Preliminary Study: Environmental Assessment of Perchloroethylene in Dry-Cleaning Facilities in the UAE

Habib, Sedra; Ahmed, Hafsa; Al-Muhairi, Naema; Ziad, Reem

doi:10.1155/2018/1732906

Cited by 7 publications

(10 citation statements)

References 7 publications

(8 reference statements)

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“…Direct skin contact with liquid PERC may lead to erythema, papules and burns (19) . Furthermore, the findings of other study also demonstrated that the dry-cleaning workers exposed to PERC are at risk of developing acute or chronic adverse health effects, depending on the concentrations of PERC (13) . Other principle finding of the present study was a non-significant alteration in the hematological parameters in PERC-exposed dry cleaning workers compare with the non-exposed group.…”

Section: Discussionmentioning

confidence: 77%

“…A preliminary study conducted by Habib et al (2018) has concluded that PERC is a widelyspread cleaning solvent, and the exposure of PERC among dry-cleaning workers is high. Therefore, installation of local exhaust ventilation systems and monitoring devices of PERC level is very important among dry-cleaning along with increase the awareness of workers about the harmful effects of PERC and the significance of using personal protective equipment (PPE) while performing their job such as wearing appropriate chemical resistant gloves and clothing, safety goggles with a face shield for eye protection and respirator for respiratory protection (13) . In some countries, manufacturers have begun using alternative cleaning methods that do not require the use of PERC (14) .…”

Section: Introductionmentioning

confidence: 99%

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Health Hazards, Hematological and Biochemical Alterations in Dry-Cleaning Workers using Perchloroethylene.

Marouf¹

2022

IJPS

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Perchloroethylene (PERC) is commonly used as a dry-cleaning solvent, it is attributed to many deleterious effects in the biological system. The study aimed to investigate the harmful effect associated with PERC exposure among dry-cleaning workers. The study was carried out on 58 adults in two groups. PERC-exposed group; include thirty-two male dry-cleaning workers using PERC as a dry-cleaning solvent and twenty-six healthy non-exposed subjects. History of PERC exposure, use of personal protection equipment (PPE), safety measurement of the exposed group was recorded. Blood sample was taken from each participant for measurement of hematological markers, liver and kidney function tests. The results showed that 28.1% of the workers were using PPE regularly while 71.9% of the workers were not. Most of the workers 31(96.9%) were disposed of their waste products in improper way. Non-significant differences were observed in hematological indices between PERC-exposed group and non-exposed group. Serum level of kidney and liver function markers of the dry-cleaning workers were higher with statistically significant difference compared with the non-exposed group. In conclusion, a non-significant alteration in hematological parameters, while significant changes in part of liver and kidney functions indices have been demonstrated. Clinical observation indicated a harmful effect in PERC-exposed group. Key words: Occupational, PERC, personal protective equipment, dry cleaner

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Section: Discussionmentioning

confidence: 77%

Section: Introductionmentioning

confidence: 99%

Health Hazards, Hematological and Biochemical Alterations in Dry-Cleaning Workers using Perchloroethylene.

Marouf¹

2022

IJPS

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“…The development of a safety culture among dry cleaners focusing on proper solvent handling and workplace sanitation can also help to prevent potential toxic effects from tetrachloroethylene exposure. Fifth, the use of PPE like mask and hand gloves should be used correctly (Manuele, 2005;Lucas et al, 2015;Azimi et al, 2017;Habib et al, 2018).…”

Section: Discussionmentioning

confidence: 99%

Literature Review: Biological Monitoring of Occupational Tetrachloroethylene Exposure in Workers

Amalia

Ilyas

2021

IJOSH

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Introduction: One of the most common chlorinated solvents in the world is tetrachloroethylene (TCE) because it is widely used in various industries. Exposure to tetrachloroethylene can cause health problems so biological monitoring is necessary to do. The aim of this research is to assess which one is more feasible to use among the various types of biological monitoring for tetrachloroethylene exposure, based on the evidence-based literature. Methods: The literature searching was performed via electronic databases from PubMed, Scopus, and Proquest. The keywords used were “biological monitoring”, “biomonitoring”, “tetrachloroethylene”, “perchloroethylene”, “work” and “occupation”. The articles were chosen based on the given inclusion and exclusion criteria. Selected articles were then critically appraised. Results: Initially 29 papers were collected, but only6 cross-sectional articles were selected after the screening process and manual searching. Based on the selected evidence-based literatures, statistically meaningful associations were found between tetrachloroethylene exposure and tetrachloroethylene in blood in pre- and end-of-shift, in urine at end of shift, and in exhaled air at end-of-shift. Moreover, micronucleus frequency and DNA damages between dry cleaning workers and the controls differed significantly. Conclusion: The level of tetrachloroethylene in blood, urine, and exhaled air becomes an appropriate biological exposure index for assessing tetrachloroethylene exposure in dry-cleaning workers. In Indonesia, biomonitoring that is more feasible to be implemented is micronucleus frequency evaluation from buccal mucosal epithelial smears since it is a simpler, faster, and less expensive procedure.Keywords: biological monitoring, biomonitoring, occupational exposure, tetrachloroethylene

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“…This compound is a halogenated aliphatic hydrocarbon. [ 1–3 ] PEC is a solvent that is widely used in the dry cleaning industry. [ 4–6 ] Occupational exposure to it occurs via inhalation and skin contact in the workplace.…”

Section: Introductionmentioning

confidence: 99%

“…Research has shown that exposure to PEC in the workplace is associated with toxic effects on vital organs including the brain, lungs, liver, and kidneys. [3,10,11] According to The National Institute for Occupational Safety and Health (NIOSH), PEC is recognized as an occupational carcinogen and the International Agency for Research on Cancer (IARC) classifies it as a carcinogen in Group 2A. [7,12] Reports from the Occupational Safety and Health Administration (OSHA) show that exposure to levels above 100 ppm of PEC can be associated with damage to the brain system in humans.…”

mentioning

confidence: 99%

The perchloroethylene‐induced toxicity in dry cleaning workers lymphocytes through induction of oxidative stress

Ghahri

Dehghan

Seydi

et al. 2022

J Biochem & Molecular Tox

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Evaluation of the compounds and metabolites, and studying their side effects in the workplace is essential. This study was designed to evaluate the exposure of dry cleaning workers to perchloroethylene (PEC), and its liver and kidney damage, and oxidative stress in B-lymphocytes isolated from the workers. Blood samples were evaluated for liver (alanine transaminase [ALT] and aspartate transaminase [AST]) and kidney (BUN and creatinine) markers. For measurement of PEC, exhaled, personal, and ambient air samples were collected and analyzed gas chromatography (GC-FID) through the NIOSH 1003 and 3704 methods. Also, the parameters of oxidative stress including the level of reactive oxygen species (ROS), glutathione (GSH), oxidized glutathione (GSSG), and lipid peroxidation (LPO) in B-lymphocytes were evaluated. The results showed that the levels of liver enzymes ALT and AST in dry cleaning workers are higher than in the control group. The personal exposure levels and exhaled air concentration of PEC in dry cleaning workers were above the recommended national occupational exposure limits (OELs) and the biological exposure index (BEI). The levels of ROS, LPO, and GSSG in B-lymphocytes from the dry cleaning workers are higher than the control group, and the levels of GSH in dry cleaning workers are lower. The results suggested that exposure of dry cleaning workers to PEC could be associated with liver damage and oxidative damage in B-lymphocytes.

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Preliminary Study: Environmental Assessment of Perchloroethylene in Dry-Cleaning Facilities in the UAE

Cited by 7 publications

References 7 publications

Health Hazards, Hematological and Biochemical Alterations in Dry-Cleaning Workers using Perchloroethylene.

Health Hazards, Hematological and Biochemical Alterations in Dry-Cleaning Workers using Perchloroethylene.

Literature Review: Biological Monitoring of Occupational Tetrachloroethylene Exposure in Workers

The perchloroethylene‐induced toxicity in dry cleaning workers lymphocytes through induction of oxidative stress

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