Pregnancy after renal transplantation

Abstract

OBJECTIVE: A well-functioning renal transplant usually reverses ESRD-related infertility and allows the reproductive function to improve. In this study, we wanted to emphasize that women who have renal transplantation can live healthy pregnancies with a careful follow-up. BACKGROUND: 204 patients underwent renal transplantation in our center and 84 of them were female. Five of our patients (one of them had two births) gave birth to a total of 6 pregnancies. METHOD: All of these patients were evaluated according to the criteria by the organ transplant team and perinatologist before the pregnancy planning and during the pregnancy processes. RESULTS: The mean age of the patients was 22.5 ± 4.5 (18-29) years. The creatinine level was below in 1.5 mg/dl in all patients in the pre-pregnancy period, and 1 + proteinuria was found in only two of them. Pregnancy periods varied between 31 weeks and 38 weeks. All births were performed by cesarean section and birth weight in babies ranged between 1650 and 3190 gram. CONCLUSION: Pregnancy in the renal transplant recipient is high-risk and should be managed by a multidisciplinary team of high-risk obstetricians, perinatalogists and transplant nephrologists. It should be closely monitored in terms of complications during pregnancy (Tab. 5, Ref. 16). Text in PDF www.elis.sk.

Multifaceted Sexual Dysfunction in Dialyzing Men and Women: Pathophysiology, Diagnostics, and Therapeutics

“…Secondly, since RT, hormone replacement therapy, bromocriptine, and/or frequent dialysis may restore menses, longstanding cessation of menses may be a relative state [60,61]. Regardless, fertility in women with ESRD is estimated to be reduced 10-fold [62].…”

“…RT restores fertility; however, pregnancy after RT is considered high risk, and transplant recipients are at higher risk of maternal complications such as tissue rejection, graft loss after pregnancy, preeclampsia, hypertension, and urinary tract (and other) infections. Expectant mothers are managed by a multidisciplinary team of high-risk obstetricians, perinatologists, and transplant nephrologists, and women of child-bearing age should be fully informed and counseled by the transplant team [62].…”

Embarazo y trasplante renal. Una revisión sistemática

“…Características de los estudios Entre los 18 artículos que fueron seleccionados para la realización de esta revisión, 9 estudios fueron de Europa, 3 de América del Norte, 2 de América del Sur, 2 de Cuatro de los artículos que hacen referencia al tipo de donante, destacan que casi la totalidad de la población de estudio ha recibido el órgano de un donante vivo [26][27][28][29] . Sólo un artículo estudia a mujeres con TR de donante cadáver 23 .…”

“…Respecto a los parámetros bioquímicos, desde el inicio hasta el tercer trimestre de embarazo se produce un aumento significativo del nivel de creatinina sérica en la población 26,27,29,32,39 .…”

“…Algunos autores destacan la presencia de proteinuria superior a 300 mg/24h, siendo más significativo este ascenso de proteínas en la orina en el tercer trimestre de embarazo 24,26,27,32,33 .…”