Pregnancy in congenital cardiac disease: an increasing challenge for cardiologists and obstetricians - a prospective multicenter study

Abstract

Most women with CCD and a good functional class before pregnancy tolerate pregnancy without major problems. However, pregnancy may induce serious cardiac and obstetric complications. The specific risks require an individualized multidisciplinary patient-management by experienced physicians.

Pregnancy-Related Obstetric and Cardiologic Problems in Women After Atrial Switch Operation for Transposition of the Great Arteries

“…12 The impact of pregnancy on systemic RV function in women after ASO is therefore a concern. 3, 13 In the present study, a decrease in ventricular function occurred in 2 women during their first pregnancy, in 1 during her second pregnancy and in 1 during her third pregnancy. Three of the 4 women (75%) did not return to their pre-pregnancy level of RV function.…”

Pregnancy outcome in women with repaired versus unrepaired isolated ventricular septal defect

“…3,4 In the present study we found a low rate of cardiac events during pregnancy, which is in agreement with the small amount of existing literature. [5][6][7][8] The risk of obstetric events was associated with the corrective status. The presence of an unrepaired VSD was associated with a higher risk of pre-eclampsia (8.7%).…”

“…3,4 Despite the fact that a VSD is one of the most common forms of heart disease among pregnant women, VSD-specific pregnancy data are limited. [5][6][7][8] A recent literature review of studies published between 1985 and 2007 found a total of 83 completed pregnancies among women with VSDs (combining repaired and unrepaired VSD). 9 The current consensus is that pregnancy in women with an isolated VSD is generally well tolerated, with no maternal mortality and no significant maternal or fetal morbidity.…”

Antikoagulation und Gerinnungsstörungen in der Schwangerschaft

“…In dieses Patientenkollektiv gehören Patientinnen mit schweren kongenitalen Herzerkrankungen, die in immer größerer Zahl nach erfolgreicher operativer oder interventioneller Behandlung das Erwachsenenalter erreichen [25], sowie Patientinnen mit Klappenprothesen oder mit Vorhofflimmern [28]. Die Beratung und Versorgung dieser Patientinnen stellt hohe Anforderungen an die betreuenden Ärzte und bedingt eine interdisziplinäre Zusammenarbeit von Hausärzten, Internisten, Kardiologen und Frauenärzten.…”