Pregnancy-Specific β-1-Glycoprotein in First-Trimester Maternal Serum Is Influenced by Smoking

Abstract

PEG precipitation has limitations of which users of this technique should be aware (5 ), and gel filtration chromatography remains the gold standard. Nevertheless, PEG precipitation remains the most practical approach available for screening for macroprolactinemia. We believe that in the interests of clarity and good laboratory practice, it is time to abandon reporting results as percentage macroprolactin in favor of the absolute post-PEG prolactin concentration, together with an appropriate reference interval. In differentiating between true hyperprolactinemia and macroprolactinemia, this approach will serve to facilitate interpretation of the result, provide more clinically useful information, and enhance patient care.

Pregnancy Specific β-1 Glycoprotein 1 is Expressed in Pancreatic Ductal Adenocarcinoma and its Subcellular Localization Correlates with Overall Survival

“…PSGs are mostly renowned for their abundant placental expression during pregnancy 2, which results in elevated PSG plasma levels. Below-average PSG plasma levels in pregnant women have been associated with “small for gestation age” (SGA) fetuses 6 and first-trimester maternal plasma levels of PSG1 have been shown to be influenced by smoking 7.…”