Preliminary results from an EIT breast imaging simulation system

Wang, W; Tang, Meng‐Xing; McCormick, M.; Dong, Xiuzhen

doi:10.1088/0967-3334/22/1/306

Cited by 23 publications

(12 citation statements)

References 11 publications

(11 reference statements)

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“…Three fixed resistors (3 X, 810 X, and 1.22 kX) were used to calibrate the impedance analyzer before the experiment. The 16-electrode measurements were performed using the cerebral EIT monitoring system developed by our group, 31,39 of which working frequency ranges from 1 to 190 kHz, with measuring accuracy standing at ±0.01% and CMRR over 80 dB. In the experiment, opposite driving/adjacent measuring mode was determined for 16-electrode measurements with the driving current of 1250 lA at 50 kHz, which is proved to be safe for the human.…”

Section: Experimental Setupsmentioning

confidence: 99%

“…1,2,6 To date, some research groups have already applied the technique into imaging study of thorax, abdomen, and other clinical trials. 13,14,17,24,39,44 In the aspect of cerebral EIT, the research mainly includes two directions: cerebral function imaging and dynamic monitoring of brain diseases. As to cerebral function imaging, the group directed by Holder systematically conducted a series of experiments to detect acute stroke, epileptic seizures, and visual evoked potentials by EIT method and had obtained some encouraging conclusions.…”

Section: Introductionmentioning

confidence: 99%

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Performance Evaluation of Five Types of Ag/AgCl Bio-Electrodes for Cerebral Electrical Impedance Tomography

Dai

et al. 2011

Ann Biomed Eng

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Electrical impedance tomography (EIT) is an emerging medical imaging technique, which has already been investigated in several clinical applications due to its low-cost, non-invasiveness, non-radioactivity, high temporal resolution, and great sensitivity to impedance changes. One potential use of EIT is to perform long-term continuous imaging monitoring of brain for patients who suffer from severe cerebral diseases. However, this application requires a demanding performance of electrodes because of the characteristics of cerebral EIT measurements. Although Ag/AgCl bio-electrodes are widely used for clinical practices or EIT research at the moment, influences of different types of Ag/AgCl electrodes on cerebral EIT measurements have not been investigated. In this study, five common types of Ag/AgCl bio-electrodes were put into comparison by measuring the forearm and the brain of 10 healthy adult volunteers and evaluating those data in frequency or time domain in terms of contact impedance, uniformity, signal-to-noise ratio, and stability. Results show that Ag/AgCl powder electrode has an overall best performance with as low contact impedance as commercial ECG electrodes (p > 0.05), high SNR (60.3 ± 4.5 dB), better uniformity (coefficient of correlation 0.95 ± 0.03), and greater stability (slope 0.68 ± 0.03). After further improvement in design and instrumentation, Ag/AgCl powder electrode is likely to become the optimal choice for cerebral EIT measurements and provide feasible technical support for further research or application in cerebral EIT.

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Section: Experimental Setupsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Performance Evaluation of Five Types of Ag/AgCl Bio-Electrodes for Cerebral Electrical Impedance Tomography

Dai

et al. 2011

Ann Biomed Eng

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“…Thus, medical imaging by mapping electrical conductivity gives rise to two key applications: monitoring of pulmonary activity (e.g. Metherall, 1998), screening for early cancer detection (Cherpenin et al, 2001;Wang et al, 2001). Other applications of EIT include imaging of human head (Tidswell et al, 2001) and gastrointestinal and esophogeal function (e.g.…”

Section: Geophysical Imaging Methodsmentioning

confidence: 99%

Linking the Geosciences to Emerging Bio-Engineering Technologies

Cygan¹,

Ho²,

Weiss³

2002

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Is application of Geosciences research at Sandia National Laboratories to biological and human health systems beneficial to the lab's biotechnology efforts? This LDRD project was funded to answer that question for three application areas: biochemistry, bioengineering, and human health. The biochemistry section includes modeling for protein folding and improved drug delivery substrates. For those molecular simulations, a hybrid energy forcefield was developed to model the conformation of an oligopeptide within the clay interlayer. Results demonstrate that the nonbonded interactions are especially important in understanding the control of the structure and function of proteins as modified by inorganic substrates, and that the protein structure may be denatured by the clay surface. More sophisticated molecular simulations involving waters of solvation for the protein, hydrated clay interlayers, and different charged distributions in the clay substrates are recommended for future research. The bioengineering section focuses on drug delivery and hazardous chemical absorption through the skin. Percutaneous absorption of chemicals was developed using a probabilistic, multiphase, heterogeneous model of the skin. Penetration routes through the skin included intercellular diffusion through the stratum corneum, diffusion through aqueous-phase sweat ducts, and diffusion through oil-phase hair follicles. Mass fluxes were calculated for varying lengths of time, and sensitivity analyses showed that the aqueous solubility limit, thickness of the stratum corneum, and aqueous molecular diffusion coefficient were important input parameters. Complex flow and transport models used for enhanced oil recovery, geothermal energy production, and subsurface contaminant migration could be used to further model percutaneous absorption. The human health section includes a review of the geophysical imaging methods that have been used for imaging the interior of the human body, including electrical impedance tomography and magnetic induction tomography.Accurate 3D interpretations of surface or near surface voltage/current or electromagnetic field measurements are dependent upon the inversion algorithms used. EIT impedance inversion is computationally less challenging than EM induction inversion, but rapid and resource-efficient solutions are being developed for geophysical applications. Details of this report can be found at

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“…The impedivity data extracted from injection currents and voltage measurements in the EIT system when the RSC models are placed between electrodes in the E-phantom is compared with the impedance results that are determined using the ColeCole equation in order to assess the performance of the image reconstruction algorithm. This means simulating the impedance of different physical phenomena (in this case electrical properties of Carcinoma, Fat and Stroma tissues) at different frequency points [14,25,26].…”

Section: Rsc Modelmentioning

confidence: 99%

A 3D multi-frequency response electrical mesh phantom for validation of the planar structure EIT system performance

Zarafshani

Qureshi

Bach

et al. 2016

2016 IEEE International Conference on Electro Information Technology (EIT)

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Abstract-Assessment and validation of the Electrical Impedance Tomography (EIT) system performance and calibration of systematic errors in the electrical field generated inside of the interrogated volume is an important requirement. System instabilities can be caused by the EIT design and must be characterized before and during the clinical trials. Evaluation of the Sussex EIT system used in the clinical study can be based on a realistic electronic phantom. We designed a mesh phantom based on the electrode configuration and mesh structures of the image reconstruction. The phantom has the capability of modelling the cellular electrical properties that are operative within a circular homogeneous medium. The design is optimized to assess the planar topology of the internal impedance distribution. The system employs the information from the electrical properties of biological tissues to evaluate the Cole-Cole dispersion data. This mesh phantom is capable of producing localized conductivity perturbations between each arbitrary channel in the electrode placement planar phantom topology by measuring all 1416 combinations that are to be used in the image reconstruction. The phantom is especially designed for the Sussex EIT system to validate system performance of measurements consisting of SNR, and modelling system accuracy.

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Preliminary results from an EIT breast imaging simulation system

Cited by 23 publications

References 11 publications

Performance Evaluation of Five Types of Ag/AgCl Bio-Electrodes for Cerebral Electrical Impedance Tomography

Performance Evaluation of Five Types of Ag/AgCl Bio-Electrodes for Cerebral Electrical Impedance Tomography

Linking the Geosciences to Emerging Bio-Engineering Technologies

A 3D multi-frequency response electrical mesh phantom for validation of the planar structure EIT system performance

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