Preliminary evaluation of a three-dimensional, customized, and preformed titanium mesh in peri-implant alveolar bone regeneration

Abstract

ObjectivesThe purpose of this preliminary study is to evaluate the effectiveness of a customized, three-dimensional, preformed titanium mesh as a barrier membrane for peri-implant alveolar bone regeneration.Materials and MethodsTen patients were recruited for this study. At the time of implant placement, all patients had fenestration or a dehiscence defect around the implant fixture. A mixture of particulate intraoral autologous bone and freeze-dried bone allograft was applied to the defect in a 1 : 1 volume ratio and covered by the preformed titanium mesh. A core biopsy specimen was taken from the regenerated bone four months postoperatively. Patients were followed for 12 months after the definitive prosthesis was placed.ResultsSatisfactory bone regeneration with limited fibrous tissue was detected beneath the preformed titanium mesh. Histologic findings revealed that newly formed bones were well-incorporated into the allografts and connective tissue. New growth was composed of approximately 80% vital bone, 5% fibrous marrow tissue, and 15% remaining allograft. All implants were functional without any significant complications.ConclusionThe use of preformed titanium mesh may support bone regeneration by maintaining space for new bone growth through its macro-pores. This preliminary study presents the efficacy of a preformed titanium mesh as a ready-to-use barrier membrane around peri-implant alveolar bone defect. This preformed mesh is also convenient to apply and to remove.

Alveolar Ridge Reconstruction with Titanium Meshes and Simultaneous Implant Placement: A Retrospective, Multicenter Clinical Study

“…In another study of Jung and colleagues [26], ten patients with dehiscences or fenestrations at the time of implant placement were treated with a mixture of autogenous bone particulate and allograft covered and protected by a preformed titanium mesh, which was fixed directly on the implant neck. No complications were reported in the postoperative period nor in the following months [26].…”

“…No complications were reported in the postoperative period nor in the following months [26]. Four months after placement, small biopsies were taken from the regenerated areas: these specimens demonstrated successful and satisfactory bone regeneration, with 80% vital bone, 5% fibrous marrow tissue, and 15% remaining allograft [26]. All implants were successfully in function after a period of 1 year [26].…”

“…Four months after placement, small biopsies were taken from the regenerated areas: these specimens demonstrated successful and satisfactory bone regeneration, with 80% vital bone, 5% fibrous marrow tissue, and 15% remaining allograft [26]. All implants were successfully in function after a period of 1 year [26]. The authors concluded that the use of preformed titanium meshes can represent a reliable treatment procedure around peri-implant alveolar bone defects: in addition, they are extremely easy to apply, by fixing them on the implant shoulder, and simple to remove [26].…”

“…All implants were successfully in function after a period of 1 year [26]. The authors concluded that the use of preformed titanium meshes can represent a reliable treatment procedure around peri-implant alveolar bone defects: in addition, they are extremely easy to apply, by fixing them on the implant shoulder, and simple to remove [26]. …”

“…Not least, they are easy to handle and can be easily adapted to the site and fixed directly to the implant, allowing the surgeon to sculpt the contours of the alveolar tissue to be regenerated. The ease of use is a key factor, since the easier is the application and adaptation of the membrane, the greater are the chances of success of regenerative therapy [15, 18, 26]. In this context, the possibility to have membranes of different sizes and shapes can be extremely helpful for the surgeon.…”