Preliminary studies on the effects of Amaranthus spinosus Leaf Extract as an Anthelmintic in growing pigs

Assiak, IE; Olufemi, Benjamin E.; Ayonde, G.O.; Onigemo, M.A

doi:10.4314/tv.v20i2.4521

Cited by 10 publications

(7 citation statements)

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“…It is reported for its anti-inflammatory properties (Olumayokun et al, 2004), the effect on hematology (Olufemi et al, 2003), and immunemodulatory activity had been reported (Tatiya et al, 2007). It has anti-androgenic activity (Murgan et al, 1993a), anthelmintic properties (Assiak et al, 2002) and effect on biochemical changes in epididymis (Murgan et al, 1993b). The drawback is that the plant has spines that can cause injury to the mouths of grazing animals and few cases of poisoning in cattle have been reported; it induces abortion and may cause renal failure.…”

Section: A Cruentusmentioning

confidence: 99%

Nutritional Value and Utilization of Amaranthus (<i>Amaranthus</i> spp.) – A Review

Alegbejo¹

2014

Bayero J. Pure App. Sci.

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Amaranth consists of 60-70 species, 40 of which are considered native to the Americas. They are grown in the temperate and tropical climates, and are used as grain or vegetable. They are highly nutritious, contain vitamins and minerals. The leaves, shoots, tender stems and grains are eaten as pot herb in sauces or soups, cooked with other vegetables, with a main dish or by itself. The plants are used as forage for livestock. Traditionally, the boiled leaves and roots are used as: laxative, diuretic, anti-diabetic, antipyretic, anti-snake venom, antileprotic, anti-gonorrheal, expectorant, to relieve breathing in acute bronchitis. It also has anti-inflammatory properties, immunomodulatory activity, anti-androgenic activity and anthelmintic properties.

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Section: A Cruentusmentioning

confidence: 99%

Nutritional Value and Utilization of Amaranthus (<i>Amaranthus</i> spp.) – A Review

Alegbejo¹

2014

Bayero J. Pure App. Sci.

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“…The plant extract possesses severe effects in hematology (Olufemi et al 2003). It shows immunomodulatory (Tatiya et al 2007), anthelmintic (Assiak et al 2002), analgesic (Krishnamurthi et al 2010), antidiabetic, antihyperlipidemic, spermatogenic (Girija and Lakshman 2011;Sangameswaran and Jayakar 2008), hepatoprotective (Zeashan et al 2008(Zeashan et al , 2009, anticancer (Cristine et al 2013), antioxidant (Odhavo et al 2007;Zeashan et al 2009) and chemoprotective activities . A. spinosus contains several active constituents like alkaloids, flavonoids, glycosides, phenolic acids, steroids, terpenoids, saponins, betalains, b-sitosterol, stigmasterol, rutin, catechuic tannins, etc.…”

Section: Introductionmentioning

confidence: 99%

Cytotoxic and apoptotic activities of extract of Amaranthus spinosus L. in Allium cepa and human erythrocytes

Prajitha

Thoppil

2016

Cytotechnology

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The present study examined the apoptosis inducing effects of Amaranthus spinosus L. aqueous extract in Allium cepa root meristematic cells and human erythrocytes. Cytogenetic assay revealed many apoptosis inducing cytogenetic aberrations viz., cytoplasmic breakage, cytoplasmic disintegration, cytoplasmic shrinkage, receding of cytoplasm, cytoplasmic vacuolation, enucleated cell, ghost cell, nuclear vacuolation, nuclear fragmentation and nuclear disintegration. A remarkable modification of red blood cell surface morphology was observed in the result of RBC assay. The treated RBCs show membrane blebbing and shrinkage, features typical for apoptosis in nucleated cells. Significant induction of cell death was observed in treated Allium root tip cells after Evans blue staining, disclosing the membrane damage potential of the plant extract. TTC assay results in reduced mitochondrial/ metabolic activity in Allium root tip cells after treatment, designating the adverse effect of plant extract on mitochondrial respiratory chain. These results confirm the apoptosis inducing potential of A. spinosus extract. Confirming the present results by further in vitro studies, it can be effectively targeted against cell proliferation during cancer treatment by inducing apoptosis. Thus from the present investigation it can be concluded that the aqueous extract of A. spinosus exhibited apoptosis induction and cytotoxic activities.

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“…Genetic and environmental factors, such as UV light exposure and harvesting method, also play an important role in chemical composition. 2 In addition, the genus Amaranthus has been reported to be a lectin-rich genus among the family Amaranthaceae. 3 These lectins extracts have been found to be non-specific, that is, they agglutinate a variety of human and animal erythrocytes including rabbit, rat, guinea-pig, sheep, goat and chicken.…”

Section: Introduction:-mentioning

confidence: 99%

Preliminary Analysis of the Hemagglutinating Activity of Seed Extracts of the Amaranth Genus.

Dandeu¹

2018

IJAR

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In this study, seed extracts of cultivated Amaranthus species were tested for haemagglutinating activity. The extracts were prepared from the seeds of 7 Amaranthus cultivars and analyzed against samples from human, rat and dog erythrocytes. To detect haemoagglutination, 5% suspensions of human blood samples of the types A, B and O were prepared. The presence of polyphenols and saponins were determined in the extracts, yielding positive results for polyphenolics compounds. In order to characterize the proteins present in the amaranth extracts, the protein gel electrophoresis technique was applied. All extracts analyzed showed protein activity, and similar protein profile. The extracts reacted strongly with red blood cells (RBCs) from human ABO blood groups. It also reacted with rat and dog RBCs. The hemagglutinating activity was exhibited by the all extracts and the precipitated lectins from all species tested, however, hemolytic activity was not observed. The results obtained from the Amaranthus extracts indicate that it is non-specific for glycosylated antigens of the ABO system. The findings provide essential information for their use as potential hemoclasification reagents in the immunohematology laboratory.

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Preliminary studies on the effects of Amaranthus spinosus Leaf Extract as an Anthelmintic in growing pigs

Cited by 10 publications

References 0 publications

Nutritional Value and Utilization of Amaranthus (<i>Amaranthus</i> spp.) – A Review

Nutritional Value and Utilization of Amaranthus (<i>Amaranthus</i> spp.) – A Review

Cytotoxic and apoptotic activities of extract of Amaranthus spinosus L. in Allium cepa and human erythrocytes

Preliminary Analysis of the Hemagglutinating Activity of Seed Extracts of the Amaranth Genus.

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