Preliminary evaluation of the short‐term outcomes of polytetrafluoroethylene mesh for pelvic organ prolapse

Abstract

Aim Tension‐free vaginal mesh (TVM) surgery using synthetic polypropylene (PP) soft mesh had spread rapidly. However, the frequency of mesh‐related postoperative complications had increased, and PP was banned in April 2019. In Japan, however, transvaginal surgery using polytetrafluoroethylene (PTFE) mesh had been approved. In this study, we evaluated the clinical outcome and quality of life (QOL) of the postoperative course using PP mesh and PTFE mesh (named “ORIHIME™”) in a combination surgery for utero‐sacral ligament suspension and anterior vaginal support using anterior TVM. Methods The vaginal hysterectomy and utero‐sacral ligament colpopexy augmented by anterior vaginal mesh implants using PP mesh and PTFE mesh were performed on patients with stage III to IV cystocele and uterine prolapse. The clinical outcome and QOL changes in their postoperative course were evaluated by comparing 15 cases of PP mesh and 13 cases of PTFE mesh. Results There was no difference between the PP group and PTFE group in characteristics. No mesh‐related complications occurred during the follow‐up period. With regard to the pelvic organ prolapse quantification (POP‐Q) score, no significant difference was found between the two groups. Comparing the postoperative QOL of both groups, the PTFE group had significantly higher values in two domains than PP group (SF‐12v2 questionnaire). Conclusions We used the world's first PTFE mesh to compare PP mesh with postoperative POP‐Q and QOL after the same surgery, with the same operator, and at the same institution. The results showed no significant difference between both mesh materials in the short‐term.

Quality of Life Following Pelvic Organ Prolapse Treatments in Women: A Systematic Review and Meta-Analysis

“…There were two main procedures for vaginal surgeries: reconstructive (in two subgroups, including repair with natural tissue [ 17 , 19 , 20 , 23 , 24 , 31 , 36 , 37 , 38 , 60 , 61 , 63 , 64 , 65 , 66 ] ( Table 2 ) and repair with mesh [ 7 , 9 , 12 , 21 , 25 , 26 , 29 , 32 , 35 , 39 , 40 , 41 , 42 , 43 , 44 , 55 , 62 , 67 , 68 , 69 , 78 , 82 , 83 , 85 ]) ( Table 3 ) and obliterative surgeries [ 18 , 27 , 60 , 71 , 72 , 73 , 86 ] ( Table 4 ). In one study, obliterative surgery and sacrospinous fixation in older postmenopausal women were compared, and the QoL was better in the sacrospinous group [ 18 ].…”

Long‐term follow up in two cases of pelvic reconstruction using a combined VRAM flap‐sacrocolpopexy for severe perineal hernia after abdominoperineal resection

“…Proline mesh, however, is no longer used worldwide due to its various complications, and it is therefore necessary to consider performing sacrocolpopexy more safely by utilizing other, improved types of mesh. For example, in Japan, PTFE mesh has been introduced as a new type of mesh, and its use has been reported 10 . As a further advantage of this technique, flap filling not only fills the dead space, but it also keeps the distance between the bowel resection site and the mesh itself, which is thought to help prevent the occurrence of mesh complications.…”

“…For example, in Japan, PTFE mesh has been introduced as a new type of mesh, and its use has been reported. 10 As a further advantage of this technique, flap filling not only fills the dead space, but it also keeps the distance between the bowel resection site and the mesh itself, which is thought to help prevent the occurrence of mesh complications.…”

Сучасні Підходи До Лікування Генітального Пролапсу У Жінок З Екстрагенітальною Патологією

“…Після розсмоктування синтетичних ниток обсяг стороннього матеріалу, що зберігається в організмі, зменшується на 60 %. Тому основні переваги сіток, що частково розсмоктуються, це зменшення маси сітки, великий розмір пор і більша відстань між волокнами, що сприяє утворенню гнучкої «рубцевої сітки», а не ригідної «рубцевої пластини», і в організмі жінки залишається менш ніж 40 % первісного матеріалу сітки [15].…”