Pregnancy in Patients after Homograft Cardiac Valve Replacement

Denbow, C E; Matadial, L; Sivapragasam, S; Spencer, H

doi:10.1378/chest.83.3.540

Cited by 21 publications

(8 citation statements)

References 13 publications

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“…Most of the women in this study with a bioprosthesis went through pregnancy successfully without anticoagulant treatment. The fetal outcome was excellent and our data for this group do not differ from the normal population.6 This accords with previous reports.3 [7][8][9] The outcome was only slightly less favourable for the babies of mothers with mechanical valves. The difference did not reach statistical significance, except for prematurity.…”

Section: Mechanical Valvessupporting

confidence: 91%

Outcome of pregnancy in women with valve prostheses.

Sbarouni

1994

Heart

280

124

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(Br Heart3 1994;71:196-201) There is still no consensus on the most suitable heart valve replacement for women of childbearing age. Mechanical valves carry a risk of thromboembolism and the need for anticoagulation whereas bioprostheses have a lower thromboembolic risk but are not as durable, particularly in the young. There is controversy about the safest anticoagulant regimen during pregnancy. Early reports of pregnancy in women with mechanical valves were usually of anecdotal cases: they were inspired by disaster rather than by success. Most of these reports came from the United States where overanticoagulation was the rule because of the use of thromboplastins of low responsiveness.' There is still no universal adoption of the International Normalised Ratio (INR)

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Section: Mechanical Valvessupporting

confidence: 91%

Outcome of pregnancy in women with valve prostheses.

Sbarouni

1994

Heart

280

124

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“…According to the data cited in literature, about 30% of biological valves are subject to premature degeneration in the course of pregnancy, requiring reimplantation of the defective valve [30]. Among the biological valves, it is actually the homografts that had proven by far the most durable [31,32].…”

Section: Discussionmentioning

confidence: 99%

Clinical and echocardiographic assessment of pregnant women with valvular heart diseases—maternal and fetal outcome

Leśniak‐Sobelga

Tracz

Kostkiewicz

et al. 2004

International Journal of Cardiology

130

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“…study, which showed a high rate of fetal loss regardless of warfarin dose (13). Use of warfarin during pregnancy might also be associated with fatal hemorrhage in the fetus and central nervous system abnormalities (68).…”

Section: Management Of Complicationsmentioning

confidence: 99%

Valvular Heart Disease and Pregnancy

Elkayam

Bitar

2005

Journal of the American College of Cardiology

231

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A large number of prosthetic heart valves (PHV) are being implanted in patients with both congenital and acquired valvular disease. Many of the recipients of such valves are women of childbearing age who desire to have children. The main issues involved with pregnancy in a patient with PHV include the selection of PHV in women during their childbearing age, risks to both the mother and the fetus associated with pregnancy and the management of the patients with PHV during gestation.

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Pregnancy in Patients after Homograft Cardiac Valve Replacement

Cited by 21 publications

References 13 publications

Outcome of pregnancy in women with valve prostheses.

Outcome of pregnancy in women with valve prostheses.

Clinical and echocardiographic assessment of pregnant women with valvular heart diseases—maternal and fetal outcome

Valvular Heart Disease and Pregnancy

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