Pregnancy Outcome in Hyperthyroidism: A Case Control Study

Aggarawal, Neelam; Suri, Vanita; Singla, Rimpi; Chopra, Seema; Sikka, Pooja; Shah, Viral N.; Bhansali, Anil

doi:10.1159/000357615

Cited by 87 publications

(76 citation statements)

References 19 publications

(30 reference statements)

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“…It's retrospective nature does not allow us to obtain additional detailed information regarding potential confounding factors such as pregnancy complications [29,30], mode of delivery, maternal education, and lifestyle during pregnancy. Identical anthropometric measurements could not be performed for all pregnant women throughout the research period.…”

Section: Discussionmentioning

confidence: 99%

Risk Factors for Low Birth Weight Infants in Japanese Pregnancies: A One-year Study of 2551 Cases in Tokyo

Arima¹,

Kasai²,

Sugimoto³

et al. 2017

Int J Pediatr Neonat Care

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Background: The rate of low-birth weight infants in Japan has been increasing. Being underweight and increasing maternal age are risk factors for delivering low birthweight infants. Currently, pregnant Japanese women exhibit these risk factors for delivering low birthweight infants; however, little research has been conducted. This study aimed to investigate the associations between pregnancy characteristics in Japanese women and low birth weight infants. Methods: We enrolled 2551 pregnant women at >36 weeks of gestation and who delivered in metropolitan Tokyo. Pre-pregnancy body mass index was categorized using the World Health Organization classification. Gestational weight gain and birth weight were categorized based on the guidelines of the Ministry of Health, Labour and Welfare, Japan. The differences in pregnancy characteristics among three birth-weight categories,i.e., low birth weight, normal, and macrosomia, were assessed using the chisquare test. The risk ratios of low birth weight were estimated using logistic regression analysis. Results: In Japanese pregnancies, birth weight was associated with gestational week at delivery, gestational weight gain, pre-pregnancy body mass index, sex, parity, and maternal age (P<0.05). In particular, the risk of low birth weight increased with advanced maternal age (odds ratio=1.97), insufficient gestational week at delivery (odds ratio=9.00), low gestational weight gain (odds ratio=2.76), and female infant (odds ratio=2.06). Further, it decreased in multiparous women compared with that in primiparous women (odds ratio=0.57). Conclusions: These findings suggest that pregnant Japanese women who are ≥40 years old with a gestational weight gain of <7.0 kg, <37 gestational weeks at delivery, female baby, and primiparous should be checked carefully during the gestational period. In order to decrease the risk of low birth weight babies, women should be educated early about childbearing and pregnancy.

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Section: Discussionmentioning

confidence: 99%

Risk Factors for Low Birth Weight Infants in Japanese Pregnancies: A One-year Study of 2551 Cases in Tokyo

Arima¹,

Kasai²,

Sugimoto³

et al. 2017

Int J Pediatr Neonat Care

View full text Add to dashboard Cite

show abstract

“…The reason for excluding cesarean section was to form a more uniform cohort of very low risk parturient women with minimal obstetric intervention. Complications of pregnancy were defined as serious problems that are associated with pregnancy such as hypertensive disorders, preeclampsia [10], gestational diabetes, thromboembolic events, hyperthyroidism [11], etc. Complications of pregnancy were not exclusion criteria but rather their presence precluded inclusion in the study.…”

Section: Methodsmentioning

confidence: 99%

Total and Differential Leukocyte Count Percentiles in Healthy Singleton Term Women during the First Stage of Labor

Lurie

Weiner

Golan

et al. 2014

Gynecol Obstet Invest

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Aims: To establish leukocyte count and differential percentiles in healthy singleton term laboring women during spontaneous normal vaginal labor following an uncomplicated pregnancy. Methods: An analysis of the records of all women (n = 762) who delivered at our delivery ward during a 2-month period was performed. After exclusion for cesarean delivery, induction of labor, pregnancy complications, preterm labor, multiple pregnancy, fever on admission, and lack of full blood count on admission, 365 parturient women during the 1st stage of labor were included in the final analysis. The total and differential leukocyte counts were determined by standard procedure by an automated cell counter. Results: The leukocyte count range on admission to the delivery ward during the 1st stage of labor in healthy parturient women was between 4.4 × and 21.7 × 10³/µl and the 99th percentile limit was 20.06 × 10³/µl. The total leukocyte count was not influenced by cervical dilatation, ruptured membranes, or the presence and regularity of uterine contractions. Conclusion: An observed leukocyte count within the 99th percentile limit (20.06 × 10³/µl) in an otherwise normal parturient woman is reassuring in the absence of other clinical evidence.

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“…Une hyperthyroïdie maternelle non é quilibré e peut être responsable de complications maternelles (insuffisance cardiaque principalement) mais surtout obsté tricales comme la pré maturité (OR = 3,94), le retard de croissance intra-uté rin (OR = 1,73), le diabè te gestationnel (OR = 1,8) et enfin le recours à une cé sarienne (OR = 1,47) [22,23]. Les risques pour l'enfant à naître sont, d'aprè s des é tudes ré trospectives ré centes, la survenue d'une thyrotoxicose foetale ou né o-natale avec un risque corré lé au titre des TRAK pendant la grossesse [24], ainsi que la survenue d'autisme et d'hyperactivité [25].…”

Section: Hyperthyroïdieunclassified