Pregnancy during Adolescence and Associated Risks: An 8-Year Hospital-Based Cohort Study (2007–2014) in Romania, the Country with the Highest Rate of Teenage Pregnancy in Europe

Abstract

Aim. To determine pregnancy and delivery outcomes among teenagers. Materials and Methods. An 8-year retrospective comparative hospital-based cohort study is analysing singleton pregnancy comorbidities and delivery parameters of a teenage group under the age of 20 compared with a young adult group 20–24 years of age in a university hospital. Results. Teenage is a risk factor for preterm birth <37 weeks (1.21 [1.08–1.35]), foetal growth restriction (1.34 [1.21–1.48]), episiotomy (1.27 [1.21–1.34]), uterine revision (1.15 [1.06–1.25]), APGAR <7 at 1 min (2.42 [1.21–1.67]), cephalopelvic disproportion (1.26 [1.07–1.48]), and postpartum haemorrhage (1.42 [1.25–1.62]); however, caesarean delivery occurs less frequently in teenagers than in adults (0.75 [0.70–0.80]). The following comorbidities are risk factors for teenage pregnancy (risk ratio [CI 95%]): anaemia (1.13 [1.10–1.17]), low urinary tract infection (1.10 [1.03–1.18]), pediculosis (2.42 [1.90–3.00]), anogenital condyloma (1.50 [1.04–2.17]), and trichomoniasis (1.74 [1.12–2.68]). The risks for hepatitis B and hepatitis C, premature rupture of membranes, and placenta praevia were lower compared with those in the young adult group, respectively, 0.43 (0.26–0.71), 0.90 (0.85–0.96), and 0.29 (0.20–0.41), while the risk for gestational diabetes and preeclampsia were the same in both groups. Conclusion. Considering the high risks for teenage pregnancy, this information should be provided to pregnant adolescent women and their caregivers.

The adverse maternal and perinatal outcomes of adolescent pregnancy: a cross sectional study in Hebei, China

“…The risk of cesarean delivery in adolescent pregnancy reduced by 25% than adult pregnancy, which was consistent with the previous found, with aRR (95%CI) varying from 0.49 (0.42-0.59) to 0.79 (0.75-0.89) [1,2,13,16,28,29]. In fact, adolescent women were at the stage of physical growth, with immature reproductive system, and the incidence of cephalopelvic disproportion in adolescent pregnancy was higher than that of adult women [30].…”

“…The adverse maternal outcomes of the adolescent pregnant had no difference from those of adult pregnant in our study, such as in PE, placenta previa, placental abruption, postpartum hemorrhage, and some studies were consistent with our findings [13,16,25,26,29]. Some studies found that adolescent pregnancy increased the risk of postpartum hemorrhage [1,16]and PE [1].…”

The Effect of Antiviral Therapy on Lipid Metabolism in Patients with Viral Hepatitis C

“…Age is an important aspect in the acquisition of hepatitis C virus because it is a factor that gives information about the the most common route of transmission wich differs in children compared to adults, the chances of spontaneous clearance, and possible comorbidities associated that play an important role in progression to cirrhosis and hepatocarcinoma [13]. As the most common route of transmission in children is vertical, it is important to educate mothers about measures that can reduce the risk of transmission during and after birth [14]. In children and adolescents fulminant forms of hepatitis are rare compared to adults.…”

The influence of the Municipal Human Development Index compared to maternal education on infant mortality: a retrospective cohort study in the extreme south of Brazil

“…Although most mothers were between 18 and 34 years of age, the highest proportion of child deaths in the first year of life (1.2%) occurred among the children of those under 18. This age group presents a higher risk for complications, since younger women are still in the phase of physical and psychological development and, part of them, performing their studies in primary, secondary or even higher education [23,24]. Single, legally separated or widowed women presented a higher risk of death than those married or in a stable union (RR = 1.95; CI95% 1.77-2.15).…”