Pregnancy-Associated Systemic Lupus Erythematosus

Ergin, Rahime Nida

doi:10.1080/08998280.2014.11929116

Cited by 3 publications

(2 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Moreover, kidney biopsy revealed organized subcellular tubuloreticular inclusions in the endothelium, which are strongly associated with LN, albeit of higher classes than in our patient [ 5 ]. It is important to note that there have been only three previous reported cases of SLE occurring de novo in pregnancy [ 1 , 2 ]. Our patient differed in that she presented in her third trimester, which posed a diagnostic challenge for two main reasons.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

A Unique Cause of Proteinuria in Pregnancy: Class II Lupus Nephritis with Concomitant Minimal Change Disease

Kunjal

Adam-Eldien

Makary

et al. 2016

Case Rep Nephrol Dial

View full text Add to dashboard Cite

We report the case of a 22-year-old African American female who presented to another facility for routine follow-up in the 34th week of pregnancy with lower extremity swelling and nephrotic-range proteinuria. Although she was normotensive, it was initially thought that she had preeclampsia. She was monitored carefully and delivery was induced at 37 weeks of gestation. She was transferred to our hospital, where she was diagnosed with systemic lupus erythematosus (SLE) based on clinical and laboratory criteria. Renal biopsy revealed a surprising finding of minimal change disease (MCD) concomitant with class II lupus nephritis (LN). She was managed with pulses and then tapering doses of steroid therapy with dramatic resolution of the nephrotic syndrome. This case demonstrates not only the rare de novo occurrence of SLE in pregnancy, but the unique finding of MCD coexisting with class II LN. We propose that altered T cell activity may be the link between these seemingly distinct entities.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Systemic lupus erythematosus (SLE) commonly affects females of reproductive age and rarely occurs de novo in pregnancy [ 1 , 2 ]. Roughly 60% of SLE patients develop lupus nephritis (LN) with increased risk of neonatal and maternal morbidity [ 3 ].…”

Section: Introductionmentioning

confidence: 99%