Preliminary data on the association between waist circumference and insulin resistance in children without a previous diagnosis

Rodríguez-Rodríguez, Elena; Palmeros-Exsome, Carolina; López-Sobaler, Ana M.; Ortega, Rosa M.

doi:10.1007/s00431-010-1260-1

Cited by 26 publications

(34 citation statements)

References 51 publications

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“…Additionally the hip circumference had no correlation with the insulin resistance in our study population. There are few studies which have examined the associations between anthropometric measures of obesity and insulin resistance in children or adolescents [34][35][36][37][38][39]. Our findings are partially in line with those of other researchers.…”

Section: Discussionsupporting

confidence: 82%

New surrogate anthropometrical markers for early detection of insulin resistance

Porwal

Singh

Verma

et al. 2015

Int Jour of Biomed Res

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Background: Insulin resistance is the pathophysiological basis of several cardiometabolic risk conditions. The early identification of insulin resistance decreases the risk of cardiometabolic complications. The correlation between the increase in visceral fat, central obesity and with insulin resistance is a important indicator. Present study was conducted to find the correlation between various anthropometric measurements and insulin resistance (HOMA-IR) and to find out the anthropometric marker, which correlates most significantly with insulin resistance. Material and methods: This is a population based cross-sectional study. Total 100 apparently healthy subjects (n=55 male and n=45 female) aged between 18-25 years were recruited with prior ethical approval and with written informed consent. All the anthropometrical measurements were done as per the standard methods. Fasting glucose and insulin were estimated by using commercially available kit. Insulin resistance was quantified using homeostasis model Results: There was positive correlation between HOMA-IR and waist circumference (r=0.395, p=0.0001). However, significant positive & mild correlation between HOMA-IR and waist hip ratio was found (r=0.263, p =0.008). The correlation between HOMA-IR and waist height ratio was also observed to be positive and moderate. Conclusion: As per the findings we concluded that, waist circumference and waist height ratio are better predictors of insulin resistance compared to the other anthropometric measurements in apparently healthy north Indian subjects.

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Section: Discussionsupporting

confidence: 82%

New surrogate anthropometrical markers for early detection of insulin resistance

Porwal

Singh

Verma

et al. 2015

Int Jour of Biomed Res

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“…Concerning the associations of various anthropometric indices with IR proxy measures and plasma glucose levels, limited data are available [18,24,25,29,34,42]. In particular, Yan et al have revealed that WC, WHtR and BMI are similarly correlated with fasting serum insulin (I F ), and HOMA [42].…”

Section: Introductionmentioning

confidence: 97%

Comparison of several anthropometric indices with insulin resistance proxy measures among European adolescents: The Helena Study

et al. 2010

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The aim of the current study was to compare the association of several anthropometric indices, with insulin resistance (IR) proxy measures in European adolescents. The present study comprises 1,097 adolescents aged 12.5-17.5 from ten European cities participating in the HELENA study. Weight, height, waist circumference (WC) and hip circumference, skinfolds thickness, fat mass (FM), fasting plasma glucose (G(F)) and serum insulin (I(F)) levels were measured. HOMA (as indicator of IR body mass index (BMI), waist to hip ratio (WHR) and waist to height ratio (WHtR) were calculated. I(F) and HOMA were statistically significantly related to BMI, WC, skinfold sum, WHtR, WHR and FM. BMI, WC, WHtR, skinfold sum and FM displayed similar correlation with I(F) and HOMA as opposed to WHR where lower correlation with IR indices was detected in the overall sample. Similar results were found for boys, girls and underweight/normal weight adolescents. On the other hand, WC and WHtR were found to be more strongly associated with IR proxy measures compared to the rest of anthropometric indices among overweight/obese subjects. Based on the current findings, WC and WHtR could be used, alternatively, to identify the overweight/obese adolescent at risk for developing IR. In addition, all aforementioned anthropometric indices, except WHR, could be used among the underweight/normal weight adolescents.

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“…Few studies have considered alternative measures of obesity in children and those that have (22,25,26) report inconsistent findings. Although the choice of BMI as a measure of obesity in children is well established (27) there is emerging evidence to suggest that central adiposity in children is more relevant to health outcomes than overall adiposity estimated by BMI (28,29). Also the prevalence of central adiposity (measured by waist circumference) is considerably higher than the prevalence of general obesity (measured by BMI) and is increasing at a faster rate (22,30,31).…”

Section: Introductionmentioning

confidence: 99%

Area-level deprivation and adiposity in children: is the relationship linear?

2013

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Objective: It has been suggested that childhood obesity is inversely associated with deprivation, such that the prevalence is higher in more deprived groups. However, comparatively few studies actually use an area level measure of deprivation limiting the scope to assess trends in the association with obesity for this indicator. Furthermore, most assume a linear relationship. Therefore, the aim of this study was to investigate associations between area level deprivation and three measures of adiposity: body mass index (BMI), waist circumference (WC) and waist-to-height ratio (WHtR) in children.Design: Cross sectional study, data collected on 3 occasions a year apart (2005 -2007) Subjects: Data was available for 13333 children, typically aged 11-12 years from 37 schools and 542 Lower Super Output Areas (LSOAs).Measures: Stature, mass and WC. Obesity was defined as a BMI and WC exceeding the 95 th centile according to British reference data. WHtR exceeding 0.5 defined obesity. The Index of Multiple Deprivation affecting children (IDACI) was used to determine area level deprivation.Results: Considerable differences in the prevalence of obesity exist between the three different measures. However, for all measures of adiposity the highest probability of being classified obese is in the middle of the IDACI range. This relationship is more marked in girls, such that the probability of being obese for girls living in areas at the two extremes of deprivation is around half that at the peak, occurring in the middle. Conclusion:These data confirm the high prevalence of obesity in children and suggest that the relationship between obesity and residential area level deprivation is not linear. This is contrary to the 'deprivation theory' and questions the current understanding and interpretation of the relationship between obesity and deprivation in children. These results could help make informed decisions at the local level.

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Preliminary data on the association between waist circumference and insulin resistance in children without a previous diagnosis

Cited by 26 publications

References 51 publications

New surrogate anthropometrical markers for early detection of insulin resistance

New surrogate anthropometrical markers for early detection of insulin resistance

Comparison of several anthropometric indices with insulin resistance proxy measures among European adolescents: The Helena Study

Area-level deprivation and adiposity in children: is the relationship linear?

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