Preliminary Results with TOFPET

Mullani, Nizar A.; Wong, Wai-Hoi; Hartz, Ross K.; Yerian, K.; Philippe, E. A.; Gaeta, J.M.; Gould, K. Lance

doi:10.1109/tns.1983.4332368

Cited by 11 publications

(2 citation statements)

References 10 publications

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“…The TOF scanners developed in the early 1980s (Allemand et al 1980, Mullani et al 1983 were used for research and clinical applications, but the SNR gain provided by the TOF measurements of about 500 ps resolution was offset by the low stopping power of the scintillation crystals, BaF 2 and CsF. The spatial resolution and sensitivity offered by those TOF systems could not compete with the ones achieved on BGO scanners.…”

Section: Introductionmentioning

confidence: 99%

Fourier rebinning of time-of-flight PET data

et al. 2005

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This paper explores fast reconstruction strategies for 3D time-of-flight (TOF) positron emission tomography (PET), based on 2D data rebinning. Starting from pre-corrected 3D TOF data, a rebinning algorithm estimates for each transaxial slice the 2D TOF sinogram that would have been acquired by a single-ring scanner. The rebinned sinograms can then be reconstructed using any algorithm for 2D TOF reconstruction. We introduce TOF-FORE, an approximate rebinning algorithm obtained by extending the Fourier rebinning method for non-TOF data. In addition, we identify two partial differential equations that must be satisfied by consistent 3D TOF data, and use them to derive exact rebinning algorithms and to characterize the degree of the approximation in TOF-FORE. Numerical simulations demonstrate that TOF-FORE is more accurate than two different TOF extensions of the single-slice rebinning method, and suggest that TOF-FORE will be a valuable tool for practical TOF PET in the range of axial apertures and time resolutions typical of current scanners.

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Section: Introductionmentioning

confidence: 99%

Fourier rebinning of time-of-flight PET data

et al. 2005

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“…This result is not unexpected considering the model used in determining flow. The assumption made in the previous study is that during the first pass of tracer through the tissue, there is very little egress of tracer (11,12 several minutes are required for each data point (21 Newer positron imaging systems have improved the temporal resolution by incorporating the time-of-flight of the photon pair, which improves the statistical accuracy of acquired counts (23,24). Positron tomography has superior spatial resolution because of coincidence detection of the two photons emitted during positron decay, which limits random counts and allows quantification.…”

Section: Resultsmentioning

confidence: 99%

Kinetics of rubidium-82 after coronary occlusion and reperfusion. Assessment of patency and viability in open-chested dogs.

Goldstein¹

1985

J. Clin. Invest.

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+0.93±1.51 X 10-3 S-', respectively), except that 4 out of 11 nonviable tissue samples had negative kTs. At reperfusion, viable myocardial samples were all positive (+1.26±1.58 X 10-3 s-'), whereas all irreversibly injured tissues had a negative kT, indicating leakage of tracer (-1.50±1.10 X 10-3 s', P < 0.001). This study suggests that Rb-82 time-activity curves can be useful to determine patency of an infarct related artery and potential viability after reperfusion during myocardial infarction.

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Instrumentation in Positron Emission Tomography

Bohigian¹

1988

JAMA

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Preliminary Results with TOFPET

Cited by 11 publications

References 10 publications

Fourier rebinning of time-of-flight PET data

Fourier rebinning of time-of-flight PET data

Kinetics of rubidium-82 after coronary occlusion and reperfusion. Assessment of patency and viability in open-chested dogs.

Instrumentation in Positron Emission Tomography

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