Pregnancy-related microchimerism unknown pathophysiological effects

Davies, David; Demırhan, Osman

doi:10.15761/fwh.1000167

Search citation statements

Order By: Relevance

Paper Sections

Select...

Microchimerism Can Be a Part Of The Immune System Transmitti...1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2022

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

(1 citation statement)

References 52 publications

(60 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition, it has been associated with the triggering of chronic inflammatory autoimmune diseases due to maternal tissue compatibility of these cells. Infectious diseases also increase physiological cell migration between mother and fetüs (Davies D & Demirhan O., 2019). Thus, the mother's cellular immune system goes out of routine and becomes more active to protect the fetus.…”

Section: Microchimerism Can Be a Part Of The Immune System Transmitti...mentioning

confidence: 99%

Physiological and Pathological Effects of Fetal and Maternal Microchimerism

Demırhan

2022

CRMS

View full text Add to dashboard Cite

Microchimerism (Mc) is a bidirectional exchange of fetal and maternal cells during pregnancy. Pregnancy is the most common and natural cause of chimerism. Therefore, we are all born as microchimera. Although there are many unanswered questions it is thought that chimerism has an important role in human health. For many years, the clinical effects of microchimeric cells (McCs) in organ repair and cancer therapy have just begun to be understood. While the mission of chimerism is straight forward, the subject is profound. Chimerism carries the potential for disease as well as for health benefits. This article describes the role of Mc in the etiology of psychotic disorders. In this review, we consider Mc to be a physiological phenomenon, but it can also transform into pathology under inappropriate conditions. We describe in detail below the possible physio-pathological roles of F-MMcCs.

show abstract

Section: Microchimerism Can Be a Part Of The Immune System Transmitti...mentioning

confidence: 99%