Pregnancy and Perinatal Outcomes Associated with Acinetobacter baumannii Infection

He, Mai; Kostadinov, Stefan; Gündoğan, Füsun; Struminsky, Judith; Pınar, Halit; Sung, Chih‐Chien

doi:10.1055/s-0033-1334460

Cited by 9 publications

(2 citation statements)

References 10 publications

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“…It is unlikely that UTI leads to PE (Loh et al, 2007). He and colleagues believe that UTI increases pyelonephritis, cystitis and kidney problemsin pregnancy and patients are at risk of increased blood pressure and PE (He et al, 2013). However, in another study conducted in Croatia, it was shown that treatment of UTI in pregnant women with insulin-dependent diabetes mellitus (and not in healthy pregnant women) reduces the chance of acute pyelonephritis and PE (Drazancićet al, 1972).…”

Section: Discussionmentioning

confidence: 99%

Urinary Tract Infection (UTI) as a Risk Factor of Severe Preeclampsia

Izadi¹,

Rostami-Far²,

Jalilian³

et al. 2016

GJHS

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Background: Urinary tract infection (UTI) is a very common medical complication of pregnancy. The aim of this study is to determine the incidence of UTI in preeclamptic pregnancies and its association with severity of this disease.Methods: This cohort study was performed on 71 women with mild preeclampsia (PE), 70 women with severe PE, and 98 healthy pregnant women from October 2012 to April 2014 in the west of Iran. Mean diastolic pressure and level of proteinuria were used as indicators of disease severity. The main criteria for diagnosis of UTI was microbial count of higher than 10 4 cfu/ml. Results:The prevalence of the UTI in severe PE patients was significantly higher than mild PE patients and non-hypertensive pregnants. 12 out of 70 women with severe PE (17.1%) and 7 out of 98 controls (7.1%) had UTI (P<0.05), also 8 out of 71 women with mild PE (11.3%) had UTI (P>0.05). Conclusions:Our data shows a significant increase in UTI in severe PE pregnancy. Thus, we can consider UTI as one of the risk factors for developing severe PE; so by screening UTI in the first visit of the pregnant women and repeating it at the second and third trimester of pregnancy we could decrease adverse effects of UTI such as severe PE in pregnant women.

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Section: Discussionmentioning

confidence: 99%

Urinary Tract Infection (UTI) as a Risk Factor of Severe Preeclampsia

Izadi¹,

Rostami-Far²,

Jalilian³

et al. 2016

GJHS

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“…CorrZIDF Acinetobacter Acinetobacter infection in adverse pregnancy and perinatal outcomes [31,32] Aerococcus Low abundance in preterms [33] Atopobium High relative abundance of Atopobium vaginae at the midtrimester was highly predictive of preterm birth [34] Bacteroides Abundance reduction in Bacteroides in women who delivered preterm [35,36] Brevibacterium Occasionally found in the placenta, considered as contaminants [37] Campylobacter Associated with an increased risk of spontaneous abortion, stillbirth, and preterm delivery [38] Fusobacterium Associated with preterm birth and has been isolated from the amniotic fluid, placenta, and chorioamnionic membranes of women delivering prematurely [39] Mobiluncus For women with a prior preterm delivery, high level of Mobiluncus significantly indicate a spontaneous preterm delivery [40] Oligella Mostly found as a commensal organism of the human genitourinary tract, which is also the main infection site [41] Peptostreptococcus Pregnant women with Bacterial vaginosis including Peptostreptococcus and other bacteria have increased risk of preterm labor and preterm premature rupture of membranes.…”

Section: Genus Relevance Referencementioning

confidence: 99%

A Distribution-Free Model for Longitudinal Metagenomic Count Data

Luo

Liu

Chen

et al. 2022

Genes

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Longitudinal metagenomics has been widely studied in the recent decade to provide valuable insight for understanding microbial dynamics. The correlation within each subject can be observed across repeated measurements. However, previous methods that assume independent correlation may suffer from incorrect inferences. In addition, methods that do account for intra-sample correlation may not be applicable for count data. We proposed a distribution-free approach, namely CorrZIDF, which extends the current method to model correlated zero-inflated metagenomic count data, offering a powerful and accurate solution for detecting significance features. This method can handle different working correlation structures without specifying each margin distribution of the count data. Through simulation studies, we have shown the robustness of CorrZIDF when selecting a working correlation structure for repeated measures studies to enhance the efficiency of estimation. We also compared four methods using two real datasets, and the new proposed method identified more unique features that were reported previously on the relevant research.

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Pathogens Identified by Minimally Invasive Tissue Sampling in India and Pakistan From Preterm Neonatal Deaths: The PURPOSE Study

Ghanchi

Ahmed

Kim

et al. 2022

Clinical Infectious Diseases

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Background We identified pathogens found in internal organs and placentas of deceased preterm infants cared for in hospitals in India and Pakistan. Methods Prospective, observational study conducted in delivery units and NICUs. Tissue samples from deceased neonates obtained by minimally invasive tissue sampling (MITS) and placentas were examined for 73 different pathogens using multiplex PCR. Results Tissue for pathogen PCR was obtained from liver, lung, brain, blood, cerebrospinal fluid (CSF) and placentas from 377 deceased preterm infants. Between 17.6% and 34.1% of each type of tissue had at least one organism identified. Organism detection was highest in blood (34.1%), followed by lung (31.1%), liver (23.3%), CSF (22.3%) and brain (17.6%). 49.7% of the deceased infants had at least one organism. Acinetobacter baumannii was in 28.4% of the neonates compared to 14.6% for Klebsiella pneumoniae, 11.9% for E. coli/Shigella, and 11.1% for Haemophilus influenzae. Group B Streptococcus (GBS) was identified in only 1.3% of the neonatal deaths. A. baumannii was rarely found in the placenta and was found more commonly in the internal organs of neonates who died later in the neonatal period. The most common organism found in placentas was Ureaplasma urealyticum in 34% of the samples, with no other organism found in ≥ 4% of samples. Conclusions In organ samples from deceased infants in India and Pakistan, evaluated with multiplex pathogen PCR, A. baumannii was the most commonly identified organism. GBS was rarely found. A. baumannii was rarely found in the placentas of these deceased neonates.

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Pregnancy and Perinatal Outcomes Associated with Acinetobacter baumannii Infection

Cited by 9 publications

References 10 publications

Urinary Tract Infection (UTI) as a Risk Factor of Severe Preeclampsia

Urinary Tract Infection (UTI) as a Risk Factor of Severe Preeclampsia

A Distribution-Free Model for Longitudinal Metagenomic Count Data

Pathogens Identified by Minimally Invasive Tissue Sampling in India and Pakistan From Preterm Neonatal Deaths: The PURPOSE Study

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