on implantable inductive‐type sensor for continuous monitoring of intraocular pressure

Abstract: The implantable inductive-type IOP sensor demonstrated wireless pressure-sensing ability and favourable biocompatibility in the rabbit eye.

Cited by 12 publications

References 26 publications

Systematic Review of Current Devices for 24-h Intraocular Pressure Monitoring

Systematic Review of Current Devices for 24-h Intraocular Pressure Monitoring

The importance of and potential for continuous monitoring of intraocular pressure

Recent Developments in Glaucoma

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