“…There are many works dedicated to object recognition for Content Based Information Retrieval (CBIR) on histological images. Some of them using techniques based on: (i) texture, many works have compared several feature types on healthy and pathological histological images demonstrating a clear improvement of the algorithms performance and classification process (Markkongkeaw et al, 2013;Peyret et al, 2015;Lai et al, 2011); (ii) shape-based features may capture the particular characteristics to recognise cells or some pathologies -tumours or cancer -, some results suggest that these shapes are not accurate diagnostic features but it can be used for specific aims (Kothari et al, 2013;Melnyk, 2015;Sharma et al, 2012); (iii) colour representation may be used for diagnosis diseases and as an sign to recognise cells or tissues. However, the colour of histological images may vary according to the stain, the preparation procedure 2.…”