2020
DOI: 10.18203/2320-6012.ijrms20202273
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Pregnancy outcome in women with intrahepatic cholestasis of pregnancy

Abstract: Background: Intrahepatic cholestasis of pregnancy is a multifactorial condition of pregnancy diagnosed when otherwise unexplained pruritus with abnormal liver function test and neither of which has an alternative cause. The most appropriate gestational age for the delivery of women with ICP is yet to be determined. The present study is designed to determine whether with active intervention, pregnancy with ICP can be carried to a later gestation.Methods: Fifty Women with diagnosed a case of ICP were recruited i… Show more

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“…The role of estrogen and progesterone in the etiology of OC has been proven, so this condition is more common in women with multifetal pregnancies and after oral progesterone treatment [6]. Special caution and monitoring is needed in patients with OC because of the risk of poor perinatal outcome such as: premature birth, meconium in the amniotic fluid, fetal bradycardia, fetal distress, and unfortunately intrauterine fetal death and stillbirth [7]. Intrahepatic cholestasis in pregnancy may be associated with significant vitamin K deficiency, severe coagulopathy and consequent lifethreatening bleeding [8,9].…”
Section: Introductionmentioning
confidence: 99%
“…The role of estrogen and progesterone in the etiology of OC has been proven, so this condition is more common in women with multifetal pregnancies and after oral progesterone treatment [6]. Special caution and monitoring is needed in patients with OC because of the risk of poor perinatal outcome such as: premature birth, meconium in the amniotic fluid, fetal bradycardia, fetal distress, and unfortunately intrauterine fetal death and stillbirth [7]. Intrahepatic cholestasis in pregnancy may be associated with significant vitamin K deficiency, severe coagulopathy and consequent lifethreatening bleeding [8,9].…”
Section: Introductionmentioning
confidence: 99%