Preliminary investigation of the association of oral lichen planus and hepatitis C

Jv, Bagan; Ramon, C.; González, L. Blasco; Diago, M.; Milián, Maria Angeles; Cors, R.; Lloria, E.; Cardona, Francisco; Jiménez, Yolanda

doi:10.1016/s1079-2104(98)90286-4

Cited by 86 publications

(89 citation statements)

References 37 publications

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“…Although the etiology of OLP remains uncertain, there have been reports that described many systemic disorders linked to OLP such as metabolic syndrome [25], mental disorders [26], immune disease [27,28] and viral infection [29]. The association of these pathologies with OLP appears to depend upon geographic factors [30].…”

Section: Discussionmentioning

confidence: 99%

Thyroid Disease and Oral Lichen Planus as Comorbidity: A Prospective Case-Control Study

García-Pola¹,

Llorente-Pendás²,

Romero³

et al. 2016

Dermatology

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Background: Thyroid disease has been mentioned to have a possible relation to the development of oral lichen planus (OLP). Objective: Because goiter is considered endemic in many countries, we proposed to determine whether thyroid disease constitutes a comorbidity of OLP. Methods: Two hundred and fifteen patients diagnosed as having OLP were evaluated concerning their serum thyroid-stimulating hormone and thyroxine (T₄) levels. The results were contrasted with those obtained in control series of the same number of subjects matched for age and sex. Results: Diagnosis of thyroid disease was present in 15.3% of OLP patients (33/215) and in 5.2% (12/215) of the control group. In relation to OLP patients, the odds ratio of presence of thyroid disorders was 3.06 and that of using levothyroxine medication 3.21. Conclusions: In the present study, OLP patients were associated with thyroid disease, specifically with hypothyroidism. Because most thyroid patients need T₄ treatment, our findings confirmed that OLP and thyroid disease could be comorbidities.

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Section: Discussionmentioning

confidence: 99%

Thyroid Disease and Oral Lichen Planus as Comorbidity: A Prospective Case-Control Study

García-Pola¹,

Llorente-Pendás²,

Romero³

et al. 2016

Dermatology

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“…They suggested that a chronic graft-versus-host-like autoimmune reaction might have been responsible for the pathogenesis, involving possible cross-reactivity between HBsAg use in HBV vaccines and shared epitopes on keratinocytes. Bagán et al (25) have concluded that there is an association between hepatitis C virus infection and oral lichen planus. In our present series, a small proportion of the patients had associated malignancy.…”

Section: Discussionmentioning

confidence: 99%

Meteorological influences on the incidence of lichen planus in a north Indian population

et al. 2013

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“…Due to its association with OLP, the presence of C-hepatitis virus has been suggested in several reports (15)(16)(17). The histopathologic pattern in first biopsy was not completely elucidatory, being compatible with both OLP and GVHD.…”

Section: Discussionmentioning

confidence: 99%

Squamous cell carcinoma of the tongue after bone marrow transplantation in a patient with Fanconi anemia

Salum

Martins²,

Figueiredo

et al. 2006

Braz. Dent. J.

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Fanconi anemia (FA) is an autosomal recessive disorder that might cause a variety of congenital and developmental abnormalities. The most important features of FA are progressive bone marrow failure and development of malignancies, particularly acute myeloid leukemia and solid tumors. This paper reports the case of a 12-year-old patient with FA assisted at the Stomatology and Bucomaxillofacial Cancer Prevention Service of São Lucas Hospital, Brazil, who had been submitted to bone marrow transplantation (BMT) at the age of 5 and exhibited oral lesions characteristic of chronic graft versus host disease (GVHD). The patient was treated and followed-up for the oral lesions. Eleven years after the BMT, he developed squamous cell carcinoma of the tongue with an aggressive behavior, which was considered an untreatable condition. The patient died few months later from asphyxia at the age of 16. The reasons for development of these malignant conditions are unknown. However, chromosomal instability typically observed in FA cases, BMT factors and GVHD have been considered. Systematic follow-up of these patients allows early and less invasive therapeutic approaches.

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Preliminary investigation of the association of oral lichen planus and hepatitis C

Cited by 86 publications

References 37 publications

Thyroid Disease and Oral Lichen Planus as Comorbidity: A Prospective Case-Control Study

Thyroid Disease and Oral Lichen Planus as Comorbidity: A Prospective Case-Control Study

Meteorological influences on the incidence of lichen planus in a north Indian population

Squamous cell carcinoma of the tongue after bone marrow transplantation in a patient with Fanconi anemia

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