Preliminary clinical study of LenSx femtosecond laser-assisted limbal relaxing incision on correction of high myopia with low to moderate astigmatism in posterior implantable collamer lens implantation

Abstract

<jats:title>Abstract</jats:title> <jats:p>BackgroundTo evaluate the safety, efficacy, and predictability of the LenSx femtosecond laser-assisted limbal relaxing incision (LRI) for correction of high myopia with low to moderate corneal astigmatism (-0.75 to -1.50D) in implantable collamer lens implantation (ICL).MethodsThis prospective clinical control study included 56 eyes from 46 patients. They were divided into an ICL group with ICL implantation (14 patients,16 eyes); a TICL group with toric ICL implantation (17 patients, 23 eyes); and a LenSx + ICL group with a LenSx femtosecond laser-assisted LRI and an ICL implantation (15 patients, 17 eyes). The visual acuity, astigmatism correction ability and visual quality were measured before and 1, 3, and 6 months after surgery.ResultsThe postoperative visual acuity of the 3 groups were higher than the preoperative visual acuity (P &lt; 0.01), and the improvements in the LenSx + ICL group and the TICL group were greater than those in the ICL group (P &lt; 0.01). The LenSx + ICL and TICL groups had less residual astigmatism and higher astigmatism correction index (CI) than the ICL group (P &lt; 0.01). There was no significant difference in the three groups of total high order aberrations (HOAs) before and after surgery (P &gt; 0.05).ConclusionLenSx femtosecond laser-assisted LRI combined with ICL implantation can effectively correct low to moderate corneal astigmatism in high myopia. Compared with TICL implantation, it can achieve similar clinical effects in the short term.Trial registrationThis<jats:bold> </jats:bold>article has been retrospectively registered at the Chinese Clinical Trial Registry in 10 June 2019. (NO: ChiCTR1900023743).</jats:p>