Preliminary study of the significance of reverberation by IVUS detection for patients with severe calcified lesions

You, Wei; Zhang, Hongli; Xu, Tian; Meng, Pin; Zhou, Yu-He; Wu, Xiangqi; Wu, Zhiming; Tao, Bilin; Guo, Ya-Jie; Nong, Jia-Cong; Ye, Fei

doi:10.1007/s10554-022-02537-8

Cited by 2 publications

(2 citation statements)

References 17 publications

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“…(G1-2) have shown that atherosclerosis was dominant and more manifested by intimal calcification [46,47], in which most of these studies used computerized tomography images for analysis [41,42,44], and a few of them used intracoronary imaging such as OCT [43,48,49]. Our study found that patients with mild CKD may have calcification growth in both intima and media of coronary arteries, which may be related to the involvement of multiple factors [35].…”

Section: Plos Onementioning

confidence: 83%

“…Our study found that patients with mild CKD may have calcification growth in both intima and media of coronary arteries, which may be related to the involvement of multiple factors [35]. Currently, in vivo studies, even with the use of more advanced intravascular imaging technology, there is still no clear quantitative method to analyze intimal and media calcification [48,49], and it is more difficult to study the natural outcome of plaque morphology. In our study, we used a novel method to analyze the changes in calcified morphology by OFR software, which measured ΔMaxCT (indicating the thickness changes of calcification) and ΔC-to-M (indicating the direction of calcification changes).…”

Section: Plos Onementioning

confidence: 99%

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Dynamic natural components and morphological changes in nonculprit subclinical atherosclerosis in patients with acute coronary syndrome and mild chronic kidney disease at the 1-year follow-up and clinical significance at the 5-year follow-up

Nong,

You,

Wang

et al. 2024

PLoS ONE

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Introduction The natural outcome of coronary plaque in acute coronary syndrome (ACS) patients with chronic kidney disease (CKD) is unique, which can be analyzed quantitatively by optical flow ratio (OFR) software. Methods A total of 184 ACS patients with at least one nonculprit subclinical atherosclerosis (NSA) detected by optical coherence tomography (OCT) at baseline and 1-year follow-up were divided into non-CKD group (n = 106, estimated glomerular filtration rate (eGFR)> 90 mL/(min×1.73 m2)) and mild CKD group (n = 78, 60≤eGFR<90 mL/(min×1.73 m2)). Changes of normalized total atheroma volume (TAVn) of NSA was the primary endpoint at the 1-year follow-up. Results Patients with mild CKD showed more TAVn progression of NSA than non-CKD (p = 0.019) from baseline to the 1-year follow-up, which was mainly due to an increase in calcium TAVn (p<0.001). The morphological change in the maximal calcification thickness (p = 0.026) was higher and the change in the distance from the calcified surface to the contralateral coronary media membrane (ΔC-to-M) at the maximal cross-sectional calcium area was lower (p<0.001) in mild CKD group than in non-CKD group. Mild CKD had more NSA related MACEs at the 5-year follow-up than non-CKD (30.8% vs. 5.8%, p = 0.045). Conclusions Mild CKD patients had more plaque progression of NSA which showed the increase of calcium component with more protrusion into the lumen morphologically at the 1-year follow-up and a higher corresponding incidence of NSA-related MACEs at the 5-year follow-up. Trial registration Clinical Trial registration ClinicalTrials.gov. NCT02140801. https://classic.clinicaltrials.gov/ct2/show/NCT02140801.

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Section: Plos Onementioning

confidence: 83%

Section: Plos Onementioning

confidence: 99%

Dynamic natural components and morphological changes in nonculprit subclinical atherosclerosis in patients with acute coronary syndrome and mild chronic kidney disease at the 1-year follow-up and clinical significance at the 5-year follow-up

Nong,

You,

Wang

et al. 2024

PLoS ONE

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Contemporary approach to heavily calcified lesions: tools of the trade, challenges, and pitfalls

Russo,

Massaro,

Benedetto

et al. 2024

Vessel Plus

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Coronary artery calcifications (CAC) affect more than 90% of men and more than 67% of women older than 70; the spread is mainly due to the high occurrence of major cardiovascular risk factors. The presence of CAC can be detected by several noninvasive and invasive methods like computed tomography (CT), coronary angiography (CA), Intravascular Ultrasound (IVUS), and Optical Coherence Tomography (OCT), with each system providing different information that can be used in the treatment strategy of CAC. Several devices can modify calcium during PCI: high-pressure non-compliant balloons, cutting/scoring balloons, atheroablative technologies, and intravascular Lithotripsy (IVL). Each technique has advantages and disadvantages that every interventional cardiologist should know to perform an optimal PCI and to achieve the best result and clinical outcome. This is a narrative review that aims to illustrate the contemporary management of CAC, focusing on the available techniques to assess calcifications and their novel advancements and explaining the existing tools to treat CAC with a focus on their significant challenges and pitfalls.

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Preliminary study of the significance of reverberation by IVUS detection for patients with severe calcified lesions

Cited by 2 publications

References 17 publications

Dynamic natural components and morphological changes in nonculprit subclinical atherosclerosis in patients with acute coronary syndrome and mild chronic kidney disease at the 1-year follow-up and clinical significance at the 5-year follow-up

Dynamic natural components and morphological changes in nonculprit subclinical atherosclerosis in patients with acute coronary syndrome and mild chronic kidney disease at the 1-year follow-up and clinical significance at the 5-year follow-up

Contemporary approach to heavily calcified lesions: tools of the trade, challenges, and pitfalls

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