2016
DOI: 10.1053/j.ajkd.2016.04.022
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Pregnancy in Women With CKD: A Success Story

Abstract: In women with chronic kidney disease (CKD), pregnancy outcomes have improved over the last 50 years, particularly in the developed world. Maternal mortality is now extremely low, fetal survival has markedly increased (even in women with CKD stages 4-5), and it is now the exception for women with CKD to be advised against embarking on a pregnancy. However, pregnancies are rarely free from complications, and there are unanswered questions about the longer term effects on maternal and infant health. The developme… Show more

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Cited by 53 publications
(64 citation statements)
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“…CKD is a risk factor for adverse pregnancy outcomes from its early stages (Table I) (6,38,39). The risks increase from CKD stage 1 to CKD stage 5, and may be higher in glomerular nephropathies, autoimmune diseases, and diabetic nephropathy (6,7,(38)(39)(40)(41).…”
Section: Chronic Kidney Diseasementioning
confidence: 99%
See 1 more Smart Citation
“…CKD is a risk factor for adverse pregnancy outcomes from its early stages (Table I) (6,38,39). The risks increase from CKD stage 1 to CKD stage 5, and may be higher in glomerular nephropathies, autoimmune diseases, and diabetic nephropathy (6,7,(38)(39)(40)(41).…”
Section: Chronic Kidney Diseasementioning
confidence: 99%
“…The risks increase from CKD stage 1 to CKD stage 5, and may be higher in glomerular nephropathies, autoimmune diseases, and diabetic nephropathy (6,7,(38)(39)(40)(41). Results of pregnancy after kidney donation suggest that reduction of kidney parenchyma may be associated with a higher risk of PE and hypertensive disorders of pregnancy (42,43).…”
Section: Chronic Kidney Diseasementioning
confidence: 99%
“…administration of folic acid and iron supplements) contributed the most to increased fetal survival rates, they are not the only factors. Increased understanding of CKD and renal physiology during pregnancy contributed significantly as well (5). Pregnant women experience prominent changes in the physiology of kidney function.…”
Section: Implication For Health Policy/practice/research/medical Educmentioning
confidence: 99%
“…Other coexisting conditions should be considered when a pregnant woman with CKD prepares for pregnancy. Managing each of these conditions, usually covered in pre-pregnancy counseling for highrisk women, in addition to CKD improves pregnancy outcomes significantly (5). Despite all the progresses in different aspects of managing CKD, before, during and after the gestational period, many issues remain unresolved.…”
Section: Implication For Health Policy/practice/research/medical Educmentioning
confidence: 99%
“…These two words may describe how obstetric nephrology has shifted from the description of very rare cases, to the development of a complex new and fascinating branch of medicine, that counterbalances obstetricians' usually optimistic outlook by focusing on subtle challenges posed by chronic diseases, and mitigate the frequently grim approach of nephrologists, with a message of hope: women with kidney disease can have the same basic life goals as healthy women their age [1,2] (Fig. 1).…”
mentioning
confidence: 99%