Preliminary study on chitosan modified glass ionomer restoratives

Petri, Denise Freitas Siqueira; Donegá, Juliana; Benassi, André M.; Bocangel, Jorge A.J.S.

doi:10.1016/j.dental.2006.06.038

Cited by 79 publications

(73 citation statements)

References 19 publications

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“…[10][11][12] Chitin is chemically a polymeric N-acetyl-D-glucosamine and is mainly contained in the shells of crabs and shrimps. 13 Particular properties of chitosan are especially important. It has a pH of 6.3, which is suitable to buffer the oral pH value high enough to prevent the deleterious action of organic acids on the tooth surface.…”

Section: Introductionmentioning

confidence: 99%

Does a chitosan-containing dentifrice prevent demineralization around orthodontic brackets?

Uysal¹,

Amasyalı²,

Özcan³

et al. 2011

The Angle Orthodontist

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Objective: To test the null hypothesis that there is no significant difference between the chitosancontaining and conventional nonfluoridated dentifrices in inhibition of enamel demineralization around orthodontic brackets. Materials and Methods: Sixteen orthodontic patients who were scheduled to have extraction of four first premolars for orthodontic reasons were divided into two groups after the power of the study was estimated. Patients in the experimental group were instructed to use chitosan-containing dentifrice (AloeDent), and patients in the control group were instructed to use nonfluoridated dentifrice (Sensodyne Mint). After 60 days, the teeth were extracted and longitudinally sectioned. The demineralization was assessed by cross-sectional microhardness. The determinations were made at the bracket edge cementing limits and at occlusal and cervical points, 100 mm and 200 mm away from the edge. In all these positions, indentations were made at depths of 10, 20, 30, 50, 70, and 90 mm from the enamel surface. Analysis of variance (ANOVA) and Tukey test were used for statistical evaluation at P , .05 level. Results: ANOVA showed statistically significant differences for the factors of dentifrice type, position, and depth (P 5 .000). Statistically significant differences for microhardness values between two tested dentifrices were observed up to 20 mm of depth from the enamel surface (P , .05). Lower microhardness values were found for nonfluoridated dentifrice. Significant microhardness differences were also determined between materials at occlusal and cervical 0 mm positions (P , .05). At these positions, chitosan-containing dentifrice showed lower demineralization than the control. Conclusion: Chitosan-containing dentifrice may reduce the enamel decalcification found in patients with poor oral hygiene. The null hypothesis is rejected. (Angle Orthod. 2011;81:319-325.)

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Section: Introductionmentioning

confidence: 99%

Does a chitosan-containing dentifrice prevent demineralization around orthodontic brackets?

Uysal¹,

Amasyalı²,

Özcan³

et al. 2011

The Angle Orthodontist

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“…These properties may be responsible for Fuji IX exhibiting a good marginal seal. In 2007, Petri et al 21 observed the improved mechanical properties of GIC, on adding small amounts of chitosan into GIC. It was suggested that if the interfacial tension between each component is high, or in other words, the adhesion between each component is weak, the mechanical properties are poor.…”

Section: Microleakage and Bio-active Gicmentioning

confidence: 99%

Bio Chitosan/Nanodiamond GIC from Design to Applications: In Vitro Investigation

Perchyonok¹

2017

ATROA

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Background: Restoring the carious lesion at an early stage is an ideal treatment option in order to preserve the primary teeth until its normal anticipated exfoliation. This helps to assist in the maintenance of a healthy oral environment and arch length as well as to preserve the function of mastication and speech. However, even a simple restorative treatment plan is likely to evoke anxiety in a pediatric patient and may prove to be a challenge to the clinician. Hence when choice of the restorative material is made, simplicity of clinical application of the material should be considered along with other properties of the restorative material. The interest in the clinical use of glass ionomer cements (GIC) arose mainly from their particular advantage of requirement of a short time to fill the cavity which is a desirable property while treating young children. Results:In general there was an increase in bond strength of the dentine treated with the modified GIC materials compared to the bond strength of the conventionally bonded teeth. Functionalized bio-materials showed the highest adhesive force, and this result can be expected because of the well-known intrinsic bio-adhesive properties of chitosan [Vasir 2002] All the test samples gave an average inhibition zone larger than the tetracycline control disc, thereby confirming the antibacterial activity of the different bio-active GIC's containing combinations against Stapylococcus aureus. Using the Student's T-test (p<0.01), there was a significant difference between the rest of the samples when compared to each other and the positive control. Based on the scores that were tabulated, the p-value was >0.05, thus indicative that there was no significant difference between micro-leakage of glass ionomer cement, chitosan modified glass ionomer cement, nanodiamond modified glass ionomer cement as well as chitosan: nanodiamond modified glass ionomer cements. Conclusion:Incorporation of chitosan or nanodiamond or combination of Chitosan/ nanodiamond into the conventional GIC provides a promising multi-dimensional functional biomaterial with excellent properties such as increased shear bond strength, certain degree of microbiological properties, good bio-adhesion without compromising important properties such as microleakage. Clinical significance:The interest in the clinical use of glass ionomer cements (GIC) arose mainly from their particular advantage of requirement of a short time to fill the cavity which is a desirable property while treating young children. The additional benefits of the application of bioactive GIC sealant materials lies in the build-in functionality of these materials to chemical attack in oral cavity as well as additional antibacterial action. Advances in Tissue Engineering and Regenerative MedicineResearch Article Open Access However, addition of any agent into a material in an attempt to improve the properties, should not jeopardize any other desirable property of the parent material. An important property responsible for the success o...

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“…6 Pawlowska cit. Petri et al, 7 mengatakan bahwa bahan primer yang telah ditambahkan dengan kitosan dan diaplikasikan pada pulpa gigi tikus dapat menyebabkan sedikit perubahan patologis reversibel.…”

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Evaluasi karakteristik abu sekam padi dengan kitosan molekul tinggi nanopartikel sebagai bahan dentinogenesis (Characteristic evaluation of rice husk ash with chitosan high molecule nanoparticle as dentinogenesis material)

Silalahi

Abidin

Agusnar

2014

Dent. J. (Majalah Kedokteran Gigi)

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Preliminary study on chitosan modified glass ionomer restoratives

Cited by 79 publications

References 19 publications

Does a chitosan-containing dentifrice prevent demineralization around orthodontic brackets?

Does a chitosan-containing dentifrice prevent demineralization around orthodontic brackets?

Bio Chitosan/Nanodiamond GIC from Design to Applications: In Vitro Investigation

Evaluasi karakteristik abu sekam padi dengan kitosan molekul tinggi nanopartikel sebagai bahan dentinogenesis (Characteristic evaluation of rice husk ash with chitosan high molecule nanoparticle as dentinogenesis material)

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