Pregnancy in Chronic Hemodialysis Patients in the Kingdom of Saudi Arabia

Souqiyyeh, Muhammad Ziad; Huraib, Sameer; Saleh, Abdul Ghayoum Mohd.; Aswad, S.

doi:10.1016/s0272-6386(13)80003-0

Cited by 109 publications

(89 citation statements)

References 8 publications

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“…In general, North Africa and the Middle East were cited as high prevalence areas, both in the general population and in HD patients, by the WHO in 1999 [9] . Previous studies from the region have reported a prevalence of anti-HCV antibodies in HD patients of 50% in Saudi Arabia in 2000 [10] , 19.1% in Tunisia in 1994 [11] , 20.2% in Turkey in 2006 [12] and 34.6% in Jordan in 2007 [13] . Concerning the prevalence of HBV, Abourached et al [5] reported on 2007 a prevalence of 2.62% (0%-6.5%) of HBsAg in 17 HD centers in Lebanon, our study showed a decrease of the prevalence to 1.6%, ranging from 1.4% in Nabatieh and Bekaa, to 2.4% in the North.…”

Section: Resultsmentioning

confidence: 99%

Incidence and prevalence of hepatitis B and hepatitis C viruses in hemodialysis patients in Lebanon

Rached

Khoury

Imad

et al. 2016

WJN

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AIM:To determine the incidence and the prevalence of hepatitis B and C viral infections in patients on hemodialysis (HD) across Lebanon. METHODS:We reviewed the data registry at the Lebanese Ministry of Public Health where records of monthly hepatitis B surface antigen (HBsAg) and hepatitis C virus (HCV) serology are reported from 60 affiliated HD centers across Lebanon. All patients who were on HD or who started HD between October 2010 and July 2012 were included in the study. Patients from seven HD centers were excluded due to inadequate and incomplete results reporting. During the selected Retrospective Study ORIGINAL ARTICLEperiod, HBsAg and HCV serology were available for 3769 patients from 53 HD centers distributed at all Lebanese governorates. The prevalence was calculated by dividing the number of patients with positive HBsAg or HCV serology to the total number of patients. The Incidence was calculated by dividing the number of newly acquired infection to number of patients-years (p-y). Incidence rates at different governorates were compared to each other using two tailed Z test and a P value of < 0.05 was considered significant. RESULTS:Sixty out of 3769 HD patients were found to have positive HBS Ag and 177 out of 3769 were positive for HCV Antibodies. The prevalence of hepatitis B virus (HBV) and HCV in HD patients across Lebanon was 1.6%, and 4.7%, respectively. The comparison of prevalence according to geographic distribution could not be done accurately due to the frequent shift of patients between dialysis centers at different governorates. The incidence rate was 0.27 per 100 p-y for HBV and 0.37 per 100 p-y for HCV. There was no significant difference concerning the incidence of HBV between HD centers at different governorates (all P values > 0.1), but this difference was highly significant concerning the incidence rates of HCV which occurred predominantly in the southern centers (1.47 per 100 p-y) with a P value of 0.00068 and 0.00374 when compared to Mount Lebanon (0.21 per 100 p-y) and the Northern centers (0.19 per 100 p-y), respectively. CONCLUSION:The incidence rate of HBV and HCV is very low in the Lebanese HD centers and their prevalence is decreasing over the last two decades.

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Section: Resultsmentioning

confidence: 99%

Incidence and prevalence of hepatitis B and hepatitis C viruses in hemodialysis patients in Lebanon

Rached

Khoury

Imad

et al. 2016

WJN

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“…Since increasing dialysis frequency lowers predialysis BUN levels, adequate dialysis may reduce the occurrence of polyhydramnios and thus lower the risk of premature labor (1). Increasing the dialysis dose prolongs gestation, resulting in a higher infant birth weight and thus an infant with better chance of survival (3,17).…”

Section: Discussionmentioning

confidence: 99%

“…Because maternal hypertension is associated with at least half of the cases of obstetric hemorrhage, abruptio placentae, and anemia, pregnant women on dialysis are more likely to experience these complications. However, such complications are rarely reported (3,23). Antihypertensive medications are often required and the mainstays of treatment are methyldopa, B-blockers, and hydralazine.…”

Section: Discussionmentioning

confidence: 99%

“…Maternal mortality is very low and rarely reported (3,11). Cesarean section delivery is common among women on dialysis and is most often prompted by premature rupture of membranes.…”

Section: Discussionmentioning

confidence: 99%

“…In the saudi society, the result of a survey concerned with the frequency of pregnancy reported an incidence of 7% over five years period (1.4 per year) in end stage renal disease (ESRD) women undergoing regular hemodialysis, which may reflect the cultural endorsement of having offspring (3,4). In 2005 Malik GH et al (5) reported a yearly frequency of 0.66 in female patients on maintenance hemodialysis and none on chronic peritoneal dialysis.…”

Section: Introductionmentioning

confidence: 99%

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