Preliminary experience with 2-octylcyanoacrylate in a pediatric emergency department

Abstract

Octylcyanoacrylate adhesives performed well in the daily practice of a pediatric emergency department, and were used for a significant percentage of laceration closures. Convenience, average infection rates, and good parental satisfaction make tissue adhesives a valuable addition to our wound closure techniques. Certain pitfalls occurring during early experience with these adhesives can be recognized and avoided.

A Prospective Controlled Study on Long-Term Outcomes of Facial Lacerations in Children

“…Lowe (41) noticed that one of the most important predictors of parental satisfaction in pediatric laceration repair is "provider performance, " comprising communication, attitude, hygiene and confidence of the physician. Many studies naturally address the parental point of view, (41,42) as self-reports are limited by age, but thus accept that self-reported health-related QoL potentially differs from proxy assessment (43). The CDLQI, which was used in the present population, is the most widely used instrument for measuring skin-related QoL in children (20).…”

A prospective comparison of octyl-2-cyanoacrylate and suture in standardized facial wounds

“…This derivative has a longer side chain and forms a stronger and more flexible bond, with a three-dimensional breaking strength four times that of butyl-2-cyanoacrylate 6,12 . Several investigations into the cosmetic results of wound closure have been published in the last few years, but most were performed in children 4,8,18 , with the results difficult to transfer to facial wounds in adults, and in many studies the wounds were not standardized for length, localization and shape 11,22 . The results also conflict with regard to the cosmetic results of wound closure with adhesives as opposed to sutures; whereas some authors reported superior results for wound closure with sutures 1,21 , other studies demonstrated better or equal cosmetic results with cyanoacrylates 8,22 .…”

Periorbital infections after Dermabond closure of traumatic lacerations in three children

“…( J AAPOS 2012;16: 168-172) I n previous studies authors have documented the benefits of wound closure with tissue adhesives compared with sutured wound closure. [1][2][3][4][5][6][7] The purpose of this report is to describe cases of periorbital cellulitis after wound closure of traumatic periorbital lacerations with 2-octyl cyanoacrylate (Dermabond; Ethicon, Inc, Somerville, NJ) and to evaluate the existing literature to identify a trend toward an increased infection rate with tissue adhesive closure.…”