Abstract:In vitro fertilization (IVF) in conjunction with preimplantation genetic diagnosis (PGD) for mutation detection and human leukocyte antigen (HLA) matching for hematopoietic stem cell transplantation (HSCT) is a unique technology of modern clinical embryology. The technology should be offered to any family with a condition that requires matched-related HSCT. Today, PGD-HLA matching is a realistic option for families in need of treating an affected sibling, when no HLA-matched donor is available. Offering the op… Show more
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