Pregnant Dutch Women Have Inadequate Iodine Status and Selenium Intake

Mayunga, K. Clara; Lim-A-Po, Melany; Lubberts, Janniek; Stoutjesdijk, Eline; Touw, Daan; Muskiet, Frits A. J.; Dijck-Brouwer, D. A. J.

doi:10.3390/nu14193936

Cited by 6 publications

(8 citation statements)

References 58 publications

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“…Dineva et al reported a median urinary iodine to creatinine ratio of 210 µg/g [26], which is above the cut-off value of 150 µg/L for insufficiency. Mayunga et al reported, however, a median ratio of 141 µg/g, where 58% of the women had insufficient iodine concentrations [99]. A total of 40% of the women used iodine-containing supplements, of which 29% used a dose of 75 µg per day and 17% a dose of 150 µg per day [99].…”

Section: Vitamin C Iron and Magnesiummentioning

confidence: 99%

An Evaluation of Food and Nutrient Intake among Pregnant Women in The Netherlands: A Systematic Review

2023

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Nutritional deficiencies during pregnancy can have serious consequences for the health of the (unborn) child. This systematic review provides an updated overview of the available food and nutrient intake data for pregnant women in The Netherlands and an evaluation based on the current recommendations. Embase, MEDLINE, and national institute databases were used. Articles were selected if they had been published since 2008 and contained data on food consumption, nutrient intake, or the status of healthy pregnant women. A qualitative comparison was made with the 2021 Dutch Health Council recommendations and reference values. A total of 218 reports were included, representing 54 individual studies. Dietary assessments were primarily performed via food frequency questionnaires. Protein, vitamin A, thiamin, riboflavin, vitamin B6, folate, vitamin B12, vitamin C, iron, calcium, and magnesium intakes seemed to be adequate. For folate and vitamin D, supplements were needed to reach the recommended intake. The reasons for concern are the low intakes of fruits, vegetables, and (fatty) fish, and the intakes of alcohol, sugary drinks, and salt. For several foods and nutrients, no or limited intake data were found. High-quality, representative, and recent data are needed to evaluate the nutrient intake of pregnant women in order to make accurate assessments and evaluations, supporting scientific-based advice and national nutritional policies.

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Section: Vitamin C Iron and Magnesiummentioning

confidence: 99%

An Evaluation of Food and Nutrient Intake among Pregnant Women in The Netherlands: A Systematic Review

2023

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“…At present many pregnant Dutch women have low iodine status [ 150 ]. They also have poor selenium status and 61% are both iodine and selenium deficient [ 151 ]. Currently 88% of the global population uses iodized salt, and the number of countries with according to the World Health Organization (WHO) adequate iodine intake has nearly doubled from 67 in 2003 to 118 in 2020.…”

Section: Considerations Pertaining To Iodine and Selenium Dietary Ref...mentioning

confidence: 99%

Thyroidal and Extrathyroidal Requirements for Iodine and Selenium: A Combined Evolutionary and (Patho)Physiological Approach

Dijck-Brouwer

Muskiet²,

Verheesen³

et al. 2022

Nutrients

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Iodide is an antioxidant, oxidant and thyroid hormone constituent. Selenoproteins are needed for triiodothyronine synthesis, its deactivation and iodine release. They also protect thyroidal and extrathyroidal tissues from hydrogen peroxide used in the ‘peroxidase partner system’. This system produces thyroid hormone and reactive iodine in exocrine glands to kill microbes. Exocrine glands recycle iodine and with high urinary clearance require constant dietary supply, unlike the thyroid. Disbalanced iodine-selenium explains relations between thyroid autoimmune disease (TAD) and cancer of thyroid and exocrine organs, notably stomach, breast, and prostate. Seafood is iodine unconstrained, but selenium constrained. Terrestrial food contains little iodine while selenium ranges from highly deficient to highly toxic. Iodine vs. TAD is U-shaped, but only low selenium relates to TAD. Oxidative stress from low selenium, and infection from disbalanced iodine-selenium, may generate cancer of thyroid and exocrine glands. Traditional Japanese diet resembles our ancient seashore-based diet and relates to aforementioned diseases. Adequate iodine might be in the milligram range but is toxic at low selenium. Optimal selenoprotein-P at 105 µg selenium/day agrees with Japanese intakes. Selenium upper limit may remain at 300–400 µg/day. Seafood combines iodine, selenium and other critical nutrients. It brings us back to the seashore diet that made us what we currently still are.

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“…And Mayunga K.C. et al reported inadequate iodine levels in pregnant Dutch women [32]. Because as there is no enough information about their selenium intake, we examined iodine status and selenium intake in relation to iodine and selenium supplementation during pregnancy.…”

Section: Introductionmentioning

confidence: 98%

Increased Morbidity and Its Possible Link to Impaired Selenium Status

Hajibala¹,

Maharram²

2023

Selenium and Human Health

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This chapter summarizes the latest information on the main differences in the chemical properties of selenium proteins and their sulfur analogues, Se proteins and their functions, Se-accumulating proteins, the relationship between Se and hemoglobin, Selenium in gerontology, Selenium and iodine deficiency conditions, Se and immunity, Selenium as an antioxidant in nitrite poisoning. Also discussed are some of the results of the first studies on protein enrichment with selenium carried out in the seventies of the last century. This native protein was natural silk fibroin. Fibroin has since become an important tool for human health and healing. It was discovered that when selenium-containing inorganic compounds were added to mulberry silkworm feed, selenium atoms formed additional sulfur-like bonds in fibroin macromolecules. This resulted in additional branching of protein macromolecule. Selenium atoms in the fibroin structure have a sufficiently high electron affinity, act as small traps and capture migrating electrons. This leads to a reduction of free radicals, which are generated by external influences such as mechanical, thermal, electrical and radiation.

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Pregnant Dutch Women Have Inadequate Iodine Status and Selenium Intake

Cited by 6 publications

References 58 publications

An Evaluation of Food and Nutrient Intake among Pregnant Women in The Netherlands: A Systematic Review

An Evaluation of Food and Nutrient Intake among Pregnant Women in The Netherlands: A Systematic Review

Thyroidal and Extrathyroidal Requirements for Iodine and Selenium: A Combined Evolutionary and (Patho)Physiological Approach

Increased Morbidity and Its Possible Link to Impaired Selenium Status

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