Pregnancy and ischemic stroke: a practical guide to management

Alebeek, Mayte E van; Heus, Roel de; Tuladhar, Anil M.; Leeuw, Frank Erik de

doi:10.1097/wco.0000000000000522

Cited by 46 publications

(41 citation statements)

References 64 publications

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“…Although considered a somewhat scarce occurrence, ischemic strokes associated with pregnancy carry higher mortality rates. The risk is at its highest from the third trimester until 6 weeks postpartum [9]. In countries like India and Mexico, pregnancy-related stroke is not that uncommon and is caused by dural sinus thrombosis [10].…”

Section: Risk Factorsmentioning

confidence: 99%

Ischemic Stroke in Young Adults: Practical Diagnosis Guide

Mihai¹,

Pleşa²,

Axelerad³

et al. 2021

Ischemic Stroke

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With its increasing incidence in younger population and as a leading cause of disability, ischemic stroke represents a real public health problem. This chapter aims to evaluate the most common risk factors and causes for ischemic stroke in the young. Though some are identical to those found in older patients, most of them are specific to this population segment. Furthermore, another objective is to provide some guidance in approaching the case based on some important clinical clues. Due to the lack of universal management guidelines, it is up to the physician to judge the particularities of each case and to carry out the variety of investigations necessary for determining the cause.

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Section: Risk Factorsmentioning

confidence: 99%

Ischemic Stroke in Young Adults: Practical Diagnosis Guide

Mihai¹,

Pleşa²,

Axelerad³

et al. 2021

Ischemic Stroke

View full text Add to dashboard Cite

show abstract

“…However, the findings in the study should be interpreted with caution due to the small number of outcome events in subgroups [ 34 ]. Although evidence is insufficient to make clear evidence-based recommendations about stroke prevention in pregnant women, Mayte et al summarized a practical guide to manage ischemic stroke during pregnancy, and suggested that aspirin (50–150 mg/day), which is well-tolerated during pregnancy, could be considered for women with higher risk of stroke, including cardioembolism, migraine, and coagulation disorders [ 35 ].…”

Section: Aspirin In Pregnancymentioning

confidence: 99%

The Potential Protective Role of Aspirin Against Migraine in Pregnant Women

Liu

Gong

2020

Med Sci Monit

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Females are highly predisposed to the occurrence of migraine, a recurrent neurovascular headache disorder. Although migraine improves or disappears during pregnancy, a significant association between migraine and hypertension (i.e., pre-eclampsia) or vascular complications (i.e., stroke) during gestation has been determined. Low-dose aspirin exerts an antithrombotic effect and can improve vascular resistance by regulating endothelial function, which are implicated in the pathogenesis of migraine, pre-eclampsia, and other vascular complications during pregnancy. Low-dose aspirin is widely used prophylactically in the general population who are at higher risk of developing stroke or in pregnant women at higher risk of pre-eclampsia. In this paper we discuss the recent trends in research on the relationship between migraine and pre-eclampsia, an issue of paramount importance in obstetric care, and the potential relationship between migraine and vascular complications in pregnant women. In addition, the potential validity of low-dose aspirin prophylaxis in pregnant women with migraine is explored.

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“…Detailed laboratory evaluation to identify possible triggering causes of the disease is also important to be performed. Pregnant patients should receive individualized treatment to ensure mother and fetus' safety [1,8], including careful evaluation of the pregnant women at the beginning of prenatal care through anamnesis, obstetric history investigation and possible previous comorbidities since these factors can be aggravated by the pregnancy cycle and lead to unfavorable outcomes [8]. Authors in the current study have herein reported two clinical cases of patients who underwent stroke episodes, one before pregnancy and the other one in the first semester of pregnancy.…”

Section: Introductionmentioning

confidence: 99%

Untitled

2020

Asp Biomed Clin Case Rep

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Cerebrovascular disease (CVD) is a neurological medical emergency and one of the main causes of death worldwide; it is classified as ischemic or hemorrhagic. The disease is one of the most severe clinical events related to pregnancy due to thrombogenesis and thrombophilia; there is an incidence of 25 to 34 CVD per 100 thousand births. The current research reports two cases of stroke episode, one previous and another during pregnancy, as well as their associated complications. The first patient had hereditary thrombophilia caused by PAI 4G/5G polymorphism and previous stroke; however, she had regular pregnancy. The second patient had hereditary thrombophilia caused by protein C deficit, had a stroke during pregnancy, and preeclampsia in the first gestational semester; therefore, she was subjected to the cesarean section on the 35 th week of pregnancy. Stroke episodes during pregnancy can be very aggressive because it can lead to death or disabilities, not only in the mother but also in the fetus. Based on the association between thrombotic processes and complications, prophylactic anticoagulant therapy is recommended for women with thrombophilia who had a stroke and/or certain adverse pregnancy outcomes, such as recurrent miscarriages.

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Pregnancy and ischemic stroke: a practical guide to management

Cited by 46 publications

References 64 publications

Ischemic Stroke in Young Adults: Practical Diagnosis Guide

Ischemic Stroke in Young Adults: Practical Diagnosis Guide

The Potential Protective Role of Aspirin Against Migraine in Pregnant Women

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