Preliminary Study of the Effects of some Herbal Drugs on the Heamatological and Biochemical Parameter of Winster Albino Rats

Akintelu, Sunday Adewale; Abiola, babawale Emmanuel,; Oluwakayode, Ajayi Samuel; Olabemiwo, Ojeyemi Matthew,

doi:10.18483/ijsci.2032

Cited by 3 publications

(1 citation statement)

References 3 publications

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“…The susceptibility of the fungi strains to synthesized AgNPs was in the order of Candida tropicalis > Aspergillus flaws > Fusarium oxysperium > Candida albican. The antifungal activity of this study was found to be higher than that obtained from the previous studies [46][47][48][49][50][51]. The higher antifungal potency…”

Section: Antifungal Activity Of Synthesized Agnpscontrasting

confidence: 79%

Green Synthesis, Characterization, and Antifungal Activity of Synthesized Silver Nanoparticles (AgNPS) from Garcinia Kola Pulp Extract

2021

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The prevention or cure of microbial infections are mostly combated with the use of antibiotics. However, the activity of most of the available antibiotics had been nullified by fungi resistance. This study was aimed at the investigation of the antifungal property of silver nanoparticles (AgNPs) synthesized from Garcinia kola pulp. The pulp of Garcinia kola were obtained from its ripe fruit, dried and pulverized into fine particles and extracted with water. The extract was mixed with 1mM aqueous silver nitrate following necessary procedure to form AgNPs. The AgNPs synthesized were characterized and screened against tested fungi using standard method. The inhibition zones were measured and recorded after incubation of the plates at a temperature of 35 °C for 24 h. The morphological assessment of the synthesized AgNPs confirmed the variation in particle size ranging from 24 to 10 nm with an average size distribution of 17 nm and a spherical shape. The synthesized AgNPs show good activity against tested fungi strains with inhibition zones ranging from 6 to 17 mm which is comparable to the inhibition zones demonstrated by the control in the range of 18 to 24 mm. This study indorsed the use of AgNPs against fungi infections owning to the antifungal activity displayed against tested fungi strains. Keywords Silver nanoparticles • Garcinia kola pulp • Clinical isolates and fungi activity

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Section: Antifungal Activity Of Synthesized Agnpscontrasting

confidence: 79%

Green Synthesis, Characterization, and Antifungal Activity of Synthesized Silver Nanoparticles (AgNPS) from Garcinia Kola Pulp Extract

2021

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Evaluation the role of vitamin B12 and pomegranate pulp extract in rats with phenyl hydrazine-induced anemia

Alwan,

Raddam

2023

PHYSICAL MESOMECHANICS OF CONDENSED MATTER: Physical Principles of Multiscale Structure Formation and the Mechanisms of Nonline

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Characterization and Pharmacological Efficacy of Silver Nanoparticles Biosynthesized Using the Bark Extract of Garcinia Kola

Akintelu

Olugbeko

Folorunso

et al. 2020

Journal of Chemistry

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The delinquent peril of bacterial infections affecting human kind is becoming unbearable. This study was embarked on to investigate the antimicrobial activity of biosynthesized silver nanoparticles (AgNPs) using Garcinia kola bark extract against some bacteria strains. Fresh barks of Garcinia kola were obtained from the “Gbeleju” farm land in Irele town in Ondo state region of Nigeria. Exactly 0.4 g of previously pulverized bark of Garcinia kola was immersed into 20 mL of distilled water and heated at 60–70°C for 10 minutes yielding the extract. The biosynthesized nanoparticle was characterized with UV spectroscope, Fourier infrared spectroscope (FTIR), transmission electron microscope (TEM), and energy dispersive X-Ray analyzer (EDX). Then, 0.2 g of the silver nanoparticles was dissolved in 2 ml of water to yield 100 mg/ml of the stock solution which was further diluted for the antibacterial analysis via the disc diffusion method. The result obtained from the analytical characterization of the biosynthesized silver nanoparticles revealed a spherical particle shape, particle size in the range of 12.23 to 27.90 nm with an average size of 20.07 nm via TEM analysis. The FTIR analysis confirmed the presence of -OH functional group for the stabilization of the silver nanoparticles formed due to the broad peak at wavelength 3324.52 and 3344.21 cm−1. The EDX analysis revealed carbon, nitrogen, oxygen, aluminum, potassium, copper, and silver as the elements present in the nanoparticles. Results obtained from the antibacterial screening of the biosynthesized AgNPs showed inhibitory potential that are capable of obstructing the growth of the test bacteria. This investigation ascertained the biosynthesized AgNPs as a remedy for curing bacterial infections and also a promising source for novel antibacterial agent.

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Preliminary Study of the Effects of some Herbal Drugs on the Heamatological and Biochemical Parameter of Winster Albino Rats

Cited by 3 publications

References 3 publications

Green Synthesis, Characterization, and Antifungal Activity of Synthesized Silver Nanoparticles (AgNPS) from Garcinia Kola Pulp Extract

Green Synthesis, Characterization, and Antifungal Activity of Synthesized Silver Nanoparticles (AgNPS) from Garcinia Kola Pulp Extract

Evaluation the role of vitamin B12 and pomegranate pulp extract in rats with phenyl hydrazine-induced anemia

Characterization and Pharmacological Efficacy of Silver Nanoparticles Biosynthesized Using the Bark Extract of Garcinia Kola

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