Preliminary Results in Unresectable Head and Neck Cancer Treated by Radiofrequency and Microwave Ablation: Feasibility, Efficacy, and Safety

Belfiore, Maria Paola; Sciandra, Mariacarmela; Romano, Francesco; Tartaglione, Tommaso; Lucia, Guido De; Volpe, Tullio Della; Buonomo, Carmela; Cappabianca, Salvatore; Rotondò, Antonio; Belfiore, G

doi:10.1016/j.jvir.2015.05.021

Cited by 18 publications

(10 citation statements)

References 25 publications

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“…Clinical trials have shown therapeutic MW ablation has been used over a range of anatomical sites: fibroids [74], lung [75], kidney [76,77], bone [78,79], pancreas [80], chest wall [81], adrenal glands [82], liver [83], spleen [84], head and neck [85], breast [86] and prostate [87]. A number of clinical MW ablation (which was termed "percutaneous microwave coagulation therapy" or PMCT) studies were performed in Japan [88][89][90].…”

Section: Clinical Mw Ablationmentioning

confidence: 99%

Interstitial microwave treatment for cancer: historical basis and current techniques in antenna design and performance

Ryan¹,

Brace

2016

International Journal of Hyperthermia

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The use of microwaves (MW) for thermal cancer treatment began in the late 1970s. At first, hyperthermia was induced by using single antennas applied interstitially. This was followed by arrays of multiple interstitial antennas driven synchronously at 915 or 2450 MHz. This early work focused on hyperthermia as an adjuvant therapy, but more recently has evolved into a thermally ablative monotherapy. Increased power required to thermally ablate tissues required additional developments such as internally cooled antennas. Larger tumours have also been ablated with MW antenna arrays activated synchronously or non-synchronously. Numerical modelling has provided clinical treatment planning guidance and device design insight throughout this history. MW thermal therapy systems, treatment planning, navigation and image guidance continue to evolve to provide better tools and options for clinicians and patients in order to provide targeting optimisation with the goal of improved treatment for the patient and durable cancer eradication. This paper reviews the history and related technological developments, including antenna design, of MW heating for both hyperthermia and ablation.

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Section: Clinical Mw Ablationmentioning

confidence: 99%

Interstitial microwave treatment for cancer: historical basis and current techniques in antenna design and performance

Ryan¹,

Brace

2016

International Journal of Hyperthermia

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“…At present, image-guided thermal ablation of head and neck lesions is principally described in the treatment of benign and malignant thyroid nodules [27][28][29][30], which includes RFA, MWA, LA and High-Intensity Focused Ultrasound (HIFU). Some studies have employed RFA guided by CT or US in primary and recurrent head and neck malignancies and in cervical lymph nodal metastasis (LNMs) [31][32][33][34][35], which had invariably demonstrated that CT or US guided RFA for head and neck malignancies were feasible, efficacious, and safe. In clinical practice, MWA has increasingly shown advantages such as small surgical trauma, high safety, rapid recovery, fewer complications, repeatable operation and protection effects for organs and tissues.…”

Section: Discussionmentioning

confidence: 99%

A preliminary study on ultrasound-guided percutaneous microwave ablation for palliative treatment of advanced head and neck malignancies

Liao

et al. 2021

International Journal of Hyperthermia

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Objective: To evaluate the safety and efficacy of ultrasound (US)-guided percutaneous microwave ablation (UgPMWA) for palliative treatment of advanced head and neck malignancies. Materials and methods: This study includes 18 consecutive patients with advanced head and neck malignancies (n ¼ 24), who have undergone UgPMWA for palliative treatment at our institution from December 2016 to April 2020. The maximum diameter and volume of the tumor were assessed by US, CT or MRI before microwave ablation (MWA), 1, 3 and 6 months after MWA and every 6 months thereafter. The quality of life was clinically assessed by the University of Washington Head and Neck Quality of Life questionnaire (UW-QOl). Results: The success rate of tumor-targeting microwave antenna placement was 100%. No nerve injury and serious complications or death occurred during the perioperative period. The follow-up duration varied from 1 month to 38 months (11.56 ± 10.23 months) among patients. By the last followup before submission, the value of maximum diameter (5.00 ± 2.90 vs 3.28 ± 2.11 cm. p < 0.05) and tumor volume decreased significantly(74.35 ± 46.88 vs 47.45 ± 24.08 cm 3. p < 0.05)respectively after palliative treatment with UgPMWA. UW-QOl of the patients was improved (59.24 ± 11.51 vs 69.84 ± 8.12, p < 0.05). Conclusion: UgPMWA is safe and effective for the palliative treatment of head and neck malignancies. Ultrasonic guidance can indicate an accurate location of the microwave antenna. It can also monitor the ablation area in real-time during the operation to avoid damage to surrounding normal tissues.

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“…Belfiore et al reported one case of cutaneous fistula which resolved with local therapy and one case of palate perforation that required a prosthetic replacement. 27…”

Section: Outcomes and Complicationsmentioning

confidence: 99%

A Technical Guide to Palliative Ablation of Recurrent Cancers in the Deep Spaces of the Suprahyoid Neck

Hui

Lim

Karandikar

et al. 2022

Semin intervent Radiol

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Treatment options for patients with recurrent head and neck cancer, whether locoregional recurrence of previously treated head and neck cancer or secondary primary malignancy, are limited. Percutaneous ablation is a minimally invasive procedure that can be used with palliative intent in the head and neck to achieve symptomatic relief and local tumor control, potentially fulfilling treatment gaps of current standard of care options. Image guidance is key when navigating the deep spaces of the neck with special attention paid to critical structures within the carotid sheath. This review article provides an overview and highlights the important nuances of performing percutaneous ablations in the head and neck. It covers general principles, ablative modalities, image guidance, procedural technique, expected outcomes, and possible complications.

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Preliminary Results in Unresectable Head and Neck Cancer Treated by Radiofrequency and Microwave Ablation: Feasibility, Efficacy, and Safety

Cited by 18 publications

References 25 publications

Interstitial microwave treatment for cancer: historical basis and current techniques in antenna design and performance

Interstitial microwave treatment for cancer: historical basis and current techniques in antenna design and performance

A preliminary study on ultrasound-guided percutaneous microwave ablation for palliative treatment of advanced head and neck malignancies

A Technical Guide to Palliative Ablation of Recurrent Cancers in the Deep Spaces of the Suprahyoid Neck

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