Preliminary Screening of Phytochemical Constituents, Antioxidant and Antimicrobicidal Activities in the Methanolic Leaf Extract of Couroupita Guianensis

Ilangovan, Sujatha; Thavasumani, P

doi:10.22159/ajpcr.2021.v14i1.39923

Cited by 2 publications

(1 citation statement)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Kandungan kimia yang terdapat pada daun sirih adalah flavonoid, saponin, polifenol, dan minyak astari. Kandungan kimia ini ada yang bekerja sebagai antimikroba yaitu saponin dan antioksidan yaitu flavonoid (Ilangovan dan Thavasumani et al 2021). Menurut Febia et al (2020), kandungan minyak atsiri pada daun sirih berfungsi sebagai fungisida nabati dan antijamur.…”

Section: Pendahuluanunclassified

Kadar Kolesterol, Asam Urat dan Glukosa Darah Ayam Petelur yang Diberi Jus Daun Sirih (Piper betle Linn) pada Level yang Berbeda

Badaruddin

Aka

Ollong

et al. 2021

J. Ilmu Peternak. dan Vet. Trop. (Journal Trop. Anim. Vet. Sci.

View full text Add to dashboard Cite

This study aims to assess cholesterol, uric acid and blood glucose levels in laying hens which are fed with the addition of betel leaf juice (Piper Bettle Linn). There were 16 chickens used in layer phase hens. The cage used is an individual cage equipped with a place for feeding and drinking water. The treatments in this study consisted of: (P0) commercial feed + 0 ml of betel leaf juice, (P1) commercial feed + 5 ml of betel leaf juice, (P2) commercial feed + 10 ml of betel leaf juice, and (P3) commercial feed + 15 ml of betel leaf juice. The variables observed were cholesterol, uric acid and blood glucose levels. The data obtained from the research results were analyzed using variance and continued with Duncan's multiple range test. The results showed that the administration of betel leaf juice had no significant effect (p <0.05) on cholesterol, uric acid and blood glucose levels in layer phase hens. Based on the results of the study, it can be concluded that the administration of betel leaf juice does not affect the amount of cholesterol, uric acid, and glucose levels in layer phase hens, but these conditions are still in normal physiological conditions. Keywords: uric acid, layer hens, glucose, cholesterol ABSTRAK Penelitian ini bertujuan untuk mengkaji tentang kadar kolesterol, asam urat dan glukosa darah ayam petelur yang diberi penambahan jus daun sirih (Piper betle Linn) pada level yang berbeda. Ayam yang digunakan sebanyak 16 ekor induk ayam petelur betina fase layer. Kandang yang digunakan yaitu kandang individu yang dilengkapi dengan tempat pakan dan air minum. Perlakuan pada penelitian ini terdiri atas: (P0) pakan basal + 0 ml jus daun sirih, (P1) pakan basal + 5 ml jus daun sirih, (P2) pakan basal + 10 ml jus daun sirih, dan (P3) pakan basal + 15 ml jus daun sirih. Variabel yang diamati adalah kadar kolesterol, asam urat, dan glukosa darah. Data yang diperoleh dari hasil penelitian dianalisis menggunakan sidik ragam dan dilanjutkan dengan uji jarak berganda Duncan. Hasil penelitian menunjukkan bahwa pemberian jus daun sirih tidak memberikan pengaruh yang nyata (p<0.05) terhdadap kadar kolesterol, asam urat dan glukosa darah ayam petelur fase layer. Berdasarkan hasil penelitian dapat disimpulkan bahwa pemberian jus daun sirih tidak mempengaruhi jumlah kadar kolestero, asam urat, dan glukosa ayam petelur fase layer, namun kondisi tersebut masih dalam kondisi fisiologis normal. Kata Kunci : asam urat, ayam petelur, glukosa, kolesterol

show abstract

Section: Pendahuluanunclassified

Kadar Kolesterol, Asam Urat dan Glukosa Darah Ayam Petelur yang Diberi Jus Daun Sirih (Piper betle Linn) pada Level yang Berbeda

Badaruddin

Aka

Ollong

et al. 2021

J. Ilmu Peternak. dan Vet. Trop. (Journal Trop. Anim. Vet. Sci.

View full text Add to dashboard Cite

show abstract

Evaluation of Clastogenic Potential of Ethanolic Extract of Leaf of <i>Couroupita guianensis</i> using Micronucleus Test in Mice

Nagane

Desai

Barad

et al. 2021

View full text Add to dashboard Cite

Medicinal plants are being used since ancient times in different tribes in India for numerous medicinal purposes. The essential facets of plant-based medicines, such as safety, quality, and efficiency, must be evaluated. Couroupita guianensis is a medicinally important plant, being used conventionally for curing varieties of medical ailments. From the safety point of view, limited information exists for the C. guianensis plant. Considering the facts mentioned above, this study evaluates the genotoxic potential of ethanolic leaf extract of C. guianensis, through an in vivo micronucleus test , which was conducted on mice (Strain: Hsd: ICR (CD1)). The main study consisted of three groups (5 male mice per group): vehicle control (corn oil), a treatment group (2000 mg/kg body weight), and positive control (Mitomycin-C, 1.0 mg/kg body weight). The methodology followed was the standard in vivo procedure as per the internationally approved OECD TG 474 guidelines with a two-day dosing schedule separated by 24 hours. Dose-volume used was 10 mL/kg body weight. Mice in each group exhibited normal behavior and were found clinically normal after dosing. Toxicity to bone marrow, as well as any statistically significant rise in the percent micronucleated polychromatic erythrocytes (% MNPCE), was not detected in mice that were treated with C. guianensis at 2000 mg/kg body weight when compared with the data of concurrent vehicle control. Statistically, a significant rise in the % MNPCE was obtained in mice treated with Mitomycin-C (1.0 mg/kg body weight), which confirmed the test system's suitability, the procedures, and efficiency of conditions employed in the test. Our study concluded that the plant is not showing any genotoxicity and can be used as a medicine to cure various reported ailments.

show abstract

Preliminary Screening of Phytochemical Constituents, Antioxidant and Antimicrobicidal Activities in the Methanolic Leaf Extract of Couroupita Guianensis

Cited by 2 publications

References 16 publications

Kadar Kolesterol, Asam Urat dan Glukosa Darah Ayam Petelur yang Diberi Jus Daun Sirih (Piper betle Linn) pada Level yang Berbeda

Kadar Kolesterol, Asam Urat dan Glukosa Darah Ayam Petelur yang Diberi Jus Daun Sirih (Piper betle Linn) pada Level yang Berbeda

Evaluation of Clastogenic Potential of Ethanolic Extract of Leaf of <i>Couroupita guianensis</i> using Micronucleus Test in Mice

Contact Info

Product

Resources

About