Pregnancy Outcome in Patients With Pulmonary Arterial Hypertension Receiving Prostacyclin Therapy

Daniele, Bruno; Hod, Moshe; Oron, Galia; Sagie, Alik; Eidelman, Leonid A.; Shitrit, David; Kramer, Mordechai R.

doi:10.1097/01.aog.0000164074.64137.f1

Cited by 94 publications

(57 citation statements)

References 7 publications

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“…The patient who becomes pregnant should be informed of the high risk of pregnancy and termination of the pregnancy should be discussed. Those patients who choose to continue pregnancy should be treated with disease-targeted therapies, planned elective delivery and effective close collaboration between obstetricians and the PAH team [163,164].…”

Section: Pregnancy Birth Control and Post-menopausal Hormonal Therapymentioning

confidence: 99%

2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension

et al. 2015

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Guidelines summarize and evaluate all available evidence on a particular issue at the time of the writing process, with the aim of assisting health professionals in selecting the best management strategies for an individual patient with a given condition, taking into account the impact on outcome, as well as the risk–benefit ratio of particular diagnostic or therapeutic means. Guidelines and recommendations should help health professionals to make decisions in their daily practice. However, the final decisions concerning an individual patient must be made by the responsible health professional(s) in consultation with the patient and caregiver as appropriate.

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Section: Pregnancy Birth Control and Post-menopausal Hormonal Therapymentioning

confidence: 99%

2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension

et al. 2015

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“…Pacjentkę, która zajdzie w ciążę należy poinformować o wysokim ryzyku ciąży i omówić z nią możliwość przerwania ciąży. Pacjentki, które zdecydują się na kontynuowanie ciąży, należy leczyć metodami swoistymi dla choroby, zapewnić im planowe rozwiązanie ciąży oraz ustalić bliską współpracę między położnikiem a zespołem leczącym PAH [163,164]. Nie jest jasne, czy hormonalna terapia zastępcza u kobiet po menopauzie z PH jest warta zalecenia.…”

Section: Ciąża Antykoncepcja I Hormonalna Terapia Zastępcza Po Menopunclassified

2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension

Galiè¹,

Humbert²,

Vachiéry³

et al. 2015

Kardiol Pol

356

528

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“…(46) In a more recent study, 3 stable patients on prostacyclin therapy and lowmolecular-weight heparin were able to successfully complete pregnancy. (47) Pregnant cyanotic women have a high risk of fetal loss. Also, cyanosis is a recognized handicap to fetal growth, resulting in low birth weight infants.…”

Section: Outcome Of Pregnancy In Eisenmenger Syndrome or Other Causesmentioning

confidence: 99%

Pregnancy, Genetic Risk and Congenital Heart Disease

Jost

Connolly

2017

SAHJ

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An increasing number of women with congenital heart disease (CHD) are reaching childbearing age and are considering pregnancy. Pregnancy is tolerated well in most of these women with unoperated, or repaired cardiac lesions; however, the risk is increased considerably in certain situations such as pulmonary hypertension, severe valvular stenosis, pulmonary atresia, mechanical prosthetic valves, with Fontan type circulation, in Marfan syndrome and other aortopathy. Counseling prior to pregnancy in CHD also involves discussion of genetic testing, possibility of transmission to the child, management during pregnancy including preimplantation genetic testing, and recommendations regarding fetal echocardiography. All medications including anticoagulation options if needed should be carefully reviewed prior to pregnancy due to maternal and fetal risks. If needed, cardiac surgery or balloon valvuloplasty can be carried out with an increased risk to mother and fetus. Overall, pregnancy in CHD is feasible in most patients with good maternal and fetal outcome. High risk pregnancy patients with CHD have to be counseled by a multidisciplinary team including cardiologists, obstetricians and anesthesiologists at a tertiary care center. ABSTRACT PREGNANCY AND CONGENITAL HEART DISEASE

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Pregnancy Outcome in Patients With Pulmonary Arterial Hypertension Receiving Prostacyclin Therapy

Abstract: Pregnancy in women with pulmonary hypertension should still be considered high risk for both mother and child, but stable patients on epoprostenol may successfully complete pregnancy.

Cited by 94 publications

References 7 publications

2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension

2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension

2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension

Pregnancy, Genetic Risk and Congenital Heart Disease

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