Preliminary Experience with Carbon Dioxide Therapy In the Treatment of Pressure Ulcers In a Bedridden Elderly Patient

Piazzolla, Luciana Paganini; Louzada, Luciana Lilian; Scoralick, Francisca Magalhães; Martins, M.; Sousa, João Batista de

doi:10.1111/j.1532-5415.2011.03806.x

Cited by 14 publications

(13 citation statements)

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“…Therapeutic indications of CO 2 therapy include vascular, cardiac, metabolic and rheumatic diseases, cellulite, chronic wounds, localized adiposities, migraine headaches. It is used, as well, in radiology to guided catheters placement and in laparoscopic surgeries for visualization of the surgical field [3][4][5][6][8][9][10][11][12][13][14][15][16][17] . CO 2 therapy is safe, with low cost, no toxicity or side effects [3][4][5]12,17 .…”

Section: Introductionmentioning

confidence: 99%

The effect of carbon dioxide therapy on composite graft survival

Duraes

Carneiro

et al. 2013

Acta Cir. Bras.

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PURPOSE:To investigate the effect of carboxytherapy in auricular composite grafts in rabbits. METHODS:An experimental study was conducted using 20 rabbits randomly assigned to a treatment group of carboxytherapy or a control group of saline solution. In each ear, a circular graft with 1.5 cm or 2 cm of diameter was amputated and reattached. Animals underwent carbon dioxide or saline injection four times during the experiment. We analyzed clinical evolution of the animals, grafts survival, histopathology features and histomorphometry of collagen. RESULTS:The treated group had a significantly lower weight gain (p=0.038). Histopathology was not significantly different between groups. There was an increase in amount of collagen in 2 cm grafts submitted to carbon dioxide therapy (p=0.003). Carboxytherapy didn't influence graft survival rate for 1.5 cm grafts or 2 cm grafts (p=0.567 and p=0.777, respectively). CONCLUSIONS:Carbon dioxide therapy increased the amount of collagen in 2 cm grafts. CO 2 was not significantly different from saline infusion on composite grafts survival, but this study suggests that there is a mechanical effect caused by distension which favored graft survival.

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Section: Introductionmentioning

confidence: 99%

The effect of carbon dioxide therapy on composite graft survival

Duraes

Carneiro

et al. 2013

Acta Cir. Bras.

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“…As a fi nal consequence of the reduction in pH and the release of mediators, vasomotor effects on the microcirculation, neoangiogenesis and fibrogenesis in the extracellular matrix are observed 4,9 . Ito et al 5 using CO 2 percutaneously, provided experimental support for the clinical use of CO 2 -enriched water bathing in the treatment of skin circulatory disorders and ulcers.…”

Section: Discussionmentioning

confidence: 99%

“…4 , in a preliminary experience with carbon dioxide therapy in the treatment of pressure ulcers in a bedridden elderly patient, this treatment is especially beneficial for elderly adults with pressure ulcers due to immobility because they may have injections at home, avoiding hospitalization. healing ulcer and difficult-to-heal ulcers emphasize the need for specific therapies for each type of wound 14 .…”

Section: Discussionmentioning

confidence: 99%

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Effects of carbon dioxide therapy on the healing of acute skin wounds induced on the back of rats

Penhavel¹,

Nascimento²,

Duraes³

et al. 2013

Acta Cir. Bras.

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PURPOSE:To evaluate the healing effect of carbon dioxide therapy on skin wounds induced on the back of rats. METHODS:Sixteen rats underwent excision of a round dermal-epidermal dorsal skin flap of 2.5 cm in diameter. The animals were divided into two groups, as follows: carbon dioxide group -subcutaneous injections of carbon dioxide on the day of operation and at three, six and nine days postoperatively; control group -no postoperative wound treatment. Wounds were photographed on the day of operation and at six and 14 days postoperatively for analysis of wound area and major diameter. All animals were euthanized on day 14 after surgery. The dorsal skin and the underlying muscle layer containing the wound were resected for histopathological analysis. RESULTS:There was no statistically significant difference between groups in the percentage of wound closure, in histopathological findings, or in the reduction of wound area and major diameter at 14 days postoperatively. CONCLUSION:Under the experimental conditions in which this study was conducted, carbon dioxide therapy had no effects on the healing of acute skin wounds in rats.

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“…При этом происходит кор-рекция тканевой гипоксии бла-годаря эффекту Бора, воздей-ствию на факторы роста эндо-телия, стимуляции неоангиоге-неза и фибробластов, синтезу коллагена, что приводит к луч-шему заживлению ран (диабе-тических, ишемических, после-операционных и посттравмати-ческих) [1,31,33].…”

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